HitPredict

Interactor 1: LIRB2 (Q8N423)
Leukocyte immunoglobulin-like receptor subfamily B member 2 (LIR-2) (Leukocyte immunoglobulin-like receptor 2) (CD85 antigen-like family member D) (Immunoglobulin-like transcript 4) (ILT-4) (Monocyte/macrophage immunoglobulin-like receptor 10) (MIR-10) (CD antigen CD85d)
Gene: LILRB2

Interactor 2: Q95J06 (Q95J06)
HLA class I histocompatibility antigen A alpha chain (MHC class I antigen) (MHC class I protein) (MHC leukocyte antigen) (Major histocompatibility complex, class I, A)
Gene: HLA-A

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	27649529
Identification Methods	surface plasmon resonance
Interaction Type	physical association

Property	Details
Interacting Pfam domains	C1-set~ig, MHC_I~ig, C1-set~Ig_2, Ig_2~MHC_I
Common GO terms	GO:0006955 - immune response GO:0009986 - cell surface
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 597 Hs			1 365
+	Hs
		409446 LIRB2_HUMAN (1-597): 7.43e-130: 395: 100.00		HLAA_HUMAN (1-365): 0: 507: 92.33
+	Hs
		1209905 LIRB2_HUMAN (1-597): 7.43e-130: 395: 100.00		Q5S3G3_HUMAN (1-365): 1.23e-180: 506: 92.06
+	Hs
		1340138 LIRB1_HUMAN (1-597): 5.34e-119: 369: 76.46		Q95J06_HUMAN (1-365): 0: 520: 100.00
+	Hs
		409456 LIRB1_HUMAN (1-597): 5.34e-119: 369: 76.46		HLAA_HUMAN (1-365): 0: 507: 92.33
+	Hs
		1209906 LIRB1_HUMAN (1-597): 5.34e-119: 369: 76.46		Q5S3G3_HUMAN (1-365): 1.23e-180: 506: 92.06
+	Hs
		380091 LIRB2_HUMAN (1-597): 7.43e-130: 395: 100.00		HLAB_HUMAN (1-362): 7.08e-159: 451: 84.81
+	Hs
		520917 LIRB2_HUMAN (1-597): 7.43e-130: 395: 100.00		HLAC_HUMAN (1-364): 6.62e-153: 436: 78.63
+	Hs
		607386 LIRB2_HUMAN (1-597): 7.43e-130: 395: 100.00		HLAG_HUMAN (1-338): 4.14e-153: 436: 81.95
+	Hs
		380099 LIRB1_HUMAN (1-597): 5.34e-119: 369: 76.46		HLAB_HUMAN (1-362): 7.08e-159: 451: 84.81
+	Hs
		719727 LIRB2_HUMAN (1-597): 7.43e-130: 395: 100.00		HLAF_HUMAN (4-348): 5.65e-144: 413: 80.87
+	Hs
		520932 LIRB1_HUMAN (1-597): 5.34e-119: 369: 76.46		HLAC_HUMAN (1-364): 6.62e-153: 436: 78.63
+	Hs
		607394 LIRB1_HUMAN (1-597): 5.34e-119: 369: 76.46		HLAG_HUMAN (1-338): 4.14e-153: 436: 81.95
+	Hs
		719728 LIRB1_HUMAN (1-597): 5.34e-119: 369: 76.46		HLAF_HUMAN (4-348): 5.65e-144: 413: 80.87
+	Hs
		1133831 KI3S1_HUMAN (1-344): 8.14e-67: 224: 37.93		Q95J06_HUMAN (1-365): 0: 520: 100.00
+	Hs
		409383 KI3S1_HUMAN (1-344): 8.14e-67: 224: 37.93		HLAA_HUMAN (1-365): 0: 507: 92.33
+	Hs
		1133828 KI3S1_HUMAN (1-344): 8.14e-67: 224: 37.93		Q5SUL5_HUMAN (1-365): 1.33e-178: 501: 91.78
+	Hs
		1133827 KI3S1_HUMAN (1-344): 8.14e-67: 224: 37.93		Q546I9_HUMAN (1-362): 1.04e-163: 463: 82.60
+	Hs
		380034 KI3S1_HUMAN (1-344): 8.14e-67: 224: 37.93		HLAB_HUMAN (1-362): 7.08e-159: 451: 84.81
+	Hs
		520843 KI3S1_HUMAN (1-344): 8.14e-67: 224: 37.93		HLAC_HUMAN (1-364): 6.62e-153: 436: 78.63
+	Hs
		719712 KI3S1_HUMAN (1-344): 8.14e-67: 224: 37.93		HLAF_HUMAN (4-348): 5.65e-144: 413: 80.87