Protein: PO2F1
POU domain, class 2, transcription factor 1 (NF-A1) (Octamer-binding protein 1) (Oct-1) (Octamer-binding transcription factor 1) (OTF-1)

Gene: PO2F1, POU2F1
Organism: Homo sapiens
Interactions: 158
UniProt ID: P14859

Gene Ontology (top 5):
GO:0000785 - chromatin
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000979 - RNA polymerase II core promoter sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

540769

PO2F1
POU domain, class 2, transcription factor 1

5

17

Small-scale

0.918

High

540852

OBF1
POU domain class 2-associating factor 1

4

1

Small-scale

0.871

High

540829

PO6F2
POU domain, class 6, transcription factor 2

2

18

High-throughput

0.783

High

540851

ZFHX3
Zinc finger homeobox protein 3

2

11

High-throughput

0.783

High

540806

SOX2
Transcription factor SOX-2

2

20

Small-scale

0.754

High

446889

HXC4
Homeobox protein Hox-C4

1

20

Small-scale

0.724

High

213295

TLX2
T-cell leukemia homeobox protein 2

1

20

High-throughput

0.698

High

540790

HXC9
Homeobox protein Hox-C9

1

20

High-throughput

0.698

High

540867

HXB13
Homeobox protein Hox-B13

1

20

High-throughput

0.698

High

377065

GCR
Glucocorticoid receptor

4

20

Small-scale

0.698

High

523491

XRCC6
X-ray repair cross-complementing protein 6

4

5

Small-scale

0.692

High

434919

SP1
Transcription factor Sp1

3

12

Small-scale

0.689

High

540801

PBX1
Pre-B-cell leukemia transcription factor 1

1

5

Small-scale

0.681

High

540815

PKNX1
Homeobox protein PKNOX1

1

5

Small-scale

0.681

High

524777

XRCC5
X-ray repair cross-complementing protein 5

4

5

Small-scale

0.676

High

540837

SP4
Transcription factor Sp4

3

9

High-throughput

0.675

High

540805

MAGAA
Melanoma-associated antigen 10

3

3

High-throughput

0.667

High

540885

NCOR2
Nuclear receptor corepressor 2

3

19

Small-scale

0.664

High

540810

HCFC1
Host cell factor 1

3

1

Small-scale

0.650

High

540799

BRCA1
Breast cancer type 1 susceptibility protein

3

2

Small-scale

0.640

High

361815

FIBB
Fibrinogen beta chain [Cleaved into: Fibrinopeptide B; Fibrinogen beta chain]

