HitPredict

Interactor 1: TCPE (P48643)
T-complex protein 1 subunit epsilon (TCP-1-epsilon) (EC 3.6.1.-) (CCT-epsilon) (Chaperonin containing T-complex polypeptide 1 subunit 5)
Gene: CCT5

Interactor 2: DCAF5 (Q96JK2)
DDB1- and CUL4-associated factor 5 (Breakpoint cluster region protein 2) (BCRP2) (WD repeat-containing protein 22)
Gene: DCAF5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.73	0.80	0.765

Property	Details
Experiments	28514442, 33961781, unassigned3799
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Cpn60_TCP1~WD40
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 541 Hs			1 942
+	Hs
		882093 TCPG_HUMAN (14-540): 0: 574: 33.15		DCAF5_HUMAN (1-942): 0: 790: 98.52
+	Hs
		876004 TCPE_HUMAN (1-541): 0: 637: 100.00		DCAF8_HUMAN (3-381): 6.05e-83: 281: 20.75
+	Hs
		505657 TCPH_HUMAN (12-539): 0: 572: 29.64		DC8L2_HUMAN (3-388): 3.16e-86: 291: 21.13
+	Hs
		881964 TCPG_HUMAN (14-540): 0: 574: 33.15		DCAF8_HUMAN (3-381): 6.05e-83: 281: 20.75
+	Hs
		876081 TCPE_HUMAN (1-541): 0: 637: 100.00		POC1B_HUMAN (221-660): 8.57e-47: 176: 12.53
+	Hs
		876151 TCPE_HUMAN (1-541): 0: 637: 100.00		KTNB1_HUMAN (221-651): 1.71e-31: 133: 10.50
+	Hs
		882051 TCPG_HUMAN (14-540): 0: 574: 33.15		POC1B_HUMAN (221-660): 8.57e-47: 176: 12.53
+	Hs
		876070 TCPE_HUMAN (1-541): 0: 637: 100.00		POC1A_HUMAN (329-653): 5.8e-25: 110: 13.14
+	Hs
		876067 TCPE_HUMAN (1-541): 0: 637: 100.00		WDTC1_HUMAN (46-218): 5.93e-14: 78.2: 32.04
+	Hs
		875898 TCPE_HUMAN (1-541): 0: 637: 100.00		WDR5_HUMAN (1-84): 1.98e-11: 68.3: 15.12
+	Hs
		876112 TCPE_HUMAN (1-541): 0: 637: 100.00		SNR40_HUMAN (362-552): 6.53e-11: 67.2: 12.50
+	Hs
		845257 TCPG_HUMAN (14-540): 0: 574: 33.15		LIS1_HUMAN (266-555): 1.45e-31: 130: 11.30
+	Hs
		876199 TCPE_HUMAN (1-541): 0: 637: 100.00		NLE1_HUMAN (359-551): 1.03e-09: 64.1: 10.19
+	Hs
		882075 TCPG_HUMAN (14-540): 0: 574: 33.15		FBXW7_HUMAN (261-569): 5.75e-27: 119: 13.33
+	Hs
		882038 TCPG_HUMAN (14-540): 0: 574: 33.15		POC1A_HUMAN (329-653): 5.8e-25: 110: 13.14
+	Hs
		882030 TCPG_HUMAN (14-540): 0: 574: 33.15		WDTC1_HUMAN (46-218): 5.93e-14: 78.2: 32.04
+	Ce
		866358 TCPE_CAEEL (3-540): 0: 587: 68.40		LIN53_CAEEL (94-224): 3.92e-10: 65.1: 30.00
+	Hs
		882014 TCPG_HUMAN (14-540): 0: 574: 33.15		WDR5B_HUMAN (1-81): 3.36e-12: 70.6: 15.66
+	Hs
		881861 TCPG_HUMAN (14-540): 0: 574: 33.15		WDR5_HUMAN (1-84): 1.98e-11: 68.3: 15.12
+	Hs
		965190 TCPH_HUMAN (12-539): 0: 572: 29.64		WDR5_HUMAN (1-84): 1.98e-11: 68.3: 15.12