HitPredict

Interactor 1: MB3L1 (Q8WWY6)
Methyl-CpG-binding domain protein 3-like 1 (MBD3-like protein 1)
Gene: MBD3L1

Interactor 2: P66B (Q8WXI9)
Transcriptional repressor p66-beta (GATA zinc finger domain-containing protein 2B) (p66/p68)
Gene: GATAD2B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	1.00	0.861

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	MBD_C~P66_CC
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005634 - nucleus
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 194 Hs			1 593
+	Hs
		352208 MBD3_HUMAN (1-193): 3.42e-102: 297: 44.56		P66B_HUMAN (1-593): 0: 801: 100.00
+	Hs
		1361028 MBD2_HUMAN (1-182): 5.64e-85: 258: 41.76		P66B_HUMAN (1-593): 0: 801: 100.00
+	Hs
		1340894 MB3L2_HUMAN (26-187): 5.84e-61: 190: 45.73		P66B_HUMAN (1-593): 0: 801: 100.00
+	Hs
		352178 MBD3_HUMAN (1-193): 3.42e-102: 297: 44.56		P66A_HUMAN (4-590): 0: 551: 38.75
+	Hs
		1295273 MB3L1_HUMAN (1-194): 1.27e-98: 285: 100.00		P66A_HUMAN (4-590): 0: 551: 38.75
+	Hs
		1295318 MBD2_HUMAN (1-182): 5.64e-85: 258: 41.76		P66A_HUMAN (4-590): 0: 551: 38.75
+	Hs
		1295269 MB3L2_HUMAN (26-187): 5.84e-61: 190: 45.73		P66A_HUMAN (4-590): 0: 551: 38.75