HitPredict

Interactor 1: KAPCB (P22694)
cAMP-dependent protein kinase catalytic subunit beta (PKA C-beta) (EC 2.7.11.11)
Gene: PRKACB

Interactor 2: MYH4 (Q9Y623)
Myosin-4 (Myosin heavy chain 2b) (MyHC-2b) (Myosin heavy chain 4) (Myosin heavy chain IIb) (MyHC-IIb) (Myosin heavy chain, skeletal muscle, fetal)
Gene: MYH4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	32707033
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 351 Hs			1 1939
+	Hs
		522538 KAPCB_HUMAN (1-351): 1.47e-164: 464: 100.00		MYH1_HUMAN (1-1939): 0: 1207: 94.07
+	Hs
		610795 KAPCB_HUMAN (1-351): 1.47e-164: 464: 100.00		MYH2_HUMAN (1-1939): 0: 1187: 91.50
+	Hs
		528359 KAPCB_HUMAN (1-351): 1.47e-164: 464: 100.00		MYH6_HUMAN (3-1939): 0: 1179: 80.30
+	Hs
		116964 SGK1_HUMAN (1-348): 5.91e-143: 413: 37.71		MYH1_HUMAN (1-1939): 0: 1207: 94.07
+	Mm
		554901 KPCE_MOUSE (9-351): 1.24e-139: 415: 35.85		MYH6_MOUSE (3-1931): 0: 1172: 80.82
+	Dm
		397193 KPC1_DROME (9-351): 4.59e-141: 417: 36.16		MYSN_DROME (37-1930): 0: 1017: 38.14
+	Hs
		568567 KAPCA_HUMAN (1-351): 3.72e-164: 463: 92.88		MYH9_HUMAN (985-1939): 1.02e-61: 236: 17.93
+	Hs
		681696 AKT1_HUMAN (2-347): 4.4e-147: 425: 39.03		MYH9_HUMAN (985-1939): 1.02e-61: 236: 17.93
+	Mm
		554927 KPCE_MOUSE (9-351): 1.24e-139: 415: 35.85		MYH7_MOUSE (717-1818): 9.12e-64: 243: 16.08
+	Hs
		724784 KPCE_HUMAN (3-351): 3.98e-140: 416: 34.25		MYH9_HUMAN (985-1939): 1.02e-61: 236: 17.93
+	Hs
		568568 KAPCA_HUMAN (1-351): 3.72e-164: 463: 92.88		MYH10_HUMAN (725-1631): 1.79e-43: 177: 14.97
+	Hs
		117013 SGK1_HUMAN (1-348): 5.91e-143: 413: 37.71		MYH14_HUMAN (782-1411): 5.92e-24: 113: 15.12