Interactor 1: MP2K3 (O09110)
Dual specificity mitogen-activated protein kinase kinase 3 (MAP kinase kinase 3) (MAPKK 3) (EC 2.7.12.2) (MAPK/ERK kinase 3) (MEK 3)
Gene: Map2k3

Interactor 2: TGFR2 (Q62312)
TGF-beta receptor type-2 (TGFR-2) (EC 2.7.11.30) (TGF-beta type II receptor) (Transforming growth factor-beta receptor type II) (TGF-beta receptor type II) (TbetaR-II)
Gene: Tgfbr2

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 24319055
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains PK_Tyr_Ser-Thr~Pkinase
Common GO terms GO:0005524 - ATP binding
GO:0007507 - heart development
GO:0016310 - phosphorylation
Homologous interactions 6

Homologous interactions

Color coding for hit scores

1 347
Mm

1 567
+ Zm
+ Hs
+ Hs
+ Hs
+ Hs
+ Zm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024