Interactor 1: KRIT1 (O00522)
Krev interaction trapped protein 1 (Krev interaction trapped 1) (Cerebral cavernous malformations 1 protein)
Gene: KRIT1
Interactor 2: CCM2 (Q9BSQ5)
Cerebral cavernous malformations 2 protein (Malcavernin)
Gene: CCM2
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.96 | 0.60 | 0.760 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 25910212, 25814554, 28514442, 33961781, 27027284, 16037064, 23007647, 17657516, 25525273, unassigned1126 |
| Identification Methods | two hybrid, affinity chromatography technology, anti tag coimmunoprecipitation, fluorescent resonance energy transfer, two hybrid bait and prey pooling approach, two hybrid array, validated two hybrid, pull down, x-ray crystallography, molecular sieving and 1 others
more... |
| Interaction Type | direct interaction, physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0003158 - endothelium development GO:0005737 - cytoplasm GO:0032991 - protein-containing complex GO:0045765 - regulation of angiogenesis |
| Homologous interactions | 1 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
