HitPredict

Interactor 1: DCAF5 (Q96JK2)
DDB1- and CUL4-associated factor 5 (Breakpoint cluster region protein 2) (BCRP2) (WD repeat-containing protein 22)
Gene: DCAF5

Interactor 2: TCPH (Q99832)
T-complex protein 1 subunit eta (TCP-1-eta) (EC 3.6.1.-) (CCT-eta) (Chaperonin containing T-complex polypeptide 1 subunit 7) (HIV-1 Nef-interacting protein) [Cleaved into: T-complex protein 1 subunit eta, N-terminally processed]
Gene: CCT7

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.79	1.00	0.892

Property	Details
Experiments	26186194, 28514442, 33961781, unassigned3799
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Cpn60_TCP1~WD40
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 942 Hs			1 543
+	Hs
		882093 DCAF5_HUMAN (1-942): 0: 790: 98.52		TCPG_HUMAN (1-541): 0: 577: 31.09
+	Hs
		876119 DCAF5_HUMAN (1-942): 0: 790: 98.52		TCPE_HUMAN (3-527): 0: 557: 29.59
+	Hs
		610830 DCAF5_HUMAN (1-942): 0: 790: 98.52		TCPA_HUMAN (2-533): 0: 544: 34.54
+	Hs
		899529 DCAF5_HUMAN (1-942): 0: 790: 98.52		TCPD_HUMAN (24-520): 4.06e-90: 288: 33.79
+	Hs
		505657 DC8L2_HUMAN (3-388): 3.16e-86: 291: 21.13		TCPH_HUMAN (1-543): 0: 647: 100.00
+	Hs
		1215355 DCAF8_HUMAN (3-381): 6.05e-83: 281: 20.75		TCPH_HUMAN (1-543): 0: 647: 100.00
+	Hs
		881964 DCAF8_HUMAN (3-381): 6.05e-83: 281: 20.75		TCPG_HUMAN (1-541): 0: 577: 31.09
+	Hs
		876004 DCAF8_HUMAN (3-381): 6.05e-83: 281: 20.75		TCPE_HUMAN (3-527): 0: 557: 29.59
+	Hs
		505641 DC8L2_HUMAN (3-388): 3.16e-86: 291: 21.13		TCPA_HUMAN (2-533): 0: 544: 34.54
+	Hs
		610704 DCAF8_HUMAN (3-381): 6.05e-83: 281: 20.75		TCPA_HUMAN (2-533): 0: 544: 34.54
+	Hs
		1407542 KTNB1_HUMAN (221-651): 1.71e-31: 133: 10.50		TCPH_HUMAN (1-543): 0: 647: 100.00
+	Hs
		882051 POC1B_HUMAN (221-660): 8.57e-47: 176: 12.53		TCPG_HUMAN (1-541): 0: 577: 31.09
+	Hs
		876081 POC1B_HUMAN (221-660): 8.57e-47: 176: 12.53		TCPE_HUMAN (3-527): 0: 557: 29.59
+	Hs
		610789 POC1B_HUMAN (221-660): 8.57e-47: 176: 12.53		TCPA_HUMAN (2-533): 0: 544: 34.54
+	Hs
		845257 LIS1_HUMAN (266-555): 1.45e-31: 130: 11.30		TCPG_HUMAN (1-541): 0: 577: 31.09
+	Hs
		876151 KTNB1_HUMAN (221-651): 1.71e-31: 133: 10.50		TCPE_HUMAN (3-527): 0: 557: 29.59
+	Hs
		610865 KTNB1_HUMAN (221-651): 1.71e-31: 133: 10.50		TCPA_HUMAN (2-533): 0: 544: 34.54
+	Hs
		610813 FBXW7_HUMAN (261-569): 5.75e-27: 119: 13.33		TCPA_HUMAN (2-533): 0: 544: 34.54
+	Hs
		899427 DCAF8_HUMAN (3-381): 6.05e-83: 281: 20.75		TCPD_HUMAN (24-520): 4.06e-90: 288: 33.79
+	Hs
		899492 POC1B_HUMAN (221-660): 8.57e-47: 176: 12.53		TCPD_HUMAN (24-520): 4.06e-90: 288: 33.79