HitPredict

Interactor 1: TCPD (P50991)
T-complex protein 1 subunit delta (TCP-1-delta) (EC 3.6.1.-) (CCT-delta) (Chaperonin containing T-complex polypeptide 1 subunit 4) (Stimulator of TAR RNA-binding)
Gene: CCT4

Interactor 2: DDB2 (Q92466)
DNA damage-binding protein 2 (DDB p48 subunit) (DDBb) (Damage-specific DNA-binding protein 2) (UV-damaged DNA-binding protein 2) (UV-DDB 2)
Gene: DDB2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	26496610
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Cpn60_TCP1~WD40
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 539 Hs			1 427
+	Hs
		899587 TCPD_HUMAN (1-539): 0: 601: 100.00		WDR76_HUMAN (114-412): 2.62e-81: 264: 23.89
+	Hs
		899463 TCPD_HUMAN (1-539): 0: 601: 100.00		WDR5B_HUMAN (142-427): 3.12e-68: 221: 14.53
+	Hs
		899369 TCPD_HUMAN (1-539): 0: 601: 100.00		ERCC8_HUMAN (114-324): 1.49e-59: 201: 23.21
+	Hs
		899492 TCPD_HUMAN (1-539): 0: 601: 100.00		POC1B_HUMAN (14-236): 1.05e-50: 179: 12.56
+	Hs
		899326 TCPD_HUMAN (1-539): 0: 601: 100.00		WDR5_HUMAN (236-427): 6.67e-50: 173: 21.76
+	Hs
		882014 TCPG_HUMAN (12-537): 0: 552: 33.40		WDR5B_HUMAN (142-427): 3.12e-68: 221: 14.53
+	Hs
		881901 TCPG_HUMAN (12-537): 0: 552: 33.40		ERCC8_HUMAN (114-324): 1.49e-59: 201: 23.21
+	Hs
		899481 TCPD_HUMAN (1-539): 0: 601: 100.00		POC1A_HUMAN (4-184): 1.89e-34: 134: 9.29
+	Hs
		882051 TCPG_HUMAN (12-537): 0: 552: 33.40		POC1B_HUMAN (14-236): 1.05e-50: 179: 12.56
+	Hs
		899608 TCPD_HUMAN (1-539): 0: 601: 100.00		NLE1_HUMAN (279-427): 9.16e-31: 125: 16.77
+	Hs
		881861 TCPG_HUMAN (12-537): 0: 552: 33.40		WDR5_HUMAN (236-427): 6.67e-50: 173: 21.76
+	Hs
		899553 TCPD_HUMAN (1-539): 0: 601: 100.00		TBL1Y_HUMAN (277-427): 7.9e-19: 90.5: 11.88
+	Hs
		899332 TCPD_HUMAN (1-539): 0: 601: 100.00		GBB2_HUMAN (217-427): 6.3e-19: 89.3: 15.57
+	Hs
		882038 TCPG_HUMAN (12-537): 0: 552: 33.40		POC1A_HUMAN (4-184): 1.89e-34: 134: 9.29
+	Hs
		209224 TCPD_HUMAN (1-539): 0: 601: 100.00		PRP4_HUMAN (273-421): 1.55e-16: 83.6: 12.67
+	Sc
		811080 TCPD_YEAST (22-539): 0: 570: 59.20		CMR1_YEAST (98-427): 4.92e-26: 112: 17.49
+	Hs
		845257 TCPG_HUMAN (12-537): 0: 552: 33.40		LIS1_HUMAN (8-187): 2.44e-32: 128: 8.08
+	Hs
		881865 TCPG_HUMAN (12-537): 0: 552: 33.40		GBB2_HUMAN (217-427): 6.3e-19: 89.3: 15.57
+	Hs
		209218 TCPG_HUMAN (12-537): 0: 552: 33.40		PRP4_HUMAN (273-421): 1.55e-16: 83.6: 12.67
+	Sc
		792051 TCPD_YEAST (22-539): 0: 570: 59.20		GBLP_YEAST (123-315): 1.38e-10: 64: 16.34