HitPredict

Interactor 1: CNNM3 (Q8NE01)
Metal transporter CNNM3 (Ancient conserved domain-containing protein 3) (Cyclin-M3)
Gene: CNNM3

Interactor 2: TP4A1 (Q93096)
Protein tyrosine phosphatase type IVA 1 (EC 3.1.3.48) (PTP(CAAXI)) (Protein-tyrosine phosphatase 4a1) (Protein-tyrosine phosphatase of regenerating liver 1) (PRL-1)
Gene: PTP4A1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.89	0.80	0.847

Property	Details
Experiments	24632616, 27880917, 27432908, 28330616, 33961781, unassigned3799
Identification Methods	affinity chromatography technology, proximity labelling technology, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	CBS~Tc-R-P
Common GO terms	-
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 707 Hs			1 173
+	Hs
		277380 CNNM3_HUMAN (1-707): 0: 909: 100.00		TP4A3_HUMAN (1-172): 1.43e-56: 177: 79.07
+	Hs
		1091825 CNNM3_HUMAN (1-707): 0: 909: 100.00		TP4A2_HUMAN (4-173): 1.1e-54: 172: 87.65
+	Hs
		1224865 CNNM3_HUMAN (1-707): 0: 909: 100.00		TENS2_HUMAN (4-168): 1.46e-42: 152: 12.09
+	Hs
		1372473 CNNM2_HUMAN (131-691): 0: 703: 48.32		TP4A1_HUMAN (1-173): 9.55e-61: 187: 100.00
+	Hs
		1242457 CNNM4_HUMAN (114-691): 0: 696: 47.91		TP4A1_HUMAN (1-173): 9.55e-61: 187: 100.00
+	Hs
		1091840 CNNM2_HUMAN (131-691): 0: 703: 48.32		TP4A2_HUMAN (4-173): 1.1e-54: 172: 87.65
+	Hs
		1091816 CNNM4_HUMAN (114-691): 0: 696: 47.91		TP4A2_HUMAN (4-173): 1.1e-54: 172: 87.65
+	Hs
		1372475 CNNM1_HUMAN (150-705): 0: 610: 47.11		TP4A1_HUMAN (1-173): 9.55e-61: 187: 100.00
+	Hs
		1091843 CNNM1_HUMAN (150-705): 0: 610: 47.11		TP4A2_HUMAN (4-173): 1.1e-54: 172: 87.65
+	Dm
		2782 UEX_DROME (129-694): 0: 624: 37.29		PRL1_DROME (6-173): 1.24e-48: 157: 57.74