Interactor 1: NDKM (O00746)
Nucleoside diphosphate kinase, mitochondrial (NDK) (NDP kinase, mitochondrial) (EC 2.7.4.6) (Nucleoside diphosphate kinase D) (NDPKD) (nm23-H4)
Gene: NME4

Interactor 2: NDK3 (Q13232)
Nucleoside diphosphate kinase 3 (NDK 3) (NDP kinase 3) (EC 2.7.4.6) (DR-nm23) (Nucleoside diphosphate kinase C) (NDPKC) (nm23-H3)
Gene: NME3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.74 1.00 0.861

The method score is based on:

Property Details
Experiments 27499296, 28514442, 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains NDK~NDK
Common GO terms GO:0004550 - nucleoside diphosphate kinase activity
GO:0005524 - ATP binding
GO:0006183 - GTP biosynthetic process
GO:0006228 - UTP biosynthetic process
GO:0006241 - CTP biosynthetic process
and 2 others

more...

Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 187
Hs

1 169
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Dm
+ Dm
+ Hs
+ Ce
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024