2

1

High-throughput

0.628

High

197658

CRX
Cone-rod homeobox protein

1

20

High-throughput

0.618

High

211789

TLX3
T-cell leukemia homeobox protein 3

1

20

High-throughput

0.618

High

225708

SOX15
Transcription factor SOX-15

1

20

High-throughput

0.618

High

540785

PAX7
Paired box protein Pax-7

1

20

High-throughput

0.618

High

540787

PAX6
Paired box protein Pax-6

1

20

High-throughput

0.618

High

540797

SOX5
Transcription factor SOX-5

1

20

High-throughput

0.618

High

540798

SOX6
Transcription factor SOX-6

1

20

High-throughput

0.618

High

540816

GSC
Homeobox protein goosecoid

1

20

High-throughput

0.618

High

540880

SOX17
Transcription factor SOX-17

1

20

High-throughput

0.618

High

321964

ZMYM6
Zinc finger MYM-type protein 6

2

3

High-throughput

0.606

High

540784

NFYA
Nuclear transcription factor Y subunit alpha

2

1

High-throughput

0.606

High

540807

ARRB1
Beta-arrestin-1

2

1

High-throughput

0.606

High

540814

AF10
Protein AF-10

2

4

High-throughput

0.606

High

540839

CREM
cAMP-responsive element modulator

2

4

High-throughput

0.606

High

540778

RXRA
Retinoic acid receptor RXR-alpha

2

20

Small-scale

0.602

High

540830

PRKDC
DNA-dependent protein kinase catalytic subunit

2

5

Small-scale

0.602

High

540779

TBP
TATA-box-binding protein

1

4

Small-scale

0.589

High

540834

PR20A
Proline-rich protein 20A

3

4

High-throughput

0.586

High

268387

BAF
Barrier-to-autointegration factor

2

0

Small-scale

0.585

High

540780

LMNB1
Lamin-B1

2

4

Small-scale

0.584

High

169028

ARPC3
Actin-related protein 2/3 complex subunit 3

2

0

High-throughput

0.580

High

540857

STOX1
Storkhead-box protein 1

2

0

High-throughput

0.580

High

540864

SNIP1
Smad nuclear-interacting protein 1

2

0

High-throughput

0.580

High

540870

ZC3HA
Zinc finger CCCH domain-containing protein 10

2

0

High-throughput

0.580

High

540854

SNPC4
snRNA-activating protein complex subunit 4

2

3

Small-scale

0.576

High

540860

POGZ
Pogo transposable element with ZNF domain

1

4

High-throughput

0.573

High

540879

PLK3
Serine/threonine-protein kinase PLK3

1

3

High-throughput

0.573

High

352470

TNFA
Tumor necrosis factor

2

0

Small-scale

0.569

High

381778

G3P
Glyceraldehyde-3-phosphate dehydrogenase

1

1

Small-scale

0.561

High

490085

COT1
COUP transcription factor 1

1

20

Small-scale

0.561

High

540772

CREB1
Cyclic AMP-responsive element-binding protein 1

1

2

Small-scale

0.561

High

540840

TF65
Transcription factor p65

1

6

Small-scale

0.561

High

200973

VIP2
Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2

2

1

High-throughput

0.553

High

455045

PARP1
Poly [ADP-ribose] polymerase 1

1

10

Small-scale

0.549

High

540836

IRF9
Interferon regulatory factor 9

1

4

High-throughput

0.541

High

540850

CEBPE
CCAAT/enhancer-binding protein epsilon

1

13

High-throughput

0.541

High

540774

HMGA1
High mobility group protein HMG-I/HMG-Y

1

3

Small-scale

0.536

High

127175

IPO5
Importin-5

1

3

High-throughput

0.536

High

208889

FOXS1
Forkhead box protein S1

1

18

High-throughput

0.536

High

503362

HSP7C
Heat shock cognate 71 kDa protein

1

3

High-throughput

0.536

High

540793

ARRB2
Beta-arrestin-2

1

1

High-throughput

0.536

High

540813

HSP72
Heat shock-related 70 kDa protein 2

1

3

High-throughput

0.536

High

540848

TEAD2
Transcriptional enhancer factor TEF-4

1

7

High-throughput

0.536

High

540875

FOXC2
Forkhead box protein C2

1

20

High-throughput

0.536

High

540812

MAT1
CDK-activating kinase assembly factor MAT1

1

2

Small-scale

0.527

High

540786

CCND1
