Protein: RUFY4
RUN and FYVE domain-containing protein 4

Gene: RUFY4
Organism: Homo sapiens
Interactions: 22
UniProt ID: Q6ZNE9

Gene Ontology (top 5):
GO:0000045 - autophagosome assembly
GO:0005776 - autophagosome
GO:0008270 - zinc ion binding
GO:0016239 - positive regulation of macroautophagy
GO:0032266 - phosphatidylinositol-3-phosphate binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1253033

LNX1
E3 ubiquitin-protein ligase LNX

3

5

High-throughput

0.675

High

163981

NDC80
Kinetochore protein NDC80 homolog

5

15

High-throughput

0.663

High

1253036

MLP3C
Microtubule-associated protein 1 light chain 3 gamma

2

20

High-throughput

0.606

High

937480

CDN2D
Cyclin-dependent kinase 4 inhibitor D

2

5

High-throughput

0.553

High

843691

HD
Huntingtin

1

2

High-throughput

0.515

High

221738

TPPC3
Trafficking protein particle complex subunit 3

1

1

High-throughput

0.489

High

839781

EPS15
Epidermal growth factor receptor substrate 15

1

16

High-throughput

0.489

High

1253030

TPC6B
Trafficking protein particle complex subunit 6B

1

1

High-throughput

0.489

High

1253032

TPPC5
Trafficking protein particle complex subunit 5

1

1

High-throughput

0.489

High

1253037

TPC2L
Trafficking protein particle complex subunit 2-like protein

1

1

High-throughput

0.489

High

1253038

TPPC4
Trafficking protein particle complex subunit 4

1

1

High-throughput

0.489

High

1253039

TPPC1
Trafficking protein particle complex subunit 1

1

1

High-throughput

0.489

High

109430

G5E9A7
DM1 locus, WD repeat containing

1

11

High-throughput

0.470

High

385878

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

20

High-throughput

0.470

High

570467

GFAP
Glial fibrillary acidic protein

1

20

High-throughput

0.470

High

767243

MERL
Merlin

1

4

High-throughput

0.470

High

1253029

SPRE1
Sprouty-related, EVH1 domain-containing protein 1

1

1

High-throughput

0.470

High

1253031

Q86WV8
TSC complex subunit 1

1

1

High-throughput

0.470

High

515702

TPC2B
Trafficking protein particle complex subunit 2B

1

1

High-throughput

0.437

High

1253035

TPPC9
Trafficking protein particle complex subunit 9

3

0

High-throughput

0.345

High

874041

TPC10
Trafficking protein particle complex subunit 10

1

0

High-throughput

0.279

Low

1253034

TPC14
Trafficking protein particle complex subunit 14

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025