HitPredict

Interactor 1: IMA4 (O00505)
Importin subunit alpha-4 (Importin alpha Q2) (Qip2) (Karyopherin subunit alpha-3) (SRP1-gamma)
Gene: KPNA3

Interactor 2: BRD3 (Q15059)
Bromodomain-containing protein 3 (RING3-like protein)
Gene: BRD3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.60	0.653

Property	Details
Experiments	32296183, 30554943, unassigned1304
Identification Methods	two hybrid, affinity chromatography technology, validated two hybrid, two hybrid array, two hybrid prey pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 521 Hs			1 726
+	Hs
		138601 IMA4_HUMAN (1-521): 1.86e-160: 468: 100.00		BRD4_HUMAN (3-644): 3.51e-104: 349: 52.55
+	Hs
		259660 IMA1_HUMAN (3-521): 3.15e-142: 421: 48.67		BRD4_HUMAN (3-644): 3.51e-104: 349: 52.55
+	Hs
		138784 IMA4_HUMAN (1-521): 1.86e-160: 468: 100.00		ZMYD8_HUMAN (3-713): 1.39e-58: 217: 12.28
+	At
		1373503 IMPA1_ARATH (1-521): 1.15e-155: 456: 43.26		GTE11_ARATH (1-332): 5.52e-34: 140: 15.87
+	At
		102350 IMPA2_ARATH (1-521): 2.38e-154: 453: 43.47		GTE11_ARATH (1-332): 5.52e-34: 140: 15.87
+	Hs
		910867 IMA1_HUMAN (3-521): 3.15e-142: 421: 48.67		EP300_HUMAN (4-177): 1.06e-35: 148: 23.43
+	Sc
		1039020 IMA1_YEAST (8-521): 9.84e-132: 395: 45.59		GCN5_YEAST (284-417): 7.16e-37: 145: 31.88
+	Hs
		911330 IMA5_HUMAN (5-520): 9.79e-132: 395: 45.52		KAT2A_HUMAN (267-414): 1.16e-33: 140: 28.86
+	Hs
		911364 IMA5_HUMAN (5-520): 9.79e-132: 395: 45.52		CECR2_HUMAN (130-557): 3.68e-29: 126: 14.78
+	Hs
		910970 IMA1_HUMAN (3-521): 3.15e-142: 421: 48.67		PB1_HUMAN (152-486): 2.23e-20: 99.1: 12.85
+	Hs
		639690 IMA1_HUMAN (3-521): 3.15e-142: 421: 48.67		TAF1_HUMAN (20-303): 4.78e-19: 94.5: 13.73
+	Hs
		911288 IMA5_HUMAN (5-520): 9.79e-132: 395: 45.52		PB1_HUMAN (152-486): 2.23e-20: 99.1: 12.85