HitPredict

Interactor 1: WDR83 (Q9BRX9)
WD repeat domain-containing protein 83 (Mitogen-activated protein kinase organizer 1) (MAPK organizer 1)
Gene: WDR83

Interactor 2: AMRA1 (Q9C0C7)
Activating molecule in BECN1-regulated autophagy protein 1 (DDB1- and CUL4-associated factor 3)
Gene: AMBRA1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.80	0.514

Property	Details
Experiments	unassigned3799
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	WD40~WD40
Common GO terms	-
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 315 Hs			1 1298
+	Hs
		222461 PLRG1_HUMAN (2-312): 6.04e-86: 268: 23.15		WDR5_HUMAN (3-297): 1.09e-86: 287: 18.39
+	Hs
		845264 LIS1_HUMAN (63-312): 7.66e-76: 239: 17.71		WDR5_HUMAN (3-297): 1.09e-86: 287: 18.39
+	Hs
		965141 FBXW7_HUMAN (2-258): 1.36e-67: 225: 23.02		WDR5_HUMAN (3-297): 1.09e-86: 287: 18.39
+	Hs
		1387527 WDR83_HUMAN (1-315): 9.92e-102: 302: 100.00		SNR40_HUMAN (45-334): 1.8e-54: 196: 12.04
+	Hs
		251027 PRP17_HUMAN (8-304): 8.85e-88: 275: 23.40		SNR40_HUMAN (45-334): 1.8e-54: 196: 12.04
+	Hs
		222515 PLRG1_HUMAN (2-312): 6.04e-86: 268: 23.15		SNR40_HUMAN (45-334): 1.8e-54: 196: 12.04
+	Hs
		964797 WDR5_HUMAN (140-312): 2.14e-52: 176: 23.60		WDR5_HUMAN (3-297): 1.09e-86: 287: 18.39
+	Hs
		845250 LIS1_HUMAN (63-312): 7.66e-76: 239: 17.71		LIS1_HUMAN (123-363): 2.02e-35: 142: 12.30
+	Mm
		988931 LIS1_MOUSE (63-312): 6.04e-76: 239: 17.71		LIS1_MOUSE (123-363): 1.82e-35: 142: 12.30
+	Dm
		1463921 Q9VYQ9_DROME (2-313): 9.36e-88: 272: 21.78		WDS_DROME (174-342): 1.41e-22: 102: 10.53
+	Hs
		965071 WDR5_HUMAN (140-312): 2.14e-52: 176: 23.60		WDR5B_HUMAN (4-207): 3.21e-55: 197: 14.68
+	Hs
		965151 WDR5_HUMAN (140-312): 2.14e-52: 176: 23.60		SNR40_HUMAN (45-334): 1.8e-54: 196: 12.04
+	Dm
		1463899 WDS_DROME (2-266): 7.93e-81: 251: 22.26		WDS_DROME (174-342): 1.41e-22: 102: 10.53
+	Ca
		515422 TUP1_CANAL (100-314): 5.79e-54: 185: 15.48		TUP1_CANAL (6-168): 1.57e-35: 144: 16.85
+	Hs
		845346 LIS1_HUMAN (63-312): 7.66e-76: 239: 17.71		KTNB1_HUMAN (167-610): 4.74e-17: 88.7: 8.64
+	Hs
		1380064 FBXW7_HUMAN (2-258): 1.36e-67: 225: 23.02		FBXW7_HUMAN (164-314): 4.21e-18: 92.2: 10.53
+	Dm
		1463923 FBXW7_DROME (2-258): 1.52e-61: 213: 21.81		WDS_DROME (174-342): 1.41e-22: 102: 10.53