HitPredict

Interactor 1: TP4A1 (Q93096)
Protein tyrosine phosphatase type IVA 1 (EC 3.1.3.48) (PTP(CAAXI)) (Protein-tyrosine phosphatase 4a1) (Protein-tyrosine phosphatase of regenerating liver 1) (PRL-1)
Gene: PTP4A1

Interactor 2: CNNM2 (Q9H8M5)
Metal transporter CNNM2 (Ancient conserved domain-containing protein 2) (Cyclin-M2)
Gene: CNNM2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.80	0.770

Property	Details
Experiments	28330616, 33961781, unassigned3799
Identification Methods	affinity chromatography technology, proximity labelling technology, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	CBS~Tc-R-P
Common GO terms	-
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 173 Hs			1 875
+	Hs
		1091840 TP4A2_HUMAN (4-173): 1.1e-54: 172: 87.65		CNNM2_HUMAN (1-875): 0: 1254: 100.00
+	Hs
		1242457 TP4A1_HUMAN (1-173): 9.55e-61: 187: 100.00		CNNM4_HUMAN (60-867): 0: 922: 59.98
+	Hs
		1091816 TP4A2_HUMAN (4-173): 1.1e-54: 172: 87.65		CNNM4_HUMAN (60-867): 0: 922: 59.98
+	Hs
		1372475 TP4A1_HUMAN (1-173): 9.55e-61: 187: 100.00		CNNM1_HUMAN (74-866): 0: 839: 48.59
+	Hs
		1091843 TP4A2_HUMAN (4-173): 1.1e-54: 172: 87.65		CNNM1_HUMAN (74-866): 0: 839: 48.59
+	Dm
		2782 PRL1_DROME (6-173): 1.24e-48: 157: 57.74		UEX_DROME (74-871): 0: 689: 41.30
+	Hs
		1337044 TP4A1_HUMAN (1-173): 9.55e-61: 187: 100.00		CNNM3_HUMAN (276-865): 0: 572: 48.74
+	Hs
		277380 TP4A3_HUMAN (1-172): 1.43e-56: 177: 79.07		CNNM3_HUMAN (276-865): 0: 572: 48.74
+	Hs
		1091825 TP4A2_HUMAN (4-173): 1.1e-54: 172: 87.65		CNNM3_HUMAN (276-865): 0: 572: 48.74
+	Hs
		1224865 TENS2_HUMAN (4-168): 1.46e-42: 152: 12.09		CNNM3_HUMAN (276-865): 0: 572: 48.74