HitPredict

Interactor 1: PSB7 (Q99436)
Proteasome subunit beta type-7 (EC 3.4.25.1) (Macropain chain Z) (Multicatalytic endopeptidase complex chain Z) (Proteasome subunit Z) (Proteasome subunit beta-2) (beta-2)
Gene: PSMB7

Interactor 2: POMP (Q9Y244)
Proteasome maturation protein (Proteassemblin) (Protein UMP1 homolog) (hUMP1) (Voltage-gated K channel beta subunit 4.1)
Gene: POMP

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.93	1.00	0.967

Property	Details
Experiments	26186194, 28514442, 33961781, 35271311, 14733938, 17948026, unassigned3799
Identification Methods	affinity chromatography technology, two hybrid, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	Proteasome~UMP1
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 277 Hs			1 141
+	Hs
		1233731 Q6IBT1_HUMAN (1-277): 4.15e-104: 305: 99.64		POMP_HUMAN (1-141): 3.91e-75: 221: 100.00
+	Hs
		822173 PSB10_HUMAN (7-276): 1.59e-91: 273: 56.67		POMP_HUMAN (1-141): 3.91e-75: 221: 100.00
+	Hs
		700762 PSA5_HUMAN (13-241): 1.34e-82: 249: 18.52		POMP_HUMAN (1-141): 3.91e-75: 221: 100.00
+	Hs
		700487 PSB8_HUMAN (31-243): 1.72e-78: 240: 24.30		POMP_HUMAN (1-141): 3.91e-75: 221: 100.00
+	Hs
		681081 PSA1_HUMAN (16-261): 4.62e-76: 233: 17.44		POMP_HUMAN (1-141): 3.91e-75: 221: 100.00
+	Hs
		701095 PSB6_HUMAN (41-229): 5.14e-76: 232: 31.58		POMP_HUMAN (1-141): 3.91e-75: 221: 100.00
+	Hs
		701247 PSB5_HUMAN (42-243): 1.59e-74: 230: 26.11		POMP_HUMAN (1-141): 3.91e-75: 221: 100.00
+	Dm
		1477613 Q9W470_DROME (4-275): 1.27e-88: 267: 55.15		Q9VIJ5_DROME (40-140): 1.88e-46: 148: 50.50
+	Dm
		1477607 Q9VUJ1_DROME (10-277): 7.79e-84: 253: 64.82		Q9VIJ5_DROME (40-140): 1.88e-46: 148: 50.50
+	Dm
		1376930 PSA5_DROME (13-242): 4.84e-81: 245: 17.48		Q9VIJ5_DROME (40-140): 1.88e-46: 148: 50.50
+	Dm
		1264714 Q7K148_DROME (5-251): 4.62e-77: 237: 26.91		Q9VIJ5_DROME (40-140): 1.88e-46: 148: 50.50
+	Dm
		1346350 Q8T915_DROME (12-262): 1.24e-74: 232: 39.53		Q9VIJ5_DROME (40-140): 1.88e-46: 148: 50.50
+	Dm
		47796 A0AQH0_DROME (41-247): 5.44e-72: 222: 26.92		Q9VIJ5_DROME (40-140): 1.88e-46: 148: 50.50
+	Hs
		700549 PSB9_HUMAN (42-227): 9.75e-21: 89.7: 29.41		POMP_HUMAN (1-141): 3.91e-75: 221: 100.00