HitPredict

Interactor 1: TBB2B (Q9BVA1)
Tubulin beta-2B chain
Gene: TUBB2B

Interactor 2: RIPK3 (Q9Y572)
Receptor-interacting serine/threonine-protein kinase 3 (EC 2.7.11.1) (RIP-like protein kinase 3) (Receptor-interacting protein 3) (RIP-3)
Gene: RIPK3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	14743216
Identification Methods	tandem affinity purification
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 445 Hs			1 518
+	Hs
		457800 TBB5_HUMAN (1-429): 0: 717: 97.44		RIPK3_HUMAN (1-518): 5.7e-157: 458: 100.00
+	Hs
		1108707 TBB3_HUMAN (1-445): 0: 719: 92.15		Q9H4D1_HUMAN (20-286): 3.63e-38: 150: 35.74
+	Hs
		457697 TBB5_HUMAN (1-429): 0: 717: 97.44		Q9H4D1_HUMAN (20-286): 3.63e-38: 150: 35.74
+	Hs
		1415113 TBB2B_HUMAN (1-430): 0: 716: 100.00		Q9H4D1_HUMAN (20-286): 3.63e-38: 150: 35.74
+	Hs
		943937 TBB3_HUMAN (1-445): 0: 719: 92.15		RIPK4_HUMAN (20-374): 1.36e-36: 146: 30.39
+	Hs
		997512 TBB4B_HUMAN (1-427): 0: 715: 98.13		Q9H4D1_HUMAN (20-286): 3.63e-38: 150: 35.74
+	Hs
		1414191 TBB6_HUMAN (1-432): 0: 713: 92.36		Q9H4D1_HUMAN (20-286): 3.63e-38: 150: 35.74
+	Hs
		457336 TBB5_HUMAN (1-429): 0: 717: 97.44		RIPK4_HUMAN (20-374): 1.36e-36: 146: 30.39
+	Hs
		1118594 TBB2A_HUMAN (1-430): 0: 712: 99.54		Q9H4D1_HUMAN (20-286): 3.63e-38: 150: 35.74
+	Hs
		944061 TBB2B_HUMAN (1-430): 0: 716: 100.00		RIPK4_HUMAN (20-374): 1.36e-36: 146: 30.39
+	Hs
		408164 TBB4A_HUMAN (1-427): 0: 711: 96.72		Q9H4D1_HUMAN (20-286): 3.63e-38: 150: 35.74
+	Hs
		943905 TBB4B_HUMAN (1-427): 0: 715: 98.13		RIPK4_HUMAN (20-374): 1.36e-36: 146: 30.39
+	Hs
		944059 TBB6_HUMAN (1-432): 0: 713: 92.36		RIPK4_HUMAN (20-374): 1.36e-36: 146: 30.39
+	Hs
		943939 TBB2A_HUMAN (1-430): 0: 712: 99.54		RIPK4_HUMAN (20-374): 1.36e-36: 146: 30.39
+	Hs
		408013 TBB4A_HUMAN (1-427): 0: 711: 96.72		RIPK4_HUMAN (20-374): 1.36e-36: 146: 30.39
+	Hs
		457416 TBB5_HUMAN (1-429): 0: 717: 97.44		RIPK1_HUMAN (21-288): 1.19e-33: 137: 33.90
+	Hs
		214373 TBB5_HUMAN (1-429): 0: 717: 97.44		RIPK2_HUMAN (14-291): 6.45e-33: 133: 32.32
+	Hs
		214458 TBB2B_HUMAN (1-430): 0: 716: 100.00		RIPK2_HUMAN (14-291): 6.45e-33: 133: 32.32
+	Hs
		408052 TBB4A_HUMAN (1-427): 0: 711: 96.72		RIPK1_HUMAN (21-288): 1.19e-33: 137: 33.90
+	Hs
		214369 TBB4A_HUMAN (1-427): 0: 711: 96.72		RIPK2_HUMAN (14-291): 6.45e-33: 133: 32.32