G1/S-specific cyclin-D1

1

2

Small-scale

0.515

High

540858

Q7KZS0
SUMO-conjugating enzyme UBC9

1

4

High-throughput

0.515

High

540861

CKLF8
CKLF-like MARVEL transmembrane domain-containing protein 8

1

0

High-throughput

0.513

High

540871

PASK
PAS domain-containing serine/threonine-protein kinase

1

0

High-throughput

0.513

High

540874

BAG1
BAG family molecular chaperone regulator 1

1

0

High-throughput

0.513

High

540832

PR20E
Proline-rich protein 20E

2

4

High-throughput

0.504

High

368919

ESR1
Estrogen receptor

1

20

Small-scale

0.501

High

394049

A4
Amyloid-beta precursor protein

1

1

High-throughput

0.501

High

414432

PRGR
Progesterone receptor

1

20

Small-scale

0.501

High

487096

ANDR
Androgen receptor

1

20

Small-scale

0.501

High

487895

RARA
Retinoic acid receptor alpha

1

20

Small-scale

0.501

High

500385

THA
Thyroid hormone receptor alpha

1

20

Small-scale

0.501

High

509898

VDR
Vitamin D3 receptor

1

20

Small-scale

0.501

High

540775

KAPCA
cAMP-dependent protein kinase catalytic subunit alpha

1

1

Small-scale

0.501

High

540788

TEAD1
Transcriptional enhancer factor TEF-1

1

7

Small-scale

0.501

High

540853

TRXR1
Thioredoxin reductase 1, cytoplasmic

1

1

Small-scale

0.501

High

323570

BAG2
BAG family molecular chaperone regulator 2

1

1

High-throughput

0.489

High

540789

S10A2
Protein S100-A2

1

7

High-throughput

0.489

High

540878

LOXE3
Hydroperoxide isomerase ALOXE3

1

1

High-throughput

0.489

High

540771

ZEP1
Zinc finger protein 40

1

6

High-throughput

0.481

High

540824

UBC9
SUMO-conjugating enzyme UBC9

1

4

High-throughput

0.481

High

153554

ANM5
Protein arginine N-methyltransferase 5

1

1

Small-scale

0.479

High

316781

KLF8
Krueppel-like factor 8

1

13

High-throughput

0.479

High

391531

H2A1B
Histone H2A type 1-B/E

1

1

Small-scale

0.479

High

408992

K2C8
Keratin, type II cytoskeletal 8

1

3

Small-scale

0.479

High

415191

ATPB
ATP synthase subunit beta, mitochondrial

1

2

Small-scale

0.479

High

433554

LYN
Tyrosine-protein kinase Lyn

1

5

Small-scale

0.479

High

443122

NFIC
Nuclear factor 1 C-type

1

12

High-throughput

0.479

High

501631

BIP
Endoplasmic reticulum chaperone BiP

1

3

Small-scale

0.479

High

528471

CFTR
Cystic fibrosis transmembrane conductance regulator

1

1

Small-scale

0.479

High

537784

KPYM
Pyruvate kinase PKM

1

2

Small-scale

0.479

High

540770

ATF2
Cyclic AMP-dependent transcription factor ATF-2

1

9

Small-scale

0.479

High

540776

CEBPB
CCAAT/enhancer-binding protein beta

1

11

High-throughput

0.479

High

540777

RO52
E3 ubiquitin-protein ligase TRIM21

1

1

Small-scale

0.479

High

540781

CD11B
Cyclin-dependent kinase 11B

1

5

Small-scale

0.479

High

540791

HNRH1
Heterogeneous nuclear ribonucleoprotein H

1

3

Small-scale

0.479

High

540792

STIP1
Stress-induced-phosphoprotein 1

1

2

Small-scale

0.479

High

540795

HSP74
Heat shock 70 kDa protein 4

1

3

Small-scale

0.479

High

540802

STAT3
Signal transducer and activator of transcription 3

1

6

Small-scale

0.479

High

540803

ELK3
ETS domain-containing protein Elk-3

1

15

High-throughput

0.479

High

540804

STA5A
Signal transducer and activator of transcription 5A

1

6

Small-scale

0.479

High

540808

CEBPA
CCAAT/enhancer-binding protein alpha

1

11

High-throughput

0.479

High

540811

STA5B
Signal transducer and activator of transcription 5B

1

6

Small-scale

0.479

High

540818

HNRPK
Heterogeneous nuclear ribonucleoprotein K

1

2

Small-scale

0.479

High

540823

PPIA
Peptidyl-prolyl cis-trans isomerase A

1

2

Small-scale

0.479

High

540825

