Protein: CLC2B
C-type lectin domain family 2 member B (Activation-induced C-type lectin) (C-type lectin superfamily member 2) (IFN-alpha-2b-inducing-related protein 1)

Gene: CLC2B, CLEC2B
Organism: Homo sapiens
Interactions: 153
UniProt ID: Q92478

Gene Ontology (top 5):
GO:0000139 - Golgi membrane
GO:0005886 - plasma membrane
GO:0030246 - carbohydrate binding
GO:0042802 - identical protein binding
GO:0048018 - receptor ligand activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1363113

CLC2B
C-type lectin domain family 2 member B

1

17

Small-scale

0.710

High

520947

HLAC
HLA class I histocompatibility antigen, C alpha chain

1

20

High-throughput

0.691

High

568076

HLAE
HLA class I histocompatibility antigen, alpha chain E

1

20

High-throughput

0.691

High

592679

ITB4
Integrin beta-4

1

16

High-throughput

0.691

High

719730

HLAF
HLA class I histocompatibility antigen, alpha chain F

1

20

High-throughput

0.691

High

857515

NOTC1
Neurogenic locus notch homolog protein 1

1

9

High-throughput

0.691

High

1022440

IDD
Integral membrane protein DGCR2/IDD

1

11

High-throughput

0.691

High

1037019

DSC2
Desmocollin-2

1

12

High-throughput

0.691

High

1047670

NOTC2
Neurogenic locus notch homolog protein 2

1

7

High-throughput

0.691

High

1105818

ADA15
Disintegrin and metalloproteinase domain-containing protein 15

1

20

High-throughput

0.691

High

1310185

AGRA3
Adhesion G protein-coupled receptor A3

1

17

High-throughput

0.691

High

1363117

SORL
Sortilin-related receptor

1

9

High-throughput

0.691

High

1363119

HMR1
Major histocompatibility complex class I-related protein 1

1

20

High-throughput

0.691

High

1363132

LRFN3
Leucine-rich repeat and fibronectin type-III domain-containing protein 3

1

20

High-throughput

0.691

High

1363135

CNTP3
Contactin-associated protein-like 3

1

14

High-throughput

0.691

High

1363145

ANTR1
Anthrax toxin receptor 1

1

4

High-throughput

0.691

High

1363162

ADA21
Disintegrin and metalloproteinase domain-containing protein 21

1

20

High-throughput

0.691

High

1363166

JAG2
Protein jagged-2

1

12

High-throughput

0.691

High

422744

A4
Amyloid-beta precursor protein

2

11

High-throughput

0.619

High

282853

CRLF1
Cytokine receptor-like factor 1

1

8

High-throughput

0.618

High

1064069

MFGM
Lactadherin

1

15

High-throughput

0.618

High

1339790

CADM4
Cell adhesion molecule 4

1

11

High-throughput

0.618

High

1363157

SE1L1
Protein sel-1 homolog 1

1

9

High-throughput

0.618

High

409464

HLAA
HLA class I histocompatibility antigen, A alpha chain

1

20

High-throughput

0.575

High

1233997

ASPH2
Aspartate beta-hydroxylase domain-containing protein 2

2

1

High-throughput

0.549

High

1287394

SYVN1
E3 ubiquitin-protein ligase synoviolin

2

7

High-throughput

0.549

High

161066

ADA10
Disintegrin and metalloproteinase domain-containing protein 10

1

20

High-throughput

0.536

High

175405

PLXB2
Plexin-B2

1

20

High-throughput

0.536

High

211934

SPIT1
Kunitz-type protease inhibitor 1

1

13

High-throughput

0.536

High

213335

ADCY6
Adenylate cyclase type 6

1

1

High-throughput

0.536

High

230829

EXTL3
Exostosin-like 3

1

5

High-throughput

0.536

High

252704

TSN3
Tetraspanin-3

1

11

High-throughput

0.536

High

270036

XYLK
Glycosaminoglycan xylosylkinase

1

2

High-throughput

0.536

High

