Protein: GGH
Gamma-glutamyl hydrolase (EC 3.4.19.9) (Conjugase) (GH) (Gamma-Glu-X carboxypeptidase)

Gene: GGH
Organism: Homo sapiens
Interactions: 233
UniProt ID: Q92820

Gene Ontology (top 5):
GO:0005576 - extracellular region
GO:0005615 - extracellular space
GO:0005634 - nucleus
GO:0005773 - vacuole
GO:0008238 - exopeptidase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

654631

CALX
Calnexin

3

1

High-throughput

0.667

High

238806

UGDH
UDP-glucose 6-dehydrogenase

3

0

High-throughput

0.638

High

419228

ITAV
Integrin alpha-V

2

2

High-throughput

0.628

High

205784

TGON2
Trans-Golgi network integral membrane protein 2

3

1

High-throughput

0.599

High

531931

PDIA4
Protein disulfide-isomerase A4

2

0

High-throughput

0.585

High

1100246

MICA
MHC class I polypeptide-related sequence A

2

0

High-throughput

0.585

High

1135823

DCAF8
DDB1- and CUL4-associated factor 8

2

0

High-throughput

0.585

High

1271370

TXD16
Thioredoxin domain-containing protein 16

2

0

High-throughput

0.585

High

1271335

SGTB
Small glutamine-rich tetratricopeptide repeat-containing protein beta

2

2

High-throughput

0.553

High

1271329

GGH
Gamma-glutamyl hydrolase

1

0

Small-scale

0.546

High

135823

MA2B1
Lysosomal alpha-mannosidase

1

2

High-throughput

0.536

High

152018

TOR1A
Torsin-1A

1

1

High-throughput

0.536

High

152097

TOR1B
Torsin-1B

1

1

High-throughput

0.536

High

165232

PLXB2
Plexin-B2

1

4

High-throughput

0.536

High

172695

LAMA5
Laminin subunit alpha-5

1

4

High-throughput

0.536

High

195984

PLXB1
Plexin-B1

1

5

High-throughput

0.536

High

276944

ATRN
Attractin

1

5

High-throughput

0.536

High

299574

LRIG2
Leucine-rich repeats and immunoglobulin-like domains protein 2

1

1

High-throughput

0.536

High

302419

CSTN1
Calsyntenin-1

1

1

High-throughput

0.536

High

351434

TGFB1
Transforming growth factor beta-1 proprotein [Cleaved into: Latency-associated peptide

