Interactor 1: HMHA1 (Q92619)
Rho GTPase-activating protein 45 [Cleaved into: Minor histocompatibility antigen HA-1 (mHag HA-1)]
Gene: ARHGAP45

Interactor 2: GMIP (Q9P107)
GEM-interacting protein (GMIP)
Gene: GMIP

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.61 1.00 0.783

The method score is based on:

Property Details
Experiments 32296183, unassigned1304
Identification Methods two hybrid, two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains GMIP-like_FCH~GMIP-like_FCH, RhoGAP~RhoGAP
Common GO terms GO:0005096 - GTPase activator activity
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0008270 - zinc ion binding
GO:0051056 - regulation of small GTPase mediated signal transduction
and 1 others

more...

Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 1136
Hs

1 970
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Last updated: 11Aug2025