HitPredict

Interactor 1: RAB7A (P51149)
Ras-related protein Rab-7a (EC 3.6.5.2)
Gene: RAB7A

Interactor 2: KDIS (Q9ULH0)
Kinase D-interacting substrate of 220 kDa (Ankyrin repeat-rich membrane-spanning protein)
Gene: KIDINS220

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	1.00	0.789

Property	Details
Experiments	26496610, 34432599
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Ank~Ras, Ank_2~Ras, Ank_4~Ras
Common GO terms	GO:0005770 - late endosome GO:0005829 - cytosol
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 207 Hs			1 1771
+	Hs
		914450 RB11A_HUMAN (2-205): 1.09e-78: 236: 30.99		KDIS_HUMAN (13-1771): 0: 2634: 100.00
+	Hs
		845801 RAB9A_HUMAN (5-177): 3.51e-68: 209: 56.65		KDIS_HUMAN (13-1771): 0: 2634: 100.00
+	Hs
		844793 RAB5C_HUMAN (9-179): 1.56e-37: 131: 42.44		KDIS_HUMAN (13-1771): 0: 2634: 100.00
+	Hs
		845347 RAB7A_HUMAN (1-207): 5.09e-80: 239: 100.00		ANR50_HUMAN (1-307): 2.84e-80: 295: 31.27
+	Hs
		862018 RB11A_HUMAN (2-205): 1.09e-78: 236: 30.99		DAPK1_HUMAN (4-305): 4.92e-35: 149: 31.58
+	Hs
		257589 RAB5C_HUMAN (9-179): 1.56e-37: 131: 42.44		ANR17_HUMAN (261-522): 2.37e-53: 209: 19.32
+	Mm
		71299 RAB13_MOUSE (1-202): 1.26e-79: 238: 33.50		ANR44_MOUSE (1-103): 1.84e-18: 94.4: 19.63
+	Mm
		71295 RAB9B_MOUSE (3-205): 1.51e-70: 214: 53.20		ANR44_MOUSE (1-103): 1.84e-18: 94.4: 19.63