Interactor 1: SIN3A (Q96ST3)
Paired amphipathic helix protein Sin3a (Histone deacetylase complex subunit Sin3a) (Transcriptional corepressor Sin3a)
Gene: SIN3A

Interactor 2: ING1 (Q9UK53)
Inhibitor of growth protein 1
Gene: ING1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.83 1.00 0.915

The method score is based on:

Property Details
Experiments 11784859, 37071682, 11118440, 33961781, 15451426
Identification Methods affinity chromatography technology, cross-linking study, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains ING~PAH
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0005634 - nucleus
GO:0030336 - negative regulation of cell migration
GO:0030512 - negative regulation of transforming growth factor beta receptor signaling pathway
GO:0070822 - Sin3-type complex
and 2 others

more...

Homologous interactions 11

Homologous interactions

Color coding for hit scores

1 1273
Hs

1 422
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Last updated: 11Aug2025