HitPredict

Interactor 1: FYCO1 (Q9BQS8)
FYVE and coiled-coil domain-containing protein 1 (Zinc finger FYVE domain-containing protein 7)
Gene: FYCO1

Interactor 2: MLP3C (Q9BXW4)
Microtubule-associated protein 1 light chain 3 gamma (Autophagy-related protein LC3 C) (Autophagy-related ubiquitin-like modifier LC3 C) (MAP1 light chain 3-like protein 3) (Microtubule-associated proteins 1A/1B light chain 3C) (MAP1A/MAP1B LC3 C) (MAP1A/MAP1B light chain 3 C)
Gene: MAP1LC3C

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.67	0.60	0.636

Property	Details
Experiments	31857374, 20562859
Identification Methods	pull down, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005776 - autophagosome
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 1478 Hs			1 147
+	Hs
		328134 FYCO1_HUMAN (1-1478): 1.9e-144: 482: 100.00		GBRAP_HUMAN (13-127): 3.46e-54: 168: 38.26
+	Hs
		952320 FYCO1_HUMAN (1-1478): 1.9e-144: 482: 100.00		GBRL2_HUMAN (13-126): 1.66e-54: 168: 42.98
+	Hs
		1410941 FYCO1_HUMAN (1-1478): 1.9e-144: 482: 100.00		MLP3A_HUMAN (7-126): 2.5e-53: 165: 59.17
+	Hs
		1410937 FYCO1_HUMAN (1-1478): 1.9e-144: 482: 100.00		MLP3B_HUMAN (7-127): 8.19e-53: 164: 54.55
+	Hs
		1410939 FYCO1_HUMAN (1-1478): 1.9e-144: 482: 100.00		GBRL1_HUMAN (13-126): 4.78e-52: 162: 39.47
+	Hs
		773013 MYH9_HUMAN (574-1367): 8.52e-33: 141: 12.76		GBRL1_HUMAN (13-126): 4.78e-52: 162: 39.47
+	Hs
		1253036 RUFY4_HUMAN (1032-1228): 1.99e-09: 64.2: 21.32		MLP3C_HUMAN (1-147): 4.66e-72: 214: 100.00
+	Hs
		327782 DESP_HUMAN (232-1121): 6.85e-14: 79.7: 22.05		GBRAP_HUMAN (13-127): 3.46e-54: 168: 38.26
+	Hs
		587605 DESP_HUMAN (232-1121): 6.85e-14: 79.7: 22.05		GBRL2_HUMAN (13-126): 1.66e-54: 168: 42.98
+	Hs
		587803 DESP_HUMAN (232-1121): 6.85e-14: 79.7: 22.05		MLP3A_HUMAN (7-126): 2.5e-53: 165: 59.17
+	Hs
		587797 DESP_HUMAN (232-1121): 6.85e-14: 79.7: 22.05		MLP3B_HUMAN (7-127): 8.19e-53: 164: 54.55
+	Hs
		587800 DESP_HUMAN (232-1121): 6.85e-14: 79.7: 22.05		GBRL1_HUMAN (13-126): 4.78e-52: 162: 39.47
+	Hs
		1143256 PLEC_HUMAN (385-1169): 2.59e-09: 64.7: 22.38		MLP3B_HUMAN (7-127): 8.19e-53: 164: 54.55
+	Hs
		1143259 PLEC_HUMAN (385-1169): 2.59e-09: 64.7: 22.38		GBRL1_HUMAN (13-126): 4.78e-52: 162: 39.47