EF1A1
Elongation factor 1-alpha 1

1

1

Small-scale

0.479

High

540827

H31
Histone H3.1

1

9

High-throughput

0.479

High

540831

H33
Histone H3.3

1

9

High-throughput

0.479

High

540835

HNRPU
Heterogeneous nuclear ribonucleoprotein U

1

4

Small-scale

0.479

High

540838

PAX2
Paired box protein Pax-2

1

20

High-throughput

0.479

High

540842

FOXC1
Forkhead box protein C1

1

20

High-throughput

0.479

High

540843

FOXL1
Forkhead box protein L1

1

19

High-throughput

0.479

High

540844

HDAC1
Histone deacetylase 1

1

5

Small-scale

0.479

High

540846

IRF3
Interferon regulatory factor 3

1

4

Small-scale

0.479

High

540847

NFIX
Nuclear factor 1 X-type

1

14

High-throughput

0.479

High

540849

ELF2
ETS-related transcription factor Elf-2

1

12

High-throughput

0.479

High

540859

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

2

High-throughput

0.479

High

540863

KCD17
BTB/POZ domain-containing protein KCTD17

1

1

Small-scale

0.479

High

540866

SP7
Transcription factor Sp7

1

12

High-throughput

0.479

High

540872

FEV
Protein FEV

1

13

High-throughput

0.479

High

540877

KLF16
Krueppel-like factor 16

1

10

High-throughput

0.479

High

540882

ZRAN1
Ubiquitin thioesterase ZRANB1

1

3

High-throughput

0.479

High

540884

ZN330
Zinc finger protein 330

1

2

High-throughput

0.479

High

540833

PR20D
Proline-rich protein 20D

1

4

High-throughput

0.470

High

431492

HS90A
Heat shock protein HSP 90-alpha

1

0

Small-scale

0.458

High

540773

EPCAM
Epithelial cell adhesion molecule

1

0

Small-scale

0.458

High

540800

RS19
Small ribosomal subunit protein eS19

1

0

Small-scale

0.458

High

540817

RL37A
Large ribosomal subunit protein eL43

1

0

Small-scale

0.458

High

540819

RS14
Small ribosomal subunit protein uS11

1

0

Small-scale

0.458

High

540820

RS4X
Small ribosomal subunit protein eS4, X isoform

1

0

Small-scale

0.458

High

540821

RS24
Small ribosomal subunit protein eS24

1

0

Small-scale

0.458

High

540845

NPAT
Protein NPAT

1

0

Small-scale

0.458

High

540865

FBX25
F-box only protein 25

1

0

Small-scale

0.458

High

540868

EAF2
ELL-associated factor 2

1

0

Small-scale

0.458

High

540876

DDA1
DET1- and DDB1-associated protein 1

1

0

High-throughput

0.458

High

540881

PRR13
Proline-rich protein 13

1

0

Small-scale

0.458

High

540796

BMI1
Polycomb complex protein BMI-1

1

9

High-throughput

0.445

High

540794

CXCR5
C-X-C chemokine receptor type 5

1

2

Small-scale

0.437

High

540809

5NTC
Cytosolic purine 5'-nucleotidase

1

1

Small-scale

0.437

High

540826

TBA1B
Tubulin alpha-1B chain

1

4

Small-scale

0.437

High

540841

EF1A2
Elongation factor 1-alpha 2

1

1

Small-scale

0.437

High

540855

SCYL2
SCY1-like protein 2

1

2

Small-scale

0.437

High

540856

RL22L
Ribosomal protein eL22-like

1

1

Small-scale

0.437

High

540862

RHG24
Rho GTPase-activating protein 24

1

3

High-throughput

0.437

High

540869

PGAM5
Serine/threonine-protein phosphatase PGAM5, mitochondrial

1

1

Small-scale

0.437

High

540883

SNX24
Sorting nexin-24

2

0

High-throughput

0.316

High

540783

TGM1
Protein-glutamine gamma-glutamyltransferase K

1

0

High-throughput

0.279

Low

540782

ADRO
NADPH:adrenodoxin oxidoreductase, mitochondrial

1

0

Small-scale

0.249

Low

540822

RL31
Large ribosomal subunit protein eL31

1

0

Small-scale

0.249

Low

540828

GPC5
Glypican-5 [Cleaved into: Secreted glypican-5]

1

0

Small-scale

0.249

Low

540873

HCD2
3-hydroxyacyl-CoA dehydrogenase type-2

1

0

Small-scale

0.249

Low


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Last updated: 15 Jul 2024