HitPredict

Interactor 1: EFNA4 (O08542)
Ephrin-A4 (EPH-related receptor tyrosine kinase ligand 4) (LERK-4)
Gene: EFNA4

Interactor 2: EPHA1 (Q60750)
Ephrin type-A receptor 1 (mEpha1) (EC 2.7.10.1) (Embryonic stem cell kinase) (Tyrosine-protein kinase receptor ESK)
Gene: EPHA1

Species: Mus musculus

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	19306875
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	Ephrin~Ephrin_lbd
Common GO terms	GO:0005886 - plasma membrane GO:0007411 - axon guidance GO:0048013 - ephrin receptor signaling pathway
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 206 Mm			1 977
+	Hs
		856385 EFNA4_HUMAN (1-190): 2.44e-82: 245: 82.11		EPHA7_HUMAN (2-976): 0: 1098: 43.39
+	Hs
		665380 EFNA4_HUMAN (1-190): 2.44e-82: 245: 82.11		EPHA3_HUMAN (24-976): 0: 1083: 43.01
+	Hs
		856348 EFNA4_HUMAN (1-190): 2.44e-82: 245: 82.11		EPHA4_HUMAN (5-976): 0: 1083: 43.61
+	Hs
		856606 EFNA5_HUMAN (1-154): 5.68e-74: 224: 45.51		EPHA7_HUMAN (2-976): 0: 1098: 43.39
+	Hs
		595975 EFNA1_HUMAN (11-168): 9.4e-76: 228: 41.51		EPHA3_HUMAN (24-976): 0: 1083: 43.01
+	Hs
		595985 EFNA1_HUMAN (11-168): 9.4e-76: 228: 41.51		EPHA4_HUMAN (5-976): 0: 1083: 43.61
+	Hs
		856595 EFNA5_HUMAN (1-154): 5.68e-74: 224: 45.51		EPHA5_HUMAN (3-976): 0: 1087: 42.24
+	Hs
		665382 EFNA5_HUMAN (1-154): 5.68e-74: 224: 45.51		EPHA3_HUMAN (24-976): 0: 1083: 43.01
+	Hs
		856597 EFNA5_HUMAN (1-154): 5.68e-74: 224: 45.51		EPHA4_HUMAN (5-976): 0: 1083: 43.61
+	Hs
		595976 EFNA1_HUMAN (11-168): 9.4e-76: 228: 41.51		EPHB2_HUMAN (28-976): 0: 1077: 40.56
+	Mm
		139052 EFNA5_MOUSE (1-154): 1.22e-73: 223: 46.15		EPHB2_MOUSE (28-976): 0: 1079: 40.56
+	Hs
		856596 EFNA5_HUMAN (1-154): 5.68e-74: 224: 45.51		EPHB1_HUMAN (27-976): 0: 1078: 41.55
+	Hs
		856488 EFNA4_HUMAN (1-190): 2.44e-82: 245: 82.11		EPHA6_HUMAN (2-976): 0: 1054: 39.92
+	Hs
		665180 EFNA4_HUMAN (1-190): 2.44e-82: 245: 82.11		EPHA2_HUMAN (1-977): 0: 1036: 48.27
+	Hs
		856630 EFNA5_HUMAN (1-154): 5.68e-74: 224: 45.51		EPHA6_HUMAN (2-976): 0: 1054: 39.92
+	Hs
		595974 EFNA1_HUMAN (11-168): 9.4e-76: 228: 41.51		EPHA2_HUMAN (1-977): 0: 1036: 48.27
+	Hs
		665181 EFNA5_HUMAN (1-154): 5.68e-74: 224: 45.51		EPHA2_HUMAN (1-977): 0: 1036: 48.27
+	Hs
		665458 EFNA4_HUMAN (1-190): 2.44e-82: 245: 82.11		EPHA8_HUMAN (28-976): 0: 1011: 40.04
+	Hs
		665459 EFNA5_HUMAN (1-154): 5.68e-74: 224: 45.51		EPHA8_HUMAN (28-976): 0: 1011: 40.04
+	Hs
		595984 EFNA1_HUMAN (11-168): 9.4e-76: 228: 41.51		EPHB4_HUMAN (9-976): 0: 977: 39.47