HitPredict

Interactor 1: HLAF (P30511)
HLA class I histocompatibility antigen, alpha chain F (CDA12) (HLA F antigen) (Leukocyte antigen F) (MHC class I antigen F)
Gene: HLA-F

Interactor 2: LIRB1 (Q8NHL6)
Leukocyte immunoglobulin-like receptor subfamily B member 1 (LIR-1) (Leukocyte immunoglobulin-like receptor 1) (CD85 antigen-like family member J) (Immunoglobulin-like transcript 2) (ILT-2) (Monocyte/macrophage immunoglobulin-like receptor 7) (MIR-7) (CD antigen CD85j)
Gene: LILRB1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	11169396
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	C1-set~ig, C1-set~Ig_2, MHC_I~ig, Ig_2~MHC_I
Common GO terms	GO:0005886 - plasma membrane GO:0009897 - external side of plasma membrane GO:0045953 - negative regulation of natural killer cell mediated cytotoxicity
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 346 Hs			1 650
+	Hs
		1340138 Q95J06_HUMAN (1-345): 1.6e-175: 493: 80.87		LIRB1_HUMAN (1-650): 2.1e-147: 444: 100.00
+	Hs
		409456 HLAA_HUMAN (1-345): 4.25e-171: 481: 80.29		LIRB1_HUMAN (1-650): 2.1e-147: 444: 100.00
+	Hs
		1209906 Q5S3G3_HUMAN (1-345): 2.61e-170: 479: 80.58		LIRB1_HUMAN (1-650): 2.1e-147: 444: 100.00
+	Hs
		1325618 Q95J06_HUMAN (1-345): 1.6e-175: 493: 80.87		LIRB2_HUMAN (1-650): 7.87e-118: 365: 76.31
+	Hs
		409446 HLAA_HUMAN (1-345): 4.25e-171: 481: 80.29		LIRB2_HUMAN (1-650): 7.87e-118: 365: 76.31
+	Hs
		1209905 Q5S3G3_HUMAN (1-345): 2.61e-170: 479: 80.58		LIRB2_HUMAN (1-650): 7.87e-118: 365: 76.31
+	Hs
		1133831 Q95J06_HUMAN (1-345): 1.6e-175: 493: 80.87		KI3S1_HUMAN (1-334): 1.89e-69: 232: 35.91
+	Hs
		409383 HLAA_HUMAN (1-345): 4.25e-171: 481: 80.29		KI3S1_HUMAN (1-334): 1.89e-69: 232: 35.91
+	Hs
		1133828 Q5SUL5_HUMAN (1-345): 3.22e-168: 474: 79.71		KI3S1_HUMAN (1-334): 1.89e-69: 232: 35.91
+	Hs
		409302 HLAA_HUMAN (1-345): 4.25e-171: 481: 80.29		KI3L2_HUMAN (1-334): 9.62e-64: 219: 35.91
+	Hs
		850877 Q5S3G3_HUMAN (1-345): 2.61e-170: 479: 80.58		KI3L2_HUMAN (1-334): 9.62e-64: 219: 35.91
+	Hs
		409455 HLAA_HUMAN (1-345): 4.25e-171: 481: 80.29		LIRB4_HUMAN (1-239): 7.12e-52: 187: 50.21
+	Hs
		850913 Q5S3G3_HUMAN (1-345): 2.61e-170: 479: 80.58		KI2S4_HUMAN (120-337): 7.12e-53: 185: 38.36
+	Hs
		850828 Q5S3G3_HUMAN (1-345): 2.61e-170: 479: 80.58		KI2L3_HUMAN (319-581): 7.46e-33: 131: 22.92
+	Hs
		850827 Q5RIP0_HUMAN (1-345): 1.08e-160: 455: 77.17		KI2L3_HUMAN (319-581): 7.46e-33: 131: 22.92
+	Hs
		850806 Q5RIP0_HUMAN (1-345): 1.08e-160: 455: 77.17		KI2L2_HUMAN (319-581): 6.86e-31: 125: 22.33
+	Hs
		850781 Q5RIP0_HUMAN (1-345): 1.08e-160: 455: 77.17		KI2L1_HUMAN (319-581): 1.04e-29: 122: 20.33
+	Hs
		850804 Q5D1W8_HUMAN (1-345): 3.86e-159: 451: 77.46		KI2L2_HUMAN (319-581): 6.86e-31: 125: 22.33
+	Hs
		850779 Q5D1W8_HUMAN (1-345): 3.86e-159: 451: 77.46		KI2L1_HUMAN (319-581): 1.04e-29: 122: 20.33
+	Hs
		47606 HLAA_HUMAN (1-345): 4.25e-171: 481: 80.29		A0A8I5QEB2_HUMAN (319-530): 8.97e-18: 88.2: 22.02