Interactor 1: BAK (O08734)
Bcl-2 homologous antagonist/killer (Apoptosis regulator BAK)
Gene: Bak1

Interactor 2: B2LA1 (Q07440)
Bcl-2-related protein A1 (A1-A) (Hemopoietic-specific early response protein) (Protein BFL-1)
Gene: Bcl2a1

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.47 1.00 0.692

The method score is based on:

Property Details
Experiments 18462686
Identification Methods x-ray crystallography, isothermal titration calorimetry
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Bcl-2~Bcl-2
Common GO terms GO:0001782 - B cell homeostasis
GO:0001783 - B cell apoptotic process
GO:0001836 - release of cytochrome c from mitochondria
GO:0005741 - mitochondrial outer membrane
GO:0008053 - mitochondrial fusion
and 7 others

more...

Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 209
Mm

1 172
+ Hs
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+ Rn
+ Mm
+ Dm
+ Hs
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+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024