HitPredict

Interactor 1: H2B1A (Q96A08)
Histone H2B type 1-A (Histone H2B, testis) (TSH2B.1) (hTSH2B) (Testis-specific histone H2B)
Gene: H2BC1

Interactor 2: CBX8 (Q9HC52)
Chromobox protein homolog 8 (Polycomb 3 homolog) (Pc3) (hPc3) (Rectachrome 1)
Gene: CBX8

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	21282530
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Chromo~Histone
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 127 Hs			1 389
+	Hs
		1163218 H2B2E_HUMAN (1-127): 4.41e-54: 167: 85.83		CBX8_HUMAN (1-389): 5.04e-104: 314: 100.00
+	Hs
		256992 H2B1K_HUMAN (1-127): 8.59e-54: 166: 84.25		CBX8_HUMAN (1-389): 5.04e-104: 314: 100.00
+	Hs
		754990 H2B1B_HUMAN (1-127): 6.9e-54: 166: 85.83		CBX8_HUMAN (1-389): 5.04e-104: 314: 100.00
+	Hs
		1163300 H2B2E_HUMAN (1-127): 4.41e-54: 167: 85.83		CDYL_HUMAN (2-312): 1.25e-66: 223: 14.65
+	Hs
		338847 H2B2E_HUMAN (1-127): 4.41e-54: 167: 85.83		CBX6_HUMAN (1-386): 1.09e-65: 216: 33.26
+	Hs
		338778 H2B1B_HUMAN (1-127): 6.9e-54: 166: 85.83		CBX6_HUMAN (1-386): 1.09e-65: 216: 33.26
+	Hs
		129737 H2B2E_HUMAN (1-127): 4.41e-54: 167: 85.83		CBX4_HUMAN (1-349): 3.86e-62: 210: 21.93
+	Hs
		129669 H2B1B_HUMAN (1-127): 6.9e-54: 166: 85.83		CBX4_HUMAN (1-349): 3.86e-62: 210: 21.93
+	Hs
		1163162 H2B2E_HUMAN (1-127): 4.41e-54: 167: 85.83		MPP8_HUMAN (6-356): 2.28e-52: 188: 18.85
+	Hs
		1132194 H2B2E_HUMAN (1-127): 4.41e-54: 167: 85.83		CBX2_HUMAN (2-348): 3.76e-46: 167: 22.03
+	Hs
		754846 H2B1B_HUMAN (1-127): 6.9e-54: 166: 85.83		CBX2_HUMAN (2-348): 3.76e-46: 167: 22.03
+	Hs
		216353 H2B1K_HUMAN (1-127): 8.59e-54: 166: 84.25		SUV91_HUMAN (11-102): 9.97e-27: 112: 25.25
+	Hs
		1097315 H2B2E_HUMAN (1-127): 4.41e-54: 167: 85.83		CBX3_HUMAN (9-144): 1.31e-26: 106: 25.74
+	Hs
		449715 H2B1J_HUMAN (1-127): 4.41e-54: 167: 85.04		CBX3_HUMAN (9-144): 1.31e-26: 106: 25.74
+	Hs
		256850 H2B1K_HUMAN (1-127): 8.59e-54: 166: 84.25		CBX3_HUMAN (9-144): 1.31e-26: 106: 25.74
+	Hs
		853279 H2B2E_HUMAN (1-127): 4.41e-54: 167: 85.83		CBX5_HUMAN (11-144): 1.07e-25: 104: 25.00
+	Hs
		256793 H2B1K_HUMAN (1-127): 8.59e-54: 166: 84.25		CBX5_HUMAN (11-144): 1.07e-25: 104: 25.00
+	Hs
		1014113 H2B2E_HUMAN (1-127): 4.41e-54: 167: 85.83		CBX1_HUMAN (17-122): 3.65e-23: 97.5: 28.97
+	Hs
		449707 H2B1J_HUMAN (1-127): 4.41e-54: 167: 85.04		CBX1_HUMAN (17-122): 3.65e-23: 97.5: 28.97
+	Hs
		754797 H2B1B_HUMAN (1-127): 6.9e-54: 166: 85.83		CBX1_HUMAN (17-122): 3.65e-23: 97.5: 28.97