1

1

High-throughput

0.536

High

433180

LAMB1
Laminin subunit beta-1

1

4

High-throughput

0.536

High

437689

BGLR
Beta-glucuronidase

1

1

High-throughput

0.536

High

502859

LAMC1
Laminin subunit gamma-1

1

4

High-throughput

0.536

High

550474

ARSB
Arylsulfatase B

1

3

High-throughput

0.536

High

557219

PGFRA
Platelet-derived growth factor receptor alpha

1

3

High-throughput

0.536

High

608073

FGFR4
Fibroblast growth factor receptor 4

1

3

High-throughput

0.536

High

609456

FGFR3
Fibroblast growth factor receptor 3

1

3

High-throughput

0.536

High

653681

CALR
Calreticulin

1

1

High-throughput

0.536

High

664187

PCSK6
Proprotein convertase subtilisin/kexin type 6

1

7

High-throughput

0.536

High

709270

GALNS
N-acetylgalactosamine-6-sulfatase

1

3

High-throughput

0.536

High

849843

SPHM
N-sulphoglucosamine sulphohydrolase

1

3

High-throughput

0.536

High

877436

LAMB2
Laminin subunit beta-2

1

4

High-throughput

0.536

High

990591

CKAP4
Cytoskeleton-associated protein 4

1

1

High-throughput

0.536

High

1016542

HYAL1
Hyaluronidase-1

1

1

High-throughput

0.536

High

1027978

SEM3B
Semaphorin-3B

1

1

High-throughput

0.536

High

1028089

DNJC3
DnaJ homolog subfamily C member 3

1

3

High-throughput

0.536

High

1034715

ADAM9
Disintegrin and metalloproteinase domain-containing protein 9

1

1

High-throughput

0.536

High

1034950

FKBP5
Peptidyl-prolyl cis-trans isomerase FKBP5

1

2

High-throughput

0.536

High

1045092

LAMB3
Laminin subunit beta-3

1

4

High-throughput

0.536

High

1053523

GAS6
Growth arrest-specific protein 6

1

1

High-throughput

0.536

High

1078480

TOM34
Mitochondrial import receptor subunit TOM34

1

3

High-throughput

0.536

High

1102937

QRIC1
Transcriptional regulator QRICH1

1

1

High-throughput

0.536

High

1165027

CSPG4
Chondroitin sulfate proteoglycan 4

1

2

High-throughput

0.536

High

1165658

ARSK
Arylsulfatase K

1

3

High-throughput

0.536

High

1166600

CREL2
Protein disulfide isomerase CRELD2

1

2

High-throughput

0.536

High

1191312

BMP8A
Bone morphogenetic protein 8A

1

1

High-throughput

0.536

High

1193255

MEGF8
Multiple epidermal growth factor-like domains protein 8

1

6

High-throughput

0.536

High

1240193

PCSK9
Proprotein convertase subtilisin/kexin type 9

1

2

High-throughput

0.536

High

1268525

PXDN
Peroxidasin homolog

1

1

High-throughput

0.536

High

1271357

CHRD
Chordin

1

6

High-throughput

0.536

High

1271374

PLXA1
Plexin-A1

1

4

High-throughput

0.536

High

1271375

GNPTG
N-acetylglucosamine-1-phosphotransferase subunit gamma

1

1

High-throughput

0.536

High

1271380

MA2B2
Epididymis-specific alpha-mannosidase

1

2

High-throughput

0.536

High

1271384

AGRG1
Adhesion G-protein coupled receptor G1

1

2

High-throughput

0.536

High

836860

DNLI4
DNA ligase 4

1

0

High-throughput

0.529

High

177959

TMPS2
Transmembrane protease serine 2

1

2

High-throughput

0.515

High

170438

TIF1A
Transcription intermediary factor 1-alpha

1

0

High-throughput

0.513

High

265786

CRLF1
Cytokine receptor-like factor 1

1

0

High-throughput

0.513

High

270318

LRP6
Low-density lipoprotein receptor-related protein 6

1

0

High-throughput

0.513

High

270432

KS6A5
Ribosomal protein S6 kinase alpha-5

1

0

High-throughput

0.513

High

270689

MYCB2
E3 ubiquitin-protein ligase MYCBP2

1

0

High-throughput

0.513

High

298689

UFL1
E3 UFM1-protein ligase 1

1

0

High-throughput

0.513

High

320556

OXSR1
Serine/threonine-protein kinase OSR1

1

0

High-throughput

0.513

High

327299

NOE2
Noelin-2

1

0

High-throughput

0.513

High

344803

TIMP1
Metalloproteinase inhibitor 1

1

0

High-throughput

0.513

High

438825

SRPRA
Signal recognition particle receptor subunit alpha

1

0

High-throughput

0.513

High

441629

TRFM
Melanotransferrin

1

0

High-throughput

0.513

High

502393

BIP
Endoplasmic reticulum chaperone BiP

1

0

High-throughput

0.513

High

518027

CO6A2

1

0

High-throughput

0.513

High

528120

BMP1
Bone morphogenetic protein 1

1

0

High-throughput

0.513

High

530382

CSPG2
Versican core protein

1

0

High-throughput

