HitPredict

Interactor 1: CLC2B (Q92478)
C-type lectin domain family 2 member B (Activation-induced C-type lectin) (C-type lectin superfamily member 2) (IFN-alpha-2b-inducing-related protein 1)
Gene: CLEC2B

Interactor 2: JAG2 (Q9Y219)
Protein jagged-2 (Jagged2) (hJ2)
Gene: JAG2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	EGF~Lectin_C
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 149 Hs			1 1238
+	Hs
		1392401 PGCB_HUMAN (8-148): 1.2e-43: 154: 18.30		JAG2_HUMAN (1-1238): 0: 671: 100.00
+	Hs
		688648 NKG2A_HUMAN (8-148): 1.03e-39: 135: 26.75		JAG2_HUMAN (1-1238): 0: 671: 100.00
+	Hs
		1177905 CL12B_HUMAN (19-146): 4.97e-35: 124: 31.66		JAG2_HUMAN (1-1238): 0: 671: 100.00
+	Hs
		1047670 CLC2B_HUMAN (1-149): 1.68e-43: 141: 100.00		NOTC2_HUMAN (315-1069): 1.96e-84: 306: 29.22
+	Hs
		446107 FCER2_HUMAN (27-146): 3.86e-38: 133: 28.46		NOTC2_HUMAN (315-1069): 1.96e-84: 306: 29.22
+	Hs
		857515 CLC2B_HUMAN (1-149): 1.68e-43: 141: 100.00		NOTC1_HUMAN (394-1069): 6.1e-73: 270: 25.56
+	Hs
		1236162 CLC4A_HUMAN (16-147): 1.35e-34: 122: 23.13		TEN4_HUMAN (384-715): 1.27e-39: 163: 22.35
+	Hs
		565088 CSPG2_HUMAN (8-146): 5.91e-44: 155: 21.85		FBN1_HUMAN (270-1102): 8.72e-25: 115: 14.72
+	Hs
		158528 NCAN_HUMAN (8-146): 1.47e-45: 160: 19.21		TENA_HUMAN (13-215): 4.21e-17: 89.6: 10.63
+	Rn
		73580 G3V8R2_RAT (8-146): 3.21e-46: 162: 20.53		B2LYI9_RAT (13-215): 2.28e-15: 83.8: 10.39
+	Hs
		1454332 CLC4A_HUMAN (16-147): 1.35e-34: 122: 23.13		TEN3_HUMAN (5-192): 2e-13: 77.7: 9.50
+	Hs
		1449505 CLC4A_HUMAN (16-147): 1.35e-34: 122: 23.13		TEN2_HUMAN (2-192): 2.59e-09: 64.2: 6.47