HitPredict

Interactor 1: Q9VC36 (Q9VC36)
Polybromo
Gene: polybromo

Interactor 2: SAYP (Q9VWF2)
Supporter of activation of yellow protein (Protein enhancer of yellow 3)
Gene: e(y)3

Species: Drosophila melanogaster

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.65	1.00	0.811

Property	Details
Experiments	19541607, 19230386
Identification Methods	affinity chromatography technology, biochemical, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	BAH~PHD, Bromodomain~PHD
Common GO terms	GO:0003682 - chromatin binding GO:0006338 - chromatin remodeling GO:0035060 - brahma complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1654 Dm			1 2006
+	Dm
		844330 TAF1_DROME (642-923): 1.45e-35: 150: 12.33		SAYP_DROME (1-2006): 0: 2447: 100.00
+	Dm
		1179552 Q9VC36_DROME (1-1654): 0: 1494: 100.00		Q7K3G5_DROME (1628-1793): 1.51e-40: 160: 30.23
+	Hs
		1199167 PB1_HUMAN (1-1394): 0: 931: 34.77		PHF10_HUMAN (1278-1805): 2.96e-98: 328: 27.17
+	Mm
		101544 F8VQD1_MOUSE (1-1394): 0: 939: 34.55		PHF10_MOUSE (1278-1805): 2.95e-95: 319: 27.54
+	Hs
		1199173 PB1_HUMAN (1-1394): 0: 931: 34.77		DPF3_HUMAN (1430-1793): 1.1e-68: 238: 17.94
+	Hs
		1199172 PB1_HUMAN (1-1394): 0: 931: 34.77		DPF1_HUMAN (1436-1795): 1.36e-65: 230: 17.78
+	Hs
		1199174 PB1_HUMAN (1-1394): 0: 931: 34.77		REQU_HUMAN (1430-1793): 1.53e-64: 227: 20.10
+	Hs
		1059704 PB1_HUMAN (1-1394): 0: 931: 34.77		CHD4_HUMAN (1470-1894): 2.3e-56: 219: 14.11
+	Hs
		1018557 PB1_HUMAN (1-1394): 0: 931: 34.77		CHD3_HUMAN (1470-1869): 7.94e-56: 217: 16.74
+	Hs
		1199218 PB1_HUMAN (1-1394): 0: 931: 34.77		TRI33_HUMAN (1426-1897): 7.34e-55: 212: 13.89
+	Hs
		782356 PB1_HUMAN (1-1394): 0: 931: 34.77		KDM5C_HUMAN (1480-1856): 1.9e-49: 196: 14.58
+	Hs
		1199175 PB1_HUMAN (1-1394): 0: 931: 34.77		KAT6A_HUMAN (1643-1793): 1.99e-36: 154: 29.22
+	Hs
		641217 DNMT1_HUMAN (306-1265): 6.19e-70: 262: 11.21		CHD4_HUMAN (1470-1894): 2.3e-56: 219: 14.11
+	Hs
		600135 TAF1_HUMAN (3-502): 2.86e-51: 202: 14.46		CHD3_HUMAN (1470-1869): 7.94e-56: 217: 16.74
+	Dm
		332801 Q8SX63_DROME (400-747): 1.92e-35: 150: 16.63		CHDM_DROME (1403-1869): 8.94e-58: 224: 14.45
+	Hs
		244728 BRD4_HUMAN (7-221): 9.54e-24: 112: 10.23		REQU_HUMAN (1430-1793): 1.53e-64: 227: 20.10
+	Hs
		244447 BRD4_HUMAN (7-221): 9.54e-24: 112: 10.23		CHD4_HUMAN (1470-1894): 2.3e-56: 219: 14.11
+	Hs
		244356 BRD4_HUMAN (7-221): 9.54e-24: 112: 10.23		CHD3_HUMAN (1470-1869): 7.94e-56: 217: 16.74
+	Hs
		244060 BRD4_HUMAN (7-221): 9.54e-24: 112: 10.23		KDM5C_HUMAN (1480-1856): 1.9e-49: 196: 14.58
+	Hs
		243764 BRD4_HUMAN (7-221): 9.54e-24: 112: 10.23		NSD2_HUMAN (1752-1831): 2.78e-13: 77.7: 21.95