274906

LRP5
Low-density lipoprotein receptor-related protein 5

1

2

High-throughput

0.536

High

287597

LRP6
Low-density lipoprotein receptor-related protein 6

1

2

High-throughput

0.536

High

296924

DGAT1
Diacylglycerol O-acyltransferase 1

1

2

High-throughput

0.536

High

571242

PERF
Perforin-1

1

1

High-throughput

0.536

High

612102

ITB5
Integrin beta-5

1

13

High-throughput

0.536

High

698953

CALX
Calnexin

1

20

High-throughput

0.536

High

787435

TGFR1
TGF-beta receptor type-1

1

5

High-throughput

0.536

High

844221

ECE1
Endothelin-converting enzyme 1

1

4

High-throughput

0.536

High

885493

MA2A2
Alpha-mannosidase 2x

1

4

High-throughput

0.536

High

907925

PLXA3
Plexin-A3

1

16

High-throughput

0.536

High

1008444

ADA17
Disintegrin and metalloproteinase domain-containing protein 17

1

20

High-throughput

0.536

High

1041641

TGBR3
Transforming growth factor beta receptor type 3

1

1

High-throughput

0.536

High

1049180

RON
Macrophage-stimulating protein receptor

1

20

High-throughput

0.536

High

1055336

APLP2
Amyloid beta precursor like protein 2

1

11

High-throughput

0.536

High

1083196

GALT1
Polypeptide N-acetylgalactosaminyltransferase 1

1

14

High-throughput

0.536

High

1086063

ASPH
Aspartyl/asparaginyl beta-hydroxylase

1

1

High-throughput

0.536

High

1089118

HYAL2
Hyaluronidase-2

1

2

High-throughput

0.536

High

1097854

STX5
Syntaxin-5

1

3

High-throughput

0.536

High

1105226

S39A6
Zinc transporter ZIP6

1

6

High-throughput

0.536

High

1105526

OS9
Protein OS-9

1

5

High-throughput

0.536

High

1111629

STIM1
Stromal interaction molecule 1

1

2

High-throughput

0.536

High

1124214

EI2BA
Translation initiation factor eIF2B subunit alpha

1

4

High-throughput

0.536

High

1143765

PON2
Serum paraoxonase/arylesterase 2

1

4

High-throughput

0.536

High

1159161

SGCB
Beta-sarcoglycan

1

3

High-throughput

0.536

High

1160920

PRSS8
Prostasin

1

5

High-throughput

0.536

High

1193205

OFUT4
GDP-fucose protein O-fucosyltransferase 4

1

1

High-throughput

0.536

High

1231128

SCAR3
Scavenger receptor class A member 3

1

6

High-throughput

0.536

High

1259388

TBA1A
Tubulin alpha-1A chain

1

9

High-throughput

0.536

High

1316539

MCLN2
Mucolipin-2

1

1

High-throughput

0.536

High

1325546

LARG2
Xylosyl- and glucuronyltransferase LARGE2

1

7

High-throughput

0.536

High

1335588

CHSTE
Carbohydrate sulfotransferase 14

1

5

High-throughput

0.536

High

1337885

ZNT7
Zinc transporter 7

1

7

High-throughput

0.536

High

1362069

PMGT1
Protein O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase 1

1

10

High-throughput

0.536

High

1363114

GBF1
Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1

1

6

High-throughput

0.536

High

1363115

NICA
Nicastrin

1

1

High-throughput

0.536

High

1363118

EXT2
Exostosin-2

1

5

High-throughput

0.536

High

1363123

TMX3
Protein disulfide-isomerase TMX3

1

3

High-throughput

0.536

High

1363125

DCBD2
Discoidin, CUB and LCCL domain-containing protein 2

1

19

High-throughput

0.536

High

1363127

SORT
Sortilin

1

1

High-throughput

0.536

High

1363128

TM9S2
Transmembrane 9 superfamily member 2

1

4

High-throughput

0.536

High

1363129

CSTN3
Calsyntenin-3

1

16

High-throughput

0.536

High

1363137

MCLN1
Mucolipin-1

1

1

High-throughput

0.536