0.513

High

536183

PERF
Perforin-1

1

0

High-throughput

0.513

High

587655

NFKB1
Nuclear factor NF-kappa-B p105 subunit

1

0

High-throughput

0.513

High

723777

IDUA
Alpha-L-iduronidase

1

0

High-throughput

0.513

High

739600

SCNNA
Amiloride-sensitive sodium channel subunit alpha

1

0

High-throughput

0.513

High

786401

STAT1
Signal transducer and activator of transcription 1-alpha/beta

1

0

High-throughput

0.513

High

821881

HSP13
Heat shock 70 kDa protein 13

1

0

High-throughput

0.513

High

834555

FHIT
Bis(5'-adenosyl)-triphosphatase

1

0

High-throughput

0.513

High

872954

ANAG
Alpha-N-acetylglucosaminidase

1

0

High-throughput

0.513

High

959575

VIGLN
Vigilin

1

0

High-throughput

0.513

High

968890

NAAA
N-acylethanolamine-hydrolyzing acid amidase

1

0

High-throughput

0.513

High

1033621

MSLN
Mesothelin

1

0

High-throughput

0.513

High

1048509

DAG1
Dystroglycan 1

1

0

High-throughput

0.513

High

1050376

TTL12
Tubulin--tyrosine ligase-like protein 12

1

0

High-throughput

0.513

High

1056606

TRIPC
E3 ubiquitin-protein ligase TRIP12

1

0

High-throughput

0.513

High

1145099

METRL
Meteorin-like protein

1

0

High-throughput

0.513

High

1149932

KDM4D
Lysine-specific demethylase 4D

1

0

High-throughput

0.513

High

1168364

THSD4
Thrombospondin type-1 domain-containing protein 4

1

0

High-throughput

0.513

High

1202807

JAZF1
Juxtaposed with another zinc finger protein 1

1

0

High-throughput

0.513

High

1240622

UXS1
UDP-glucuronic acid decarboxylase 1

1

0

High-throughput

0.513

High

1241339

PAG15
Lysosomal phospholipase A and acyltransferase

1

0

High-throughput

0.513

High

1241489

CHSTE
Carbohydrate sulfotransferase 14

1

0

High-throughput

0.513

High

1255562

NEK7
Serine/threonine-protein kinase Nek7

1

0

High-throughput

0.513

High

1264415

CTBL1
Beta-catenin-like protein 1

1

0

High-throughput

0.513

High

1271330

CSN5
COP9 signalosome complex subunit 5

1

0

High-throughput

0.513

High

1271331

EXT2
Exostosin-2

1

0

High-throughput

0.513

High

1271333

PBIP1
Pre-B-cell leukemia transcription factor-interacting protein 1

1

0

High-throughput

0.513

High

1271336

I17RA
Interleukin-17 receptor A

1

0

High-throughput

0.513

High

1271337

VCIP1
Deubiquitinating protein VCPIP1

1

0

High-throughput

0.513

High

1271338

TOPK
Lymphokine-activated killer T-cell-originated protein kinase

1

0

High-throughput

0.513

High

1271339

NAR5
Ecto-ADP-ribosyltransferase 5

1

0

High-throughput

0.513

High

1271342

RPR1A
Regulation of nuclear pre-mRNA domain-containing protein 1A

1

0

High-throughput

0.513

High

1271348

CND3
Condensin complex subunit 3

1

0

High-throughput

0.513

High

1271352

CHID1
Chitinase domain-containing protein 1

1

0

High-throughput

0.513

High

1271371

ANFY1
Rabankyrin-5

1

0

High-throughput

0.513

High

1271379

HPSE
Heparanase

1

0

High-throughput

0.513

High

1271381

RRP44
Exosome complex exonuclease RRP44

1

0

High-throughput

0.513

High

1271382

LOXL2
Lysyl oxidase homolog 2

1

0

High-throughput

0.513

High

1271383

HYOU1
Hypoxia up-regulated protein 1

1

0

High-throughput

0.513

High

411460

INSR
Insulin receptor

1

4

High-throughput

0.500

High

994271

DHX9
ATP-dependent RNA helicase A

1

0

High-throughput

0.493

High

1117680

ARI4B
AT-rich interactive domain-containing protein 4B

1

0

High-throughput

0.493

High

1153207

ZN770
Zinc finger protein 770

1

0

High-throughput

0.493

High

1160879

FXL19
F-box/LRR-repeat protein 19

1

0

High-throughput

0.493

High

129498

MANBA
Beta-mannosidase

1

1

High-throughput

0.489

High

167591

IKKA
Inhibitor of nuclear factor kappa-B kinase subunit alpha

1

1

High-throughput

0.489

High

830096

MA2A2
Alpha-mannosidase 2x

1

2

High-throughput

0.489

High

850490

PLXA3
Plexin-A3

1

5

High-throughput

0.489

High

935954

NOMO3
BOS complex subunit NOMO3

1

1

High-throughput

0.489

High

1019230

HYAL2
Hyaluronidase-2

1

1

High-throughput

0.489

High

1044842

ITA7
Integrin alpha-7 [Cleaved into: Integrin alpha-7 heavy chain; Integrin alpha-7 light chain; Integrin alpha-7 70 kDa form]

