Protein: ING1
Inhibitor of growth protein 1

Gene: ING1
Organism: Homo sapiens
Interactions: 105
UniProt ID: Q9UK53

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0005634 - nucleus
GO:0006606 - protein import into nucleus
GO:0008270 - zinc ion binding
GO:0008285 - negative regulation of cell population proliferation

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1110167

HDAC1
Histone deacetylase 1

8

16

Small-scale

0.967

High

1403046

SIN3A
Paired amphipathic helix protein Sin3a

5

11

Small-scale

0.915

High

1368194

HDAC2
Histone deacetylase 2

5

16

Small-scale

0.912

High

1208656

BRM1L
Breast cancer metastasis-suppressor 1-like protein

2

15

Small-scale

0.789

High

1439494

BRMS1
Breast cancer metastasis-suppressor 1

2

15

Small-scale

0.789

High

1159043

RBBP7
Histone-binding protein RBBP7

6

20

Small-scale

0.729

High

282326

SAP30
Histone deacetylase complex subunit SAP30

5

7

Small-scale

0.721

High

1066540

RBBP4
Histone-binding protein RBBP4

5

19

Small-scale

0.706

High

274395

SIN3B
Paired amphipathic helix protein Sin3b

1

11

High-throughput

0.691

High

1435868

SDS3
Sin3 histone deacetylase corepressor complex component SDS3

1

15

High-throughput

0.691

High

1452096

ING3
Inhibitor of growth protein 3

1

6

High-throughput

0.691

High

1445814

SHCAF
SIN3-HDAC complex-associated factor

3

3

Small-scale

0.667

High

414807

P53
Cellular tumor antigen p53

3

9

Small-scale

0.640

High

1029781

FOXK2
Forkhead box protein K2

2

12

High-throughput

0.628

High

1049891

1433F
14-3-3 protein eta

1

7

Small-scale

0.586

High

508806

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

2

6

Small-scale

0.585

High

482168

RET1
Retinol-binding protein 1

2

3

Small-scale

0.584

High

551328

PCNA
Proliferating cell nuclear antigen

2

1

Small-scale

0.584

High

958733

CSN2
COP9 signalosome complex subunit 2

1

1

Small-scale

0.561

High

1446341

DMAP1
DNA methyltransferase 1-associated protein 1

1

5

Small-scale

0.561

High

691523

1433T
14-3-3 protein theta

1

7

Small-scale

0.550

High

730338

1433B
14-3-3 protein beta/alpha

1

7

Small-scale

0.550

High

730947

1433S
14-3-3 protein sigma

1

7

Small-scale

0.550

High

966998

1433G
14-3-3 protein gamma

1

7

Small-scale

0.550

High

990847

1433Z
14-3-3 protein zeta/delta

1

7

Small-scale

0.550

High

584878

NQO1
NAD(P)H dehydrogenase [quinone] 1

1

0

Small-scale

0.537

High

711796

ARI4A
AT-rich interactive domain-containing protein 4A

1

12

High-throughput

0.536

High

855537

ATRX
Transcriptional regulator ATRX

1

18

High-throughput

0.536

High

1017509

FOXK1
Forkhead box protein K1

1

10

High-throughput

0.536

High

1123170

FHL2
Four and a half LIM domains protein 2

1

2

High-throughput

0.536

High

1155133

USF2
Upstream stimulatory factor 2

1

13

High-throughput

0.536

High

1195614

ARI4B
AT-rich interactive domain-containing protein 4B

1

15

High-throughput

0.536

High

1202259

DCAF6
DDB1- and CUL4-associated factor 6

1

9

High-throughput

0.536

High

1307266

TF2LX
Homeobox protein TGIF2LX

1

4

High-throughput

0.536

High

1416672

SALL3
Sal-like protein 3

1

9

High-throughput

0.536

High

1429918

SP130
Histone deacetylase complex subunit SAP130

1

13

High-throughput

0.536

High

1437569

SP30L
Histone deacetylase complex subunit SAP30L

1

7

High-throughput

0.536

High

1450241

MRGBP
MRG/MORF4L-binding protein

1

2

Small-scale

0.536

High

1460922

SALL2
Sal-like protein 2

1

8

High-throughput

0.536

High

972109

1433E
14-3-3 protein epsilon

1

0

Small-scale

0.527

High

1258971

H32
Histone H3.2

1

20

Small-scale

0.516

High

1439000

SMUF1
E3 ubiquitin-protein ligase SMURF1

1

5

Small-scale

0.515

High

1108817

ASAH1
Acid ceramidase

1

0

High-throughput

0.513

High

1389704

SGF29
SAGA-associated factor 29

1

0

High-throughput

0.513

High

397179

ESR1
Estrogen receptor

1

20

Small-scale

0.501

High

190176

TNC18
Trinucleotide repeat-containing gene 18 protein

1

11

High-throughput

0.489

High

920607

ARFP2
Arfaptin-2

1

2

High-throughput

0.489

High

1307214

RB6I2
ELKS/Rab6-interacting/CAST family member 1

1

9

High-throughput

0.489

High

1399120

SCLT1
Sodium channel and clathrin linker 1

1

10

High-throughput

0.489

High

1454168

CAMP3
Calmodulin-regulated spectrin-associated protein 3

1

7

High-throughput

0.489

High

1454395

BAHC1
BAH and coiled-coil domain-containing protein 1

