Interactor 1: MTA70 (Q9VCE6)
N6-adenosine-methyltransferase MT-A70-like protein (EC 2.1.1.348) (Inducer of meiosis 4) (Methyltransferase-like 3)
Gene: Mettl3

Interactor 2: MET14 (Q9VLP7)
N6-adenosine-methyltransferase non-catalytic subunit (Karyogamy protein 4) (Methyltransferase-like protein 14) (dMettl14)
Gene: Mettl14

Species: Drosophila melanogaster

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.83 1.00 0.912

The method score is based on:

Property Details
Experiments 27919077, 28675155, 25242320, 29535189, 14605208
Identification Methods affinity chromatography technology, two hybrid
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains MT-A70~MT-A70
Common GO terms GO:0000381 - regulation of alternative mRNA splicing, via spliceosome
GO:0001510 - RNA methylation
GO:0005634 - nucleus
GO:0006397 - mRNA processing
GO:0007548 - sex differentiation
and 3 others

more...

Homologous interactions 5

Homologous interactions

Color coding for hit scores

1 608
Dm

1 397
+ Mm
+ Hs
+ Hs
+ Hs
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024