1

2

High-throughput

0.489

High

1053110

FKBP8
Peptidyl-prolyl cis-trans isomerase FKBP8

1

1

High-throughput

0.489

High

1055302

PDIA5
Protein disulfide-isomerase A5

1

1

High-throughput

0.489

High

1058616

MBTP1
Membrane-bound transcription factor site-1 protease

1

2

High-throughput

0.489

High

1069034

NOMO1
BOS complex subunit NOMO1

1

1

High-throughput

0.489

High

1127283

TGO1
Transport and Golgi organization protein 1 homolog

1

1

High-throughput

0.489

High

1129475

EOGT
EGF domain-specific O-linked N-acetylglucosamine transferase

1

1

High-throughput

0.489

High

1147584

SE1L3
Protein sel-1 homolog 3

1

1

High-throughput

0.489

High

1165118

PLGT2
Protein O-glucosyltransferase 2

1

1

High-throughput

0.489

High

1173499

TMTC3
Protein O-mannosyl-transferase TMTC3

1

2

High-throughput

0.489

High

1204942

FRAS1
Extracellular matrix organizing protein FRAS1

1

5

High-throughput

0.489

High

1217658

P3H3
Prolyl 3-hydroxylase 3

1

1

High-throughput

0.489

High

1223955

CHSS2
Chondroitin sulfate synthase 2

1

1

High-throughput

0.489

High

1232157

TMTC2
Protein O-mannosyl-transferase TMTC2

1

2

High-throughput

0.489

High

1232242

EH1L1
EH domain-binding protein 1-like protein 1

1

1

High-throughput

0.489

High

1239195

PMGT2
Protein O-linked-mannose beta-1,4-N-acetylglucosaminyltransferase 2

1

1

High-throughput

0.489

High

1240000

PGLT1
Protein O-glucosyltransferase 1

1

1

High-throughput

0.489

High

1240159

TTC13
Tetratricopeptide repeat protein 13

1

3

High-throughput

0.489

High

1270742

SC65
Endoplasmic reticulum protein SC65

1

1

High-throughput

0.489

High

1271334

FKB10
Peptidyl-prolyl cis-trans isomerase FKBP10

1

2

High-throughput

0.489

High

1271349

LRFN3
Leucine-rich repeat and fibronectin type-III domain-containing protein 3

1

2

High-throughput

0.489

High

1271351

EDEM2
ER degradation-enhancing alpha-mannosidase-like protein 2

1

1

High-throughput

0.489

High

1271353

EDEM3
ER degradation-enhancing alpha-mannosidase-like protein 3

1

1

High-throughput

0.489

High

1271362

SEM4G
Semaphorin-4G

1

2

High-throughput

0.489

High

1271363

FKB14
Peptidyl-prolyl cis-trans isomerase FKBP14

1

2

High-throughput

0.489

High

1271369

CHPF2
Chondroitin sulfate glucuronyltransferase

1

1

High-throughput

0.489

High

1271376

ADA21
Disintegrin and metalloproteinase domain-containing protein 21

1

1

High-throughput

0.489

High

1271378

ICAM5
Intercellular adhesion molecule 5

1

1

High-throughput

0.489

High

338793

EGFR
Epidermal growth factor receptor

1

2

High-throughput

0.479

High

643379

HMGB2
High mobility group protein B2

1

1

High-throughput

0.479

High

1051243

ZMYM3
Zinc finger MYM-type protein 3

1

1

High-throughput

0.479

High

1198118

TM11B
Transmembrane protease serine 11B

1

2

High-throughput

0.479

High

1263683

AGRV1
Adhesion G-protein coupled receptor V1

1

3

