HitPredict

Interactor 1: NECT4 (Q96NY8)
Nectin-4 (Ig superfamily receptor LNIR) (Nectin cell adhesion molecule 4) (Poliovirus receptor-related protein 4) [Cleaved into: Processed poliovirus receptor-related protein 4]
Gene: NECTIN4

Interactor 2: EVL (Q9UI08)
Ena/VASP-like protein (Ena/vasodilator-stimulated phosphoprotein-like)
Gene: EVL

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 510 Hs			1 416
+	Hs
		1331350 NECT4_HUMAN (1-510): 3.28e-98: 307: 100.00		ENAH_HUMAN (94-415): 6.19e-30: 123: 32.24
+	Mm
		564881 NCAM1_MOUSE (25-446): 4.01e-42: 163: 13.30		HOME1_MOUSE (1-198): 5.46e-55: 187: 19.40
+	Mm
		1229943 CNTN4_MOUSE (10-494): 8.74e-38: 150: 12.02		HOME1_MOUSE (1-198): 5.46e-55: 187: 19.40
+	Dm
		233631 O44924_DROME (20-348): 2.15e-46: 176: 19.52		ENA_DROME (2-386): 1.31e-40: 155: 24.17
+	Hs
		541641 FGFR1_HUMAN (7-476): 1.21e-56: 204: 11.31		ASPP1_HUMAN (80-367): 1.34e-26: 114: 18.62
+	Ce
		109603 SAX3_CAEEL (23-491): 1.1e-45: 173: 14.79		H2L0C7_CAEEL (14-250): 3.95e-38: 141: 22.34
+	Hs
		215899 FGFR1_HUMAN (7-476): 1.21e-56: 204: 11.31		SYNJ1_HUMAN (110-376): 1.52e-09: 62.4: 9.06