Interactor 1: MBD3 (O95983)
Methyl-CpG-binding domain protein 3 (Methyl-CpG-binding protein MBD3)
Gene: MBD3
Interactor 2: P66B (Q8WXI9)
Transcriptional repressor p66-beta (GATA zinc finger domain-containing protein 2B) (p66/p68)
Gene: GATAD2B
Species: Homo sapiens
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.96 | 1.00 | 0.982 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 26186194, 28514442, 11756549, 24981860, 33961781, 40437099, 25416956, 21516116, 12183469, 33283408, 37071682, 16738318, 25123934 |
| Identification Methods | affinity chromatography technology, cross-linking study, two hybrid, pull down, anti tag coimmunoprecipitation, two hybrid prey pooling approach, two hybrid array, validated two hybrid |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | MBD_C~P66_CC |
| Common GO terms | GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0000785 - chromatin GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006338 - chromatin remodeling and 6 others more... |
| Homologous interactions | 7 |
Homologous interactions
Color coding for hit scores 
|
|
|||||||||||||
| + | Hs |   |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
Service provided by Combinatics, Japan
Last updated: 11Aug2025