High-throughput

0.479

High

1271361

TMPS4
Transmembrane protease serine 4

1

2

High-throughput

0.479

High

1271368

PD1L1
Programmed cell death 1 ligand 1

1

2

High-throughput

0.479

High

211638

ACTN4
Alpha-actinin-4

1

0

High-throughput

0.458

High

547351

VATB1
V-type proton ATPase subunit B, kidney isoform

1

0

High-throughput

0.458

High

553339

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.458

High

569927

CEBPB
CCAAT/enhancer-binding protein beta

1

0

High-throughput

0.458

High

651851

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.458

High

670144

MARCS
Myristoylated alanine-rich C-kinase substrate

1

0

High-throughput

0.458

High

683601

1433B
14-3-3 protein beta/alpha

1

0

High-throughput

0.458

High

713567

GLYM
Serine hydroxymethyltransferase, mitochondrial

1

0

High-throughput

0.458

High

779842

CCNF
Cyclin-F

1

0

High-throughput

0.458

High

818319

SOX2
Transcription factor SOX-2

1

0

High-throughput

0.458

High

832618

MCM2
DNA replication licensing factor MCM2

1

0

High-throughput

0.458

High

875179

TERA
Transitional endoplasmic reticulum ATPase

1

0

High-throughput

0.458

High

880985

IF6
Eukaryotic translation initiation factor 6

1

0

High-throughput

0.458

High

902698

SUMO2
Small ubiquitin-related modifier 2

1

0

High-throughput

0.458

High

966858

AT2B2
Plasma membrane calcium-transporting ATPase 2

1

0

High-throughput

0.458

High

1239703

NHLC2
NHL repeat-containing protein 2

1

0

High-throughput

0.458

High

1271344

RANB9
Ran-binding protein 9

1

0

Small-scale

0.458

High

1271359

BRD7
Bromodomain-containing protein 7

1

0

High-throughput

0.458

High

1271372

LRWD1
Leucine-rich repeat and WD repeat-containing protein 1

1

0

High-throughput

0.458

High

435715

IGF1R
Insulin-like growth factor 1 receptor

1

4

High-throughput

0.457

High

1081557

NTRK3
NT-3 growth factor receptor

1

5

High-throughput

0.457

High

385282

NTRK1
High affinity nerve growth factor receptor

1

5

High-throughput

0.437

High

750879

VATA
V-type proton ATPase catalytic subunit A

1

0

High-throughput

0.426

High

1153316

PKHA7
Pleckstrin homology domain-containing family A member 7

1

0

High-throughput

0.426

High

1271343

MIA2
Melanoma inhibitory activity protein 2

1

1

High-throughput

0.407

High

1034507

OS9
Protein OS-9

3

0

High-throughput

0.347

High

1133320

GT253
Inactive glycosyltransferase 25 family member 3

3

0

High-throughput

0.347

High

1271377

MKLN1
Muskelin

3

0

High-throughput

0.347

High

164141

ARHGA
Rho guanine nucleotide exchange factor 10

1

0

High-throughput

0.279

Low

182284

TPSN
Tapasin

1

0

High-throughput

0.279

Low

233079

FZD6
Frizzled-6

1

0

High-throughput

0.279

Low

299781

PLPHP
Pyridoxal phosphate homeostasis protein

1

0

High-throughput

0.279

Low

315470

G6PE
GDH/6PGL endoplasmic bifunctional protein [Includes: Hexose-6-phosphate dehydrogenase