High

1363141

MAGT1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit MAGT1

1

2

High-throughput

0.536

High

1363144

SEM6B
Semaphorin-6B

1

11

High-throughput

0.536

High

1363147

ITM2C
Integral membrane protein 2C

1

8

High-throughput

0.536

High

1363151

CC50A
Cell cycle control protein 50A

1

4

High-throughput

0.536

High

1363163

GBRT
Gamma-aminobutyric acid receptor subunit theta

1

3

High-throughput

0.536

High

1363167

B3GN3
N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 3

1

2

High-throughput

0.536

High

1363170

ST14
Suppressor of tumorigenicity 14 protein

1

5

High-throughput

0.536

High

1363171

BACE2
Beta-secretase 2

1

5

High-throughput

0.536

High

1363173

BIG2
Brefeldin A-inhibited guanine nucleotide-exchange protein 2

1

7

High-throughput

0.536

High

896839

DYN2
Dynamin-2

1

2

High-throughput

0.515

High

178650

DEGS1
Sphingolipid delta(4)-desaturase DES1

1

0

High-throughput

0.513

High

1332660

MIGA1
Mitoguardin 1

1

0

High-throughput

0.513

High

1363158

SUSD2
Sushi domain-containing protein 2

1

0

High-throughput

0.513

High

1363174

S4A7
Sodium bicarbonate cotransporter 3

1

0

High-throughput

0.513

High

170897

CLGN
Calmegin

1

20

High-throughput

0.489

High

321015

SUN1
SUN domain-containing protein 1

1

6

High-throughput

0.489

High

336200

TNF6B
Tumor necrosis factor receptor superfamily member 6B

1

1

High-throughput

0.489

High

337278

ATS2
A disintegrin and metalloproteinase with thrombospondin motifs 2

1

9

High-throughput

0.489

High

684502

CTNA2
Catenin alpha-2

1

2

High-throughput

0.489

High

890149

EI2BB
Translation initiation factor eIF2B subunit beta

1

4

High-throughput

0.489

High

1095914

EI2BE
Translation initiation factor eIF2B subunit epsilon

1

2

High-throughput

0.489

High

1117009

LAMB3
Laminin subunit beta-3

1

8

High-throughput

0.489

High

1125018

RCN2
Reticulocalbin-2

1

2

High-throughput

0.489

High

1147546

UBE3C
Ubiquitin-protein ligase E3C

1

2

High-throughput

0.489

High

1191919

TBB8
Tubulin beta-8 chain

1

10

High-throughput

0.489

High

1200270

FAKD1
FAST kinase domain-containing protein 1, mitochondrial

1

8

High-throughput

0.489

High

1206995

ZNG1C
Zinc-regulated GTPase metalloprotein activator 1C

1

3

High-throughput

0.489

High

1214114

DIK1A
Divergent protein kinase domain 1A

1

5

High-throughput

0.489

High

1226409

TBC9B
TBC1 domain family member 9B

1

2

High-throughput

0.489

High

1228394

SE1L3
Protein sel-1 homolog 3

1

3

High-throughput

0.489

High

1245604

TXD11
Thioredoxin domain-containing protein 11

1

3

High-throughput

0.489

High

1257976

UBP30
Ubiquitin carboxyl-terminal hydrolase 30

1

1

High-throughput

0.489

High

1315462

K2013
Uncharacterized protein KIAA2013

1

2

High-throughput

0.489

High

1323309

VPS52
Vacuolar protein sorting-associated protein 52 homolog

1

3

High-throughput

0.489

High

1327031

VMA12
Vacuolar ATPase assembly protein VMA12

1

1

High-throughput

0.489

High

1332742

PMGT2
Protein O-linked-mannose beta-1,4-N-acetylglucosaminyltransferase 2

1

1

High-throughput

0.489

High

1363120

PIGT
GPI-anchor transamidase component PIGT

1

1

High-throughput

0.489

High

1363121

PBIP1
Pre-B-cell leukemia transcription factor-interacting protein 1

1

5

High-throughput

0.489

High

1363122

ERLEC
