Interactor 1: HPF1 (Q9NWY4)
Histone PARylation factor 1
Gene: HPF1

Interactor 2: PARP2 (Q9UGN5)
Poly [ADP-ribose] polymerase 2 (PARP-2) (hPARP-2) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 2) (ARTD2) (DNA ADP-ribosyltransferase PARP2) (EC 2.4.2.-) (NAD(+) ADP-ribosyltransferase 2) (ADPRT-2) (Poly[ADP-ribose] synthase 2) (pADPRT-2) (Protein poly-ADP-ribosyltransferase PARP2) (EC 2.4.2.-)
Gene: PARP2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.66 1.00 0.812

The method score is based on:

Property Details
Experiments 27067600, 28190768
Identification Methods pull down, affinity chromatography technology
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains DUF2228~PARP, DUF2228~PARP_reg
Common GO terms GO:0003682 - chromatin binding
GO:0005634 - nucleus
GO:0006281 - DNA repair
GO:0006302 - double-strand break repair
GO:0006974 - DNA damage response
and 3 others

more...

Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 346
Hs

1 583
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024