HitPredict

Interactor 1: RIN3 (Q8TB24)
Ras and Rab interactor 3 (Ras interaction/interference protein 3)
Gene: RIN3

Interactor 2: ES8L2 (Q9H6S3)
Epidermal growth factor receptor kinase substrate 8-like protein 2 (EPS8-like protein 2) (Epidermal growth factor receptor pathway substrate 8-related protein 2) (EPS8-related protein 2)
Gene: EPS8L2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.55	0.60	0.576

Property	Details
Experiments	25814554, unassigned1126
Identification Methods	two hybrid, two hybrid array
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0031982 - vesicle
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 985 Hs			1 715
+	Hs
		440645 RIN3_HUMAN (1-985): 0: 555: 100.00		FYN_HUMAN (431-709): 1.6e-74: 252: 14.94
+	Hs
		557395 RIN3_HUMAN (1-985): 0: 555: 100.00		SRC_HUMAN (408-709): 5.37e-73: 248: 12.66
+	Hs
		440150 RIN3_HUMAN (1-985): 0: 555: 100.00		LCK_HUMAN (416-715): 6.11e-67: 231: 13.12
+	Hs
		594053 RIN3_HUMAN (1-985): 0: 555: 100.00		NCK1_HUMAN (492-556): 3.64e-16: 83: 27.69
+	Hs
		73623 RIN3_HUMAN (1-985): 0: 555: 100.00		B2R6S4_HUMAN (492-556): 3.71e-16: 83: 27.69
+	Hs
		594023 Q6NSK7_HUMAN (1-985): 5.42e-173: 529: 89.14		NCK1_HUMAN (492-556): 3.64e-16: 83: 27.69
+	Hs
		440243 MACF1_HUMAN (595-857): 3.27e-44: 177: 15.83		LCK_HUMAN (416-715): 6.11e-67: 231: 13.12
+	Hs
		463842 MACF1_HUMAN (595-857): 3.27e-44: 177: 15.83		LYN_HUMAN (436-709): 1.77e-65: 227: 13.62
+	Hs
		176240 SYNJ2_HUMAN (181-535): 2.14e-27: 122: 16.89		FYN_HUMAN (431-709): 1.6e-74: 252: 14.94
+	Hs
		557066 MUC1_HUMAN (124-732): 1.45e-20: 100: 11.75		SRC_HUMAN (408-709): 5.37e-73: 248: 12.66
+	Hs
		319045 K0754_HUMAN (11-374): 1.28e-22: 107: 13.32		LYN_HUMAN (436-709): 1.77e-65: 227: 13.62
+	Hs
		439935 MUC1_HUMAN (124-732): 1.45e-20: 100: 11.75		LCK_HUMAN (416-715): 6.11e-67: 231: 13.12
+	Hs
		463316 MUC1_HUMAN (124-732): 1.45e-20: 100: 11.75		LYN_HUMAN (436-709): 1.77e-65: 227: 13.62
+	Hs
		215893 SYNJ1_HUMAN (23-494): 7.12e-10: 65.6: 7.69		LCK_HUMAN (416-715): 6.11e-67: 231: 13.12
+	Hs
		176246 SYNJ2_HUMAN (181-535): 2.14e-27: 122: 16.89		NCK1_HUMAN (492-556): 3.64e-16: 83: 27.69
+	Hs
		594151 MTCL1_HUMAN (229-786): 2.04e-26: 119: 13.99		NCK1_HUMAN (492-556): 3.64e-16: 83: 27.69
+	Hs
		215903 SYNJ1_HUMAN (23-494): 7.12e-10: 65.6: 7.69		NCK1_HUMAN (492-556): 3.64e-16: 83: 27.69