HitPredict

Interactor 1: ES8L1 (Q8TE68)
Epidermal growth factor receptor kinase substrate 8-like protein 1 (EPS8-like protein 1) (Epidermal growth factor receptor pathway substrate 8-related protein 1) (EPS8-related protein 1)
Gene: EPS8L1

Interactor 2: MARK1 (Q9P0L2)
Serine/threonine-protein kinase MARK1 (EC 2.7.11.1) (EC 2.7.11.26) (MAP/microtubule affinity-regulating kinase 1) (PAR1 homolog c) (Par-1c) (Par1c)
Gene: MARK1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	unassigned3799
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 723 Hs			1 795
+	Hs
		1270479 ES8L1_HUMAN (1-723): 0: 833: 100.00		MARK2_HUMAN (2-795): 0: 664: 63.51
+	Hs
		594121 NCK1_HUMAN (478-605): 5.22e-32: 130: 22.96		MARK1_HUMAN (1-795): 0: 771: 100.00
+	Hs
		440132 LCK_HUMAN (417-701): 3.52e-67: 232: 15.36		MARK2_HUMAN (2-795): 0: 664: 63.51
+	Hs
		439960 LCK_HUMAN (417-701): 3.52e-67: 232: 15.36		MARK3_HUMAN (1-795): 0: 654: 63.32
+	Hs
		463607 LYN_HUMAN (451-704): 2.55e-55: 199: 15.89		MARK2_HUMAN (2-795): 0: 664: 63.51
+	Hs
		463345 LYN_HUMAN (451-704): 2.55e-55: 199: 15.89		MARK3_HUMAN (1-795): 0: 654: 63.32
+	Hs
		593917 NCK1_HUMAN (478-605): 5.22e-32: 130: 22.96		MARK3_HUMAN (1-795): 0: 654: 63.32
+	Hs
		463709 LYN_HUMAN (451-704): 2.55e-55: 199: 15.89		MARK4_HUMAN (1-795): 0: 579: 50.93
+	Hs
		463219 YES_HUMAN (423-704): 9.98e-57: 204: 12.58		SIK2_HUMAN (45-766): 1.49e-141: 442: 28.27
+	Hs
		440528 FYN_HUMAN (430-704): 9.82e-56: 201: 13.07		AAPK1_HUMAN (34-579): 2.98e-142: 432: 27.92
+	Hs
		222200 NCK2_HUMAN (478-605): 1.6e-36: 143: 23.70		SIK2_HUMAN (45-766): 1.49e-141: 442: 28.27