Protein: CNNM4
Metal transporter CNNM4 (Ancient conserved domain-containing protein 4) (Cyclin-M4)

Gene: CNNM4
Organism: Homo sapiens
Interactions: 70
UniProt ID: Q6P4Q7

Gene Ontology (top 5):
GO:0005886 - plasma membrane
GO:0007601 - visual perception
GO:0010960 - magnesium ion homeostasis
GO:0015081 - sodium ion transmembrane transporter activity
GO:0015095 - magnesium ion transmembrane transporter activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1091816

TP4A2
Protein tyrosine phosphatase type IVA 2

7

10

High-throughput

0.967

High

1242457

TP4A1
Protein tyrosine phosphatase type IVA 1

6

10

High-throughput

0.847

High

1242468

ARL15
ADP-ribosylation factor-like protein 15

3

5

High-throughput

0.765

High

1242472

BTNL2
Butyrophilin-like protein 2

1

3

High-throughput

0.691

High

845684

MUC18
Cell surface glycoprotein MUC18

1

1

High-throughput

0.618

High

1163776

PTPRO
Receptor-type tyrosine-protein phosphatase O

1

0

High-throughput

0.586

High

1242463

UN93B
Protein unc-93 homolog B1

2

1

High-throughput

0.549

High

139240

UPK2
Uroplakin-2

1

2

High-throughput

0.536

High

349451

TSN15
Tetraspanin-15

1

4

High-throughput

0.536

High

351912

S1PR4
Sphingosine 1-phosphate receptor 4

1

8

High-throughput

0.536

High

380305

DRA
HLA class II histocompatibility antigen, DR alpha chain

1

9

High-throughput

0.536

High

380637

DQB1
HLA class II histocompatibility antigen, DQ beta 1 chain

1

9

High-throughput

0.536

High

480827

LEG1
Galectin-1

1

1

High-throughput

0.536

High

564917

ICAM2
Intercellular adhesion molecule 2

1

1

High-throughput

0.536

High

607381

HLAG
HLA class I histocompatibility antigen, alpha chain G

1

3

High-throughput

0.536

High

638201

S1PR1
Sphingosine 1-phosphate receptor 1

1

5

High-throughput

0.536

High

820559

GPV
Platelet glycoprotein V

1

1

High-throughput

0.536

High

935381

IOD3
Thyroxine 5-deiodinase

1

1

High-throughput

0.536

High

1098905

KLRD1
Natural killer cells antigen CD94

1

5

High-throughput

0.536

High

1142086

P2RY6
P2Y purinoceptor 6

1

1

High-throughput

0.536

High

1242464

LPAR2
Lysophosphatidic acid receptor 2

1

5

High-throughput

0.536

High

1242467

GP173
Probable G-protein coupled receptor 173

1

1

High-throughput

0.536

High

1242470

CLC2D
C-type lectin domain family 2 member D

1

5

High-throughput

0.536

High

1242466

TMPS4
Transmembrane protease serine 4

1

5

High-throughput

0.515

High

230974

TYOBP
TYRO protein tyrosine kinase-binding protein

1

0

High-throughput

0.513

High

291818

STK16
Serine/threonine-protein kinase 16

1

0

High-throughput

0.513

High

833470

WNT5A
Protein Wnt-5a

1

0

High-throughput

0.513

High

1113426

CUL3
Cullin-3

1

0

High-throughput

0.513

High

1228750

MBLC2
Acyl-coenzyme A thioesterase MBLAC2

1

0

High-throughput

0.513

High

1242459

T106A
Transmembrane protein 106A

1

0

High-throughput

0.513

High

1242461

SGCZ
Zeta-sarcoglycan

1

0

High-throughput

0.513

High

1055062

TYRO3
Tyrosine-protein kinase receptor TYRO3

1

6

High-throughput

0.500

High

219317

B4GA1
Beta-1,4-glucuronyltransferase 1

1

1

High-throughput

0.489

High

342588

LY86
Lymphocyte antigen 86

1

1

High-throughput

0.489

High

548038

PSPC
Surfactant protein C

1

2

High-throughput

0.489

High

634769

GRAH
Granzyme H

1

1

High-throughput

0.489

High

1242451

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

1

High-throughput

0.489

High

1242469

KLK14
Kallikrein-14

1

1

High-throughput

0.489

High

375627

RASK
GTPase KRas

1

7

High-throughput

0.479

High

693004

DPP4
Dipeptidyl peptidase 4

1

1

High-throughput

0.479

High

978095

RHOB
Rho-related GTP-binding protein RhoB

1

10

High-throughput

0.479

High

1116222

PTC1
Protein patched homolog 1

1

3

High-throughput

0.479

High

1144966

RAB35
Ras-related protein Rab-35

1

2

High-throughput

0.479

High

1242448

LMBRL
Protein LMBR1L

1

1

High-throughput

0.479

High

1242450

TM11B
Transmembrane protease serine 11B

1

5

High-throughput

0.479

High

1242471

S12A6
Solute carrier family 12 member 6

1

0

Small-scale

0.458

High

641960

CD9
CD9 antigen

1

4

High-throughput

0.445

High

1090026

NTCP2
Ileal sodium/bile acid cotransporter

1

1

High-throughput

0.445

High

1242455

LPAR1
Lysophosphatidic acid receptor 1

1

5

High-throughput

0.445

High

1242462

S22A4
Solute carrier family 22 member 4

1

11

High-throughput

0.445

High

1242473

S22AE
Solute carrier family 22 member 14

1

11

High-throughput

0.445

High

125505

LEG9
Galectin-9

1

1

High-throughput

0.437

High

293868

CD123
Translation initiation factor eIF2 assembly protein

1

2

High-throughput

0.437

High

830936

CCNF
Cyclin-F

1

2

High-throughput

0.437

High

1242458

CK052
Uncharacterized protein C11orf52

1

1

High-throughput

0.437

High

255079

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

0

High-throughput

0.426

High

934752

TERA
Transitional endoplasmic reticulum ATPase

1

0

High-throughput

0.426

High

1242449

NIPA1
Magnesium transporter NIPA1

1

0

High-throughput

0.426

High

1242453

MOT10
Monocarboxylate transporter 10

1

0

High-throughput

0.426

High

1242452

S35F3
Solute carrier family 35 member F3

1

1

High-throughput

0.407

High

1242460

LRC39
Leucine-rich repeat-containing protein 39

3

0

High-throughput

0.347

High

933184

SLUR1
Secreted Ly-6/uPAR-related protein 1

1

0

High-throughput

0.279

Low

1140088

IQCB1
IQ calmodulin-binding motif-containing protein 1

1

0

High-throughput

0.279

Low

1239223

ARMC6
Armadillo repeat-containing protein 6

1

0

High-throughput

0.279

Low

1242454

KCNE4
Potassium voltage-gated channel subfamily E member 4

1

0

High-throughput

0.279

Low

194239

R113A
E3 ubiquitin-protein ligase RNF113A

1

0

High-throughput

0.249

Low

1199792

AGK
Acylglycerol kinase, mitochondrial

1

0

Small-scale

0.249

Low

1242456

ESR2
Estrogen receptor beta

1

0

High-throughput

0.249

Low

1178805

KIZ
Centrosomal protein kizuna

1

0

High-throughput

0.232

Low

1242465

RT30
Large ribosomal subunit protein mL65

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025