HitPredict

Interactor 1: PODXL (O00592)
Podocalyxin (GCTM-2 antigen) (Gp200) (Podocalyxin-like protein 1) (PC) (PCLP-1)
Gene: PODXL

Interactor 2: RAC1 (P63000)
Ras-related C3 botulinum toxin substrate 1 (EC 3.6.5.2) (Cell migration-inducing gene 5 protein) (Ras-like protein TC25) (p21-Rac1)
Gene: RAC1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005886 - plasma membrane GO:0007155 - cell adhesion GO:0016477 - cell migration GO:0030027 - lamellipodium and 1 others more... GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 558 Hs			1 192
+	Hs
		134441 PODXL_HUMAN (1-558): 6.78e-66: 225: 100.00		RAC2_HUMAN (1-192): 1.2e-82: 244: 92.19
+	Hs
		134490 PODXL_HUMAN (1-558): 6.78e-66: 225: 100.00		RHOJ_HUMAN (2-189): 1.38e-80: 240: 60.64
+	Hs
		134457 PODXL_HUMAN (1-558): 6.78e-66: 225: 100.00		RAC3_HUMAN (1-191): 2.72e-79: 236: 93.19
+	Hs
		134465 PODXL_HUMAN (1-558): 6.78e-66: 225: 100.00		RHOG_HUMAN (1-192): 3.1e-79: 236: 71.35
+	Hs
		134458 PODXL_HUMAN (1-558): 6.78e-66: 225: 100.00		CDC42_HUMAN (1-192): 1.4e-78: 234: 70.31
+	Hs
		134459 PODXL_HUMAN (1-558): 6.78e-66: 225: 100.00		RHOA_HUMAN (5-192): 3.5e-77: 230: 57.98
+	Hs
		134434 PODXL_HUMAN (1-558): 6.78e-66: 225: 100.00		RHOC_HUMAN (5-192): 8.68e-75: 224: 57.45
+	Hs
		297823 K0754_HUMAN (67-478): 2.12e-25: 113: 11.86		RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00
+	Hs
		297812 K0754_HUMAN (67-478): 2.12e-25: 113: 11.86		RAC2_HUMAN (1-192): 1.2e-82: 244: 92.19
+	Hs
		892632 PDXL2_HUMAN (29-558): 3.21e-28: 120: 18.38		RAC3_HUMAN (1-191): 2.72e-79: 236: 93.19
+	Hs
		951406 PDXL2_HUMAN (29-558): 3.21e-28: 120: 18.38		RHOG_HUMAN (1-192): 3.1e-79: 236: 71.35
+	Hs
		297840 K0754_HUMAN (67-478): 2.12e-25: 113: 11.86		RHOJ_HUMAN (2-189): 1.38e-80: 240: 60.64
+	Ce
		136793 UNC89_CAEEL (6-463): 7.48e-23: 105: 10.85		RAC1_CAEEL (1-192): 2.2e-83: 246: 82.81
+	Hs
		297819 K0754_HUMAN (67-478): 2.12e-25: 113: 11.86		RAC3_HUMAN (1-191): 2.72e-79: 236: 93.19
+	Hs
		297827 K0754_HUMAN (67-478): 2.12e-25: 113: 11.86		RHOG_HUMAN (1-192): 3.1e-79: 236: 71.35
+	Hs
		297820 K0754_HUMAN (67-478): 2.12e-25: 113: 11.86		RHOA_HUMAN (5-192): 3.5e-77: 230: 57.98
+	Ce
		104464 UNC89_CAEEL (6-463): 7.48e-23: 105: 10.85		G5EBV3_CAEEL (2-192): 6.22e-78: 232: 65.45
+	Hs
		297809 K0754_HUMAN (67-478): 2.12e-25: 113: 11.86		RHOC_HUMAN (5-192): 8.68e-75: 224: 57.45
+	Ce
		136794 UNC89_CAEEL (6-463): 7.48e-23: 105: 10.85		CDC42_CAEEL (1-192): 5.89e-76: 227: 69.27
+	Ce
		136800 UNC89_CAEEL (6-463): 7.48e-23: 105: 10.85		RHO1_CAEEL (5-192): 4.91e-75: 225: 59.04