Endoplasmic reticulum lectin 1

1

5

High-throughput

0.489

High

1363124

FACR2
Fatty acyl-CoA reductase 2

1

2

High-throughput

0.489

High

1363126

LMF1
Lipase maturation factor 1

1

1

High-throughput

0.489

High

1363131

ZNG1A
Zinc-regulated GTPase metalloprotein activator 1A

1

3

High-throughput

0.489

High

1363133

EDEM2
ER degradation-enhancing alpha-mannosidase-like protein 2

1

4

High-throughput

0.489

High

1363134

CHID1
Chitinase domain-containing protein 1

1

1

High-throughput

0.489

High

1363136

EDEM3
ER degradation-enhancing alpha-mannosidase-like protein 3

1

4

High-throughput

0.489

High

1363142

METL9
Protein-L-histidine N-pros-methyltransferase

1

1

High-throughput

0.489

High

1363143

TMX1
Thioredoxin-related transmembrane protein 1

1

7

High-throughput

0.489

High

1363146

TPC
Mitochondrial thiamine pyrophosphate carrier

1

7

High-throughput

0.489

High

1363148

EI2BG
Translation initiation factor eIF2B subunit gamma

1

2

High-throughput

0.489

High

1363152

PANK4
4'-phosphopantetheine phosphatase

1

1

High-throughput

0.489

High

1363153

MTCH1
Mitochondrial carrier homolog 1

1

9

High-throughput

0.489

High

1363154

TMEM9
Proton-transporting V-type ATPase complex assembly regulator TMEM9

1

4

High-throughput

0.489

High

1363155

EXTL2
Exostosin-like 2

1

5

High-throughput

0.489

High

1363156

FA8A1
Protein FAM8A1

1

2

High-throughput

0.489

High

1363160

SUN2
SUN domain-containing protein 2

1

6

High-throughput

0.489

High

1363161

EI2BD
Translation initiation factor eIF2B subunit delta

1

4

High-throughput

0.489

High

1363168

DJC16
DnaJ homolog subfamily C member 16

1

6

High-throughput

0.489

High

1363169

UB2J1
Ubiquitin-conjugating enzyme E2 J1

1

3

High-throughput

0.489

High

1363172

MTCH2
Mitochondrial carrier homolog 2

1

10

High-throughput

0.489

High

1363149

FBX6
F-box only protein 6

1

4

High-throughput

0.479

High

160736

TOR1A
Torsin-1A

1

3

High-throughput

0.470

High

843820

HD
Huntingtin

1

1

High-throughput

0.470

High

1363165

UBP22
Ubiquitin carboxyl-terminal hydrolase 22

2

0

High-throughput

0.313

High

173730

BTAF1
TATA-binding protein-associated factor 172

1

0

High-throughput

0.279

Low

778741

PRS7
26S proteasome regulatory subunit 7

1

0

High-throughput

0.279

Low

1151029

PCH2
Pachytene checkpoint protein 2 homolog

1

0

High-throughput

0.279

Low

1204883

MKS3
Meckelin

1

0

High-throughput

0.279

Low

1363116

GPI8
GPI-anchor transamidase

1

0

High-throughput

0.279

Low

1363130

ADPGK
ADP-dependent glucokinase

1

0

High-throughput

0.279

Low

1363138

IF5A2
Eukaryotic translation initiation factor 5A-2

1

0

High-throughput

0.279

Low

1363139

MFR1L
Mitochondrial fission regulator 1-like

1

0

High-throughput

0.279

Low

1363140

INT2
Integrator complex subunit 2

1

0

High-throughput

0.279

Low

1363150

F1142
Protein FAM114A2

1

0

High-throughput

0.279

Low

1363159

ARMX3
Armadillo repeat-containing X-linked protein 3

1

0

High-throughput

0.279

Low

1363164

PP6R1
Serine/threonine-protein phosphatase 6 regulatory subunit 1

1

0

High-throughput

0.279

Low

369716

A2MG
Alpha-2-macroglobulin

1

0

High-throughput

0.268

Low

1329692

AR6P6
ADP-ribosylation factor-like protein 6-interacting protein 6

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025