1

0

High-throughput

0.279

Low

330505

CLPT1
Putative lipid scramblase CLPTM1

1

0

High-throughput

0.279

Low

335293

DYR
Dihydrofolate reductase

1

0

High-throughput

0.279

Low

355048

DQB1
HLA class II histocompatibility antigen, DQ beta 1 chain

1

0

High-throughput

0.279

Low

573836

PTN1
Tyrosine-protein phosphatase non-receptor type 1

1

0

High-throughput

0.279

Low

674223

HMOX2
Heme oxygenase 2

1

0

High-throughput

0.279

Low

674618

ACHA5
Neuronal acetylcholine receptor subunit alpha-5

1

0

High-throughput

0.279

Low

942014

IF4G2
Eukaryotic translation initiation factor 4 gamma 2

1

0

High-throughput

0.279

Low

1040195

STIM1
Stromal interaction molecule 1

1

0

High-throughput

0.279

Low

1061945

GAPD1
GTPase-activating protein and VPS9 domain-containing protein 1

1

0

High-throughput

0.279

Low

1115423

FUT11
Alpha-(1,3)-fucosyltransferase 11

1

0

High-throughput

0.279

Low

1138451

CAHD1
VWFA and cache domain-containing protein 1

1

0

High-throughput

0.279

Low

1160427

PDXD1
Pyridoxal-dependent decarboxylase domain-containing protein 1

1

0

High-throughput

0.279

Low

1160489

GLT18
Polypeptide N-acetylgalactosaminyltransferase 18

1

0

High-throughput

0.279

Low

1218612

FXRD2
FAD-dependent oxidoreductase domain-containing protein 2

1

0

High-throughput

0.279

Low

1218869

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

0

High-throughput

0.279

Low

1239984

SUMF1
Formylglycine-generating enzyme

1

0

High-throughput

0.279

Low

1241300

CAMKV
CaM kinase-like vesicle-associated protein

1

0

High-throughput

0.279

Low

1253234

RDH11
Retinol dehydrogenase 11

1

0

High-throughput

0.279

Low

1256150

GPX8
Probable glutathione peroxidase 8

1

0

High-throughput

0.279

Low

1266821

TM131
Transmembrane protein 131

1

0

High-throughput

0.279

Low

1271332

TTC17
Tetratricopeptide repeat protein 17

1

0

High-throughput

0.279

Low

1271340

H6ST2
Heparan-sulfate 6-O-sulfotransferase 2

1

0

High-throughput

0.279

Low

1271347

PLCA
1-acyl-sn-glycerol-3-phosphate acyltransferase alpha

1

0

High-throughput

0.279

Low

1271350

TMM43
Transmembrane protein 43

1

0

High-throughput

0.279

Low

1271356

UN93B
Protein unc-93 homolog B1

1

0

High-throughput

0.279

Low

1271358

SG196
Protein O-mannose kinase

1

0

High-throughput

0.279

Low

1271364

P4HTM
Transmembrane prolyl 4-hydroxylase

1

0

High-throughput

0.279

Low

1271365

B3GN2
N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 2

1

0

High-throughput

0.279

Low

1271366

CELR1
Cadherin EGF LAG seven-pass G-type receptor 1

1

0

High-throughput

0.279

Low

1271367

UGGG2
UDP-glucose:glycoprotein glucosyltransferase 2

1

0

High-throughput

0.279

Low

1271373

SUN2
SUN domain-containing protein 2

1

0

High-throughput

0.279

Low

391071

RPN2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

1

0

High-throughput

0.249

Low

670989

PRDX3
Thioredoxin-dependent peroxide reductase, mitochondrial

1

0

High-throughput

0.249

Low

890312

SC61B
Protein transport protein Sec61 subunit beta

1

0

High-throughput

0.249

Low

1171072

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.249

Low

1222674

TM192
Transmembrane protein 192

1

0

High-throughput

0.249

Low

1271345

RUFY1
RUN and FYVE domain-containing protein 1

1

0

High-throughput

0.249

Low

1271346

ACON
Aconitate hydratase, mitochondrial

1

0

High-throughput

0.249

Low

1271355

DDX24
ATP-dependent RNA helicase DDX24

1

0

High-throughput

0.249

Low

1271360

FBX6
F-box only protein 6

1

0

High-throughput

0.249

Low

200645

CP110
Centriolar coiled-coil protein of 110 kDa

1

0

High-throughput

0.232

Low

1238936

POC5
Centrosomal protein POC5

1

0

High-throughput

0.232

Low

1271341

CEP63
Centrosomal protein of 63 kDa

1

0

High-throughput

0.232

Low

1271354

MLP3B
Microtubule-associated proteins 1A/1B light chain 3B

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024