HitPredict

Interactor 1: P85B (O08908)
Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase regulatory subunit beta) (PI3K regulatory subunit beta) (PtdIns-3-kinase regulatory subunit beta) (Phosphatidylinositol 3-kinase 85 kDa regulatory subunit beta) (PI3-kinase subunit p85-beta) (PtdIns-3-kinase regulatory subunit p85-beta)
Gene: Pik3r2

Interactor 2: Q3ZB59 (Q3ZB59)
Growth factor receptor bound protein 2-associated protein 2
Gene: Gab2

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	20697350
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 722 Mm			1 665
+	Mm
		140067 P85B_MOUSE (1-722): 0: 543: 100.00		GAB2_MOUSE (1-665): 2.53e-180: 529: 99.85
+	Hs
		129351 P85B_HUMAN (1-711): 1.22e-177: 526: 88.15		GAB2_HUMAN (4-665): 1.34e-176: 520: 90.82
+	Hs
		129290 P85B_HUMAN (1-711): 1.22e-177: 526: 88.15		GAB1_HUMAN (5-664): 3.8e-125: 388: 35.71
+	Hs
		1035413 VAV3_HUMAN (611-713): 1.25e-32: 137: 33.65		GAB1_HUMAN (5-664): 3.8e-125: 388: 35.71
+	Hs
		548703 VAV_HUMAN (582-715): 3.34e-31: 132: 26.95		GAB1_HUMAN (5-664): 3.8e-125: 388: 35.71
+	Hs
		855792 VAV2_HUMAN (582-711): 1.64e-29: 127: 20.42		GAB1_HUMAN (5-664): 3.8e-125: 388: 35.71
+	Hs
		411709 LCK_HUMAN (526-721): 7.18e-30: 126: 20.57		GAB1_HUMAN (5-664): 3.8e-125: 388: 35.71
+	Hs
		986372 BTK_HUMAN (552-721): 3.84e-29: 125: 22.03		GAB1_HUMAN (5-664): 3.8e-125: 388: 35.71
+	Hs
		433345 YES_HUMAN (552-722): 8e-29: 123: 19.55		GAB1_HUMAN (5-664): 3.8e-125: 388: 35.71
+	Hs
		433750 LYN_HUMAN (497-719): 3.24e-28: 121: 17.67		GAB1_HUMAN (5-664): 3.8e-125: 388: 35.71
+	Hs
		412280 FYN_HUMAN (552-715): 3.2e-29: 124: 20.93		GAB3_HUMAN (1-656): 5.85e-93: 301: 31.55
+	Hs
		337512 ABL1_HUMAN (537-716): 2.52e-28: 123: 20.88		GAB3_HUMAN (1-656): 5.85e-93: 301: 31.55
+	Hs
		433922 LYN_HUMAN (497-719): 3.24e-28: 121: 17.67		GAB3_HUMAN (1-656): 5.85e-93: 301: 31.55
+	Hs
		203198 LCK_HUMAN (526-721): 7.18e-30: 126: 20.57		SYNJ1_HUMAN (123-640): 1.41e-53: 201: 14.86
+	Hs
		411861 LCK_HUMAN (526-721): 7.18e-30: 126: 20.57		PKHA5_HUMAN (1-402): 1.93e-49: 188: 16.26
+	Hs
		411897 LCK_HUMAN (526-721): 7.18e-30: 126: 20.57		PKHA6_HUMAN (1-536): 4.35e-44: 172: 14.39
+	Hs
		411764 LCK_HUMAN (526-721): 7.18e-30: 126: 20.57		PKHA7_HUMAN (1-549): 2.93e-39: 157: 13.71
+	Hs
		433388 YES_HUMAN (552-722): 8e-29: 123: 19.55		PKHA7_HUMAN (1-549): 2.93e-39: 157: 13.71
+	Hs
		433831 LYN_HUMAN (497-719): 3.24e-28: 121: 17.67		PKHA7_HUMAN (1-549): 2.93e-39: 157: 13.71
+	Hs
		297808 LYN_HUMAN (497-719): 3.24e-28: 121: 17.67		K0754_HUMAN (99-564): 2.73e-26: 117: 12.09