HitPredict

Interactor 1: MYL1 (P05976)
Myosin light chain 1/3, skeletal muscle isoform (MLC1/MLC3) (MLC1F/MLC3F) (Myosin light chain alkali 1/2) (Myosin light chain A1/A2)
Gene: MYL1

Interactor 2: ML12A (P19105)
Myosin regulatory light chain 12A (Epididymis secretory protein Li 24) (HEL-S-24) (MLC-2B) (Myosin RLC) (Myosin regulatory light chain 2, nonsarcomeric) (Myosin regulatory light chain MRLC3)
Gene: MYL12A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005509 - calcium ion binding GO:0005829 - cytosol
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 194 Hs			1 171
+	Hs
		580632 MYL6_HUMAN (46-193): 1.66e-52: 166: 74.32		ML12A_HUMAN (1-171): 2.06e-65: 199: 100.00
+	Hs
		159559 MYL6_HUMAN (46-193): 1.66e-52: 166: 74.32		ML12B_HUMAN (13-171): 4.64e-65: 198: 99.37
+	Hs
		538637 MYL6B_HUMAN (1-194): 2.51e-51: 165: 60.58		ML12A_HUMAN (1-171): 2.06e-65: 199: 100.00
+	Hs
		159536 MYL6B_HUMAN (1-194): 2.51e-51: 165: 60.58		ML12B_HUMAN (13-171): 4.64e-65: 198: 99.37
+	Hs
		624346 MYL6_HUMAN (46-193): 1.66e-52: 166: 74.32		MYL9_HUMAN (14-171): 2.29e-64: 196: 94.30
+	Hs
		538639 MYL6B_HUMAN (1-194): 2.51e-51: 165: 60.58		MYL9_HUMAN (14-171): 2.29e-64: 196: 94.30
+	Ce
		585992 MLE_CAEEL (52-193): 4.16e-33: 117: 45.07		MLR1_CAEEL (23-169): 2.25e-39: 133: 49.32
+	Ce
		585996 MLE_CAEEL (52-193): 4.16e-33: 117: 45.07		MLR2_CAEEL (23-169): 1.93e-39: 133: 49.32
+	Hs
		409438 MYL1_HUMAN (1-194): 4.79e-53: 169: 100.00		CALM1_HUMAN (16-92): 3.58e-09: 54.5: 24.69
+	Hs
		409439 MYL1_HUMAN (1-194): 4.79e-53: 169: 100.00		CALM3_HUMAN (16-92): 3.58e-09: 54.5: 24.69
+	Hs
		483914 MYL6_HUMAN (46-193): 1.66e-52: 166: 74.32		CALM1_HUMAN (16-92): 3.58e-09: 54.5: 24.69
+	Hs
		483988 MYL6_HUMAN (46-193): 1.66e-52: 166: 74.32		CALM2_HUMAN (16-92): 3.58e-09: 54.5: 24.69
+	Hs
		484091 MYL6_HUMAN (46-193): 1.66e-52: 166: 74.32		CALM3_HUMAN (16-92): 3.58e-09: 54.5: 24.69
+	Hs
		483897 MYL6B_HUMAN (1-194): 2.51e-51: 165: 60.58		CALM1_HUMAN (16-92): 3.58e-09: 54.5: 24.69
+	Hs
		483970 MYL6B_HUMAN (1-194): 2.51e-51: 165: 60.58		CALM2_HUMAN (16-92): 3.58e-09: 54.5: 24.69
+	Hs
		484054 MYL6B_HUMAN (1-194): 2.51e-51: 165: 60.58		CALM3_HUMAN (16-92): 3.58e-09: 54.5: 24.69
+	Hs
		483903 CALM1_HUMAN (44-120): 1.71e-14: 69.2: 24.68		CALL3_HUMAN (31-92): 1.25e-10: 58.2: 27.27
+	Hs
		483976 CALM2_HUMAN (44-120): 1.71e-14: 69.2: 24.68		CALL3_HUMAN (31-92): 1.25e-10: 58.2: 27.27
+	Hs
		484049 CALM3_HUMAN (44-120): 1.71e-14: 69.2: 24.68		CALM3_HUMAN (16-92): 3.58e-09: 54.5: 24.69