HitPredict

Interactor 1: DDB2 (Q92466)
DNA damage-binding protein 2 (DDB p48 subunit) (DDBb) (Damage-specific DNA-binding protein 2) (UV-damaged DNA-binding protein 2) (UV-DDB 2)
Gene: DDB2

Interactor 2: TCPH (Q99832)
T-complex protein 1 subunit eta (TCP-1-eta) (EC 3.6.1.-) (CCT-eta) (Chaperonin containing T-complex polypeptide 1 subunit 7) (HIV-1 Nef-interacting protein) [Cleaved into: T-complex protein 1 subunit eta, N-terminally processed]
Gene: CCT7

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.80	0.80	0.805

Property	Details
Experiments	26496610, 28514442, 33961781, unassigned3799
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Cpn60_TCP1~WD40
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 427 Hs			1 543
+	Hs
		1407576 WDR76_HUMAN (114-412): 2.62e-81: 264: 23.89		TCPH_HUMAN (1-543): 0: 647: 100.00
+	Hs
		882065 DDB2_HUMAN (1-427): 3.18e-95: 294: 100.00		TCPG_HUMAN (1-541): 0: 577: 31.09
+	Hs
		1291941 WDR5B_HUMAN (142-427): 3.12e-68: 221: 14.53		TCPH_HUMAN (1-543): 0: 647: 100.00
+	Hs
		876092 DDB2_HUMAN (1-427): 3.18e-95: 294: 100.00		TCPE_HUMAN (3-527): 0: 557: 29.59
+	Hs
		1098369 ERCC8_HUMAN (114-324): 1.49e-59: 201: 23.21		TCPH_HUMAN (1-543): 0: 647: 100.00
+	Hs
		882166 WDR76_HUMAN (114-412): 2.62e-81: 264: 23.89		TCPG_HUMAN (1-541): 0: 577: 31.09
+	Hs
		610802 DDB2_HUMAN (1-427): 3.18e-95: 294: 100.00		TCPA_HUMAN (2-533): 0: 544: 34.54
+	Hs
		876174 WDR76_HUMAN (114-412): 2.62e-81: 264: 23.89		TCPE_HUMAN (3-527): 0: 557: 29.59
+	Hs
		610894 WDR76_HUMAN (114-412): 2.62e-81: 264: 23.89		TCPA_HUMAN (2-533): 0: 544: 34.54
+	Hs
		882075 FBXW7_HUMAN (8-311): 5.97e-65: 222: 11.94		TCPG_HUMAN (1-541): 0: 577: 31.09
+	Hs
		882014 WDR5B_HUMAN (142-427): 3.12e-68: 221: 14.53		TCPG_HUMAN (1-541): 0: 577: 31.09
+	Hs
		881901 ERCC8_HUMAN (114-324): 1.49e-59: 201: 23.21		TCPG_HUMAN (1-541): 0: 577: 31.09
+	Hs
		610813 FBXW7_HUMAN (8-311): 5.97e-65: 222: 11.94		TCPA_HUMAN (2-533): 0: 544: 34.54
+	Hs
		610750 WDR5B_HUMAN (142-427): 3.12e-68: 221: 14.53		TCPA_HUMAN (2-533): 0: 544: 34.54
+	Hs
		875939 ERCC8_HUMAN (114-324): 1.49e-59: 201: 23.21		TCPE_HUMAN (3-527): 0: 557: 29.59
+	Hs
		610641 ERCC8_HUMAN (114-324): 1.49e-59: 201: 23.21		TCPA_HUMAN (2-533): 0: 544: 34.54
+	Hs
		899503 DDB2_HUMAN (1-427): 3.18e-95: 294: 100.00		TCPD_HUMAN (24-520): 4.06e-90: 288: 33.79
+	Hs
		899587 WDR76_HUMAN (114-412): 2.62e-81: 264: 23.89		TCPD_HUMAN (24-520): 4.06e-90: 288: 33.79
+	Hs
		899463 WDR5B_HUMAN (142-427): 3.12e-68: 221: 14.53		TCPD_HUMAN (24-520): 4.06e-90: 288: 33.79
+	Hs
		899369 ERCC8_HUMAN (114-324): 1.49e-59: 201: 23.21		TCPD_HUMAN (24-520): 4.06e-90: 288: 33.79