HitPredict

Interactor 1: MATN2 (O00339)
Matrilin-2
Gene: MATN2

Interactor 2: CAC1A (O00555)
Voltage-dependent P/Q-type calcium channel subunit alpha-1A (Brain calcium channel I) (BI) (Calcium channel, L type, alpha-1 polypeptide isoform 4) (Voltage-gated calcium channel subunit alpha Cav2.1)
Gene: CACNA1A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.50	0.80	0.637

Property	Details
Experiments	21078624
Identification Methods	two hybrid, pull down
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	Ion_trans~VWA
Common GO terms	-
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 956 Hs			1 2506
+	Hs
		139674 FBLN4_HUMAN (421-639): 2.1e-23: 106: 28.51		CAC1A_HUMAN (1-2506): 0: 1884: 100.00
+	Hs
		139692 NOTC1_HUMAN (170-567): 1.82e-22: 106: 13.22		CAC1A_HUMAN (1-2506): 0: 1884: 100.00
+	Hs
		139751 LTBP3_HUMAN (523-671): 3.38e-21: 102: 25.97		CAC1A_HUMAN (1-2506): 0: 1884: 100.00
+	Hs
		86286 B9EG76_HUMAN (523-671): 4.15e-21: 101: 25.97		CAC1A_HUMAN (1-2506): 0: 1884: 100.00
+	Hs
		139756 JAG2_HUMAN (425-671): 5.55e-20: 98.4: 17.32		CAC1A_HUMAN (1-2506): 0: 1884: 100.00
+	Hs
		139684 FBLN1_HUMAN (526-670): 5.64e-18: 90.9: 29.30		CAC1A_HUMAN (1-2506): 0: 1884: 100.00
+	Hs
		139668 MEGF6_HUMAN (258-667): 2.72e-15: 83.2: 18.14		CAC1A_HUMAN (1-2506): 0: 1884: 100.00
+	Hs
		139708 LTBP1_HUMAN (170-609): 8e-11: 68.4: 13.60		CAC1A_HUMAN (1-2506): 0: 1884: 100.00
+	Hs
		139726 LTBP4_HUMAN (222-607): 2.1e-10: 67.2: 16.82		CAC1A_HUMAN (1-2506): 0: 1884: 100.00
+	Hs
		85479 B7ZLY3_HUMAN (166-609): 1.72e-09: 64.2: 13.49		CAC1A_HUMAN (1-2506): 0: 1884: 100.00
+	Dm
		451759 NOTCH_DROME (173-550): 2.11e-15: 83.5: 12.56		CAC1D_DROME (1176-1542): 4.55e-38: 160: 21.95