HitPredict

Interactor 1: SDCB1 (O00560)
Syntenin-1 (Melanoma differentiation-associated protein 9) (MDA-9) (Pro-TGF-alpha cytoplasmic domain-interacting protein 18) (TACIP18) (Scaffold protein Pbp1) (Syndecan-binding protein 1)
Gene: SDCBP

Interactor 2: PPARA (Q07869)
Peroxisome proliferator-activated receptor alpha (PPAR-alpha) (Nuclear receptor subfamily 1 group C member 1)
Gene: PPARA

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.481

Property	Details
Experiments	32296183
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0044877 - protein-containing complex binding
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 298 Hs			1 468
+	Hs
		132709 SDCB1_HUMAN (1-298): 8.79e-106: 311: 100.00		ESR1_HUMAN (11-464): 2.21e-107: 332: 18.30
+	Hs
		370138 DLG3_HUMAN (184-268): 1.4e-17: 84.8: 26.09		ESR1_HUMAN (11-464): 2.21e-107: 332: 18.30
+	Hs
		587206 GRIP1_HUMAN (111-269): 5.63e-09: 58.9: 21.86		RXRA_HUMAN (2-465): 5.7e-118: 355: 21.61
+	Hs
		740626 GRIP1_HUMAN (111-269): 5.63e-09: 58.9: 21.86		PPARG_HUMAN (1-468): 2.71e-112: 342: 54.36
+	Hs
		370053 INADL_HUMAN (7-199): 6.33e-11: 65.2: 20.71		ESR1_HUMAN (11-464): 2.21e-107: 332: 18.30
+	Mm
		817000 GRIP1_MOUSE (101-269): 4.81e-12: 68.2: 20.60		VDR_MOUSE (102-466): 3.48e-108: 329: 25.76
+	Mm
		587109 GRIP1_MOUSE (101-269): 4.81e-12: 68.2: 20.60		ESR1_MOUSE (3-464): 2.16e-105: 327: 18.62
+	Hs
		369502 DLG1_HUMAN (194-268): 6.78e-10: 61.7: 25.61		ESR1_HUMAN (11-464): 2.21e-107: 332: 18.30
+	Hs
		280012 MPDZ_HUMAN (205-287): 2.43e-09: 60.2: 14.77		ESR1_HUMAN (11-464): 2.21e-107: 332: 18.30
+	Hs
		370787 GRIP1_HUMAN (111-269): 5.63e-09: 58.9: 21.86		ESR1_HUMAN (11-464): 2.21e-107: 332: 18.30
+	Hs
		1050020 SCRIB_HUMAN (161-276): 6.09e-16: 80.2: 18.61		ESR2_HUMAN (2-465): 7.16e-99: 308: 17.18
+	Mm
		509340 GRIP1_MOUSE (101-269): 4.81e-12: 68.2: 20.60		RARA_MOUSE (19-466): 7.87e-103: 316: 26.71
+	Hs
		509998 GRIP1_HUMAN (111-269): 5.63e-09: 58.9: 21.86		VDR_HUMAN (102-466): 9.88e-107: 325: 24.69
+	Hs
		1050096 SCRIB_HUMAN (161-276): 6.09e-16: 80.2: 18.61		NR2E1_HUMAN (88-465): 5.52e-97: 298: 22.37
+	Hs
		1246417 INADL_HUMAN (7-199): 6.33e-11: 65.2: 20.71		ESR2_HUMAN (2-465): 7.16e-99: 308: 17.18
+	Hs
		1021541 DLG1_HUMAN (194-268): 6.78e-10: 61.7: 25.61		ESR2_HUMAN (2-465): 7.16e-99: 308: 17.18
+	Hs
		280019 MPDZ_HUMAN (205-287): 2.43e-09: 60.2: 14.77		NR4A1_HUMAN (5-466): 8.89e-97: 305: 21.75