1

9

High-throughput

0.489

High

1460924

WAC2C
WASH complex subunit 2C

1

1

High-throughput

0.489

High

143315

NFIB
Nuclear factor 1 B-type

1

20

High-throughput

0.479

High

154770

ARI1A
AT-rich interactive domain-containing protein 1A

1

8

Small-scale

0.479

High

181577

TBXT
T-box transcription factor T

1

5

High-throughput

0.479

High

355318

ACL6A
Actin-like protein 6A

1

10

Small-scale

0.479

High

386349

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

20

Small-scale

0.479

High

474359

NFIC
Nuclear factor 1 C-type

1

20

High-throughput

0.479

High

520435

ANDR
Androgen receptor

1

20

High-throughput

0.479

High

685383

PAX6
Paired box protein Pax-6

1

4

High-throughput

0.479

High

775929

HNF1B
Hepatocyte nuclear factor 1-beta

1

10

High-throughput

0.479

High

776264

SOX6
Transcription factor SOX-6

1

20

High-throughput

0.479

High

834085

HNF4A
Hepatocyte nuclear factor 4-alpha

1

20

High-throughput

0.479

High

842885

CDN2A
Cyclin-dependent kinase inhibitor 2A

1

6

Small-scale

0.479

High

872866

SOX2
Transcription factor SOX-2

1

20

High-throughput

0.479

High

903513

SMCA4
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4

1

19

Small-scale

0.479

High

911151

IMA1
Importin subunit alpha-1

1

13

Small-scale

0.479

High

944759

KLF3
Krueppel-like factor 3

1

20

High-throughput

0.479

High

980515

H4
Histone H4

1

11

High-throughput

0.479

High

1067816

EP300
Histone acetyltransferase p300

1

20

Small-scale

0.479

High

1086721

SNF5
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1

1

2

Small-scale

0.479

High

1088087

NFIA
Nuclear factor 1 A-type

1

20

High-throughput

0.479

High

1115132

CUL4A
Cullin-4A

1

5

Small-scale

0.479

High

1118693

KLF9
Krueppel-like factor 9

1

20

High-throughput

0.479

High

1134422

IMB1
Importin subunit beta-1

1

4

Small-scale

0.479

High

1152757

ELF2
ETS-related transcription factor Elf-2

1

12

High-throughput

0.479

High

1155886

EZH2
Histone-lysine N-methyltransferase EZH2

1

20

High-throughput

0.479

High

1161431

HIF1A
Hypoxia-inducible factor 1-alpha

1

4

Small-scale

0.479

High

1311741

CCAR1
Cell division cycle and apoptosis regulator protein 1

1

8

High-throughput

0.479

High

1312390

SIR2
NAD-dependent protein deacetylase sirtuin-2

1

8

Small-scale

0.479

High

1313513

SMC5
Structural maintenance of chromosomes protein 5

1

7

High-throughput

0.479

High

1347571

SMRC2
SWI/SNF complex subunit SMARCC2

1

16

Small-scale

0.479

High

1351191

SP7
Transcription factor Sp7

1

17

High-throughput

0.479

High

1357171

GATD1
GATA zinc finger domain-containing protein 1

1

3

High-throughput

0.479

High

1368522

CBP
CREB-binding protein

1

20

Small-scale

0.479

High

1369220

KAT2B
Histone acetyltransferase KAT2B

1

17

Small-scale

0.479

High

1370727

SMRC1
SWI/SNF complex subunit SMARCC1

1

11

Small-scale

0.479

High

1371765

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

1

3

Small-scale

0.479

High

1388766

SIR1
NAD-dependent protein deacetylase sirtuin-1

1

8

Small-scale

0.479

High

1392082

SMRD1
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1

1

1

Small-scale

0.479

High

1401436

CIC
Protein capicua homolog

1

20

High-throughput

0.479

High

1416944

KLF16
Krueppel-like factor 16

1

17

High-throughput

0.479

High

1437233

NANOG
Homeobox protein NANOG

1

11

High-throughput

0.479

High

1459247

ZRAN1
Ubiquitin thioesterase ZRANB1

1

4

High-throughput

0.479

High

1460379

KLF15
Krueppel-like factor 15

1

20

High-throughput

0.479

High

1460923

TRRAP
Transformation/transcription domain-associated protein

1

12

Small-scale

0.479

High

1460925

KLF12
Krueppel-like factor 12

1

20

High-throughput

0.479

High

1136110

PAF15
PCNA-associated factor

1

0

Small-scale

0.458

High

1252860

ZN704
Zinc finger protein 704

1

1

High-throughput

0.445

High

822205

CTRL
Chymotrypsin-like protease CTRL-1

1

2

Small-scale

0.437

High

995884

ACTC
Actin, alpha cardiac muscle 1

1

6

High-throughput

0.437

High

1225392

WAC2A
WASH complex subunit 2A

1

1

High-throughput

0.407

High

1382603

EXOC4
Exocyst complex component 4

2

0

High-throughput

0.316

High

329995

ZWINT
Outer kinetochore KNL1 complex subunit ZWINT

1

0

High-throughput

0.279

Low

1458727

DKK2
Dickkopf-related protein 2

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025