HitPredict

Interactor 1: Q9VJI7 (Q9VJI7)
GEO08441p1 (Like Sm 7, isoform A) (Like Sm 7, isoform B) (Like Sm 7, isoform C) (RH73529p)
Gene: LSm7

Interactor 2: Q9VRT7 (Q9VRT7)
U6 snRNA-associated Sm-like protein LSm5
Gene: BcDNA:RE60135

Species: Drosophila melanogaster

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.60	1.00	0.775

Property	Details
Experiments	14605208, 20353594
Identification Methods	two hybrid, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	LSM~LSM
Common GO terms	GO:0000398 - mRNA splicing, via spliceosome GO:0003723 - RNA binding GO:0005688 - U6 snRNP GO:1990726 - Lsm1-7-Pat1 complex
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 110 Dm			1 91
+	Hs
		1356295 LSM7_HUMAN (13-110): 5.95e-34: 114: 76.53		LSM5_HUMAN (3-91): 1.64e-33: 112: 79.78
+	Mm
		912782 LSM7_MOUSE (13-110): 1.54e-33: 113: 75.51		LSM5_MOUSE (3-91): 1.64e-33: 112: 79.78
+	Ce
		186307 Q23543_CAEEL (10-110): 8.9e-32: 109: 56.44		O18694_CAEEL (3-91): 3.85e-34: 114: 71.91
+	Dm
		1368676 Q9VJI7_DROME (1-110): 5.99e-39: 127: 100.00		RUXE_DROME (5-91): 6.05e-26: 93.4: 24.18
+	Hs
		911766 LSM7_HUMAN (13-110): 5.95e-34: 114: 76.53		RUXE_HUMAN (7-85): 3.36e-27: 96.5: 25.30
+	Sp
		194998 LSM7_SCHPO (6-109): 2.37e-34: 116: 50.96		LSM5_SCHPO (12-90): 4.68e-26: 93.4: 51.90
+	At
		1227146 LSM7_ARATH (17-109): 1.31e-32: 111: 61.29		Q8LAK5_ARATH (4-88): 9.61e-28: 97.7: 25.84
+	At
		1352284 LSM7_ARATH (17-109): 1.31e-32: 111: 61.29		Q9ZV45_ARATH (4-88): 4.91e-27: 96.1: 25.84
+	Hs
		912210 LSM3_HUMAN (1-96): 2.86e-25: 92.7: 27.72		LSM5_HUMAN (3-91): 1.64e-33: 112: 79.78
+	Hs
		912202 LSM7_HUMAN (13-110): 5.95e-34: 114: 76.53		LSM3_HUMAN (7-86): 4.38e-23: 86.5: 24.44
+	Sc
		768241 LSM7_YEAST (2-101): 2.5e-29: 103: 43.14		LSM5_YEAST (9-88): 1.54e-23: 87.3: 38.82
+	Hs
		911607 LSM3_HUMAN (1-96): 2.86e-25: 92.7: 27.72		RUXE_HUMAN (7-85): 3.36e-27: 96.5: 25.30
+	Sc
		865977 LSM7_YEAST (2-101): 2.5e-29: 103: 43.14		LSM3_YEAST (12-91): 1.93e-22: 84.6: 21.43
+	Sc
		768230 LSM1_YEAST (3-102): 5.57e-27: 99.2: 25.23		LSM5_YEAST (9-88): 1.54e-23: 87.3: 38.82
+	Sc
		810530 LSM1_YEAST (3-102): 5.57e-27: 99.2: 25.23		LSM3_YEAST (12-91): 1.93e-22: 84.6: 21.43
+	Sp
		251599 LSM7_SCHPO (6-109): 2.37e-34: 116: 50.96		LSM7_SCHPO (4-85): 6.09e-15: 66.1: 23.26
+	At
		1228013 LSM1B_ARATH (23-106): 4.88e-26: 95.4: 28.57		LSM7_ARATH (21-91): 3.43e-16: 68.8: 21.05
+	Sc
		810527 LSM1_YEAST (3-102): 5.57e-27: 99.2: 25.23		LSM7_YEAST (21-86): 4.96e-11: 56.1: 28.38
+	Hs
		912020 LSM3_HUMAN (1-96): 2.86e-25: 92.7: 27.72		RUXG_HUMAN (19-84): 1.18e-13: 61.8: 22.73