HitPredict

Interactor 1: TRI38 (O00635)
E3 ubiquitin-protein ligase TRIM38 (EC 2.3.2.27) (RING finger protein 15) (Tripartite motif-containing protein 38) (Zinc finger protein RoRet)
Gene: TRIM38

Interactor 2: UB2D2 (P62837)
Ubiquitin-conjugating enzyme E2 D2 (EC 2.3.2.23) ((E3-independent) E2 ubiquitin-conjugating enzyme D2) (EC 2.3.2.24) (E2 ubiquitin-conjugating enzyme D2) (Ubiquitin carrier protein D2) (Ubiquitin-conjugating enzyme E2(17)KB 2) (Ubiquitin-conjugating enzyme E2-17 kDa 2) (Ubiquitin-protein ligase D2) (p53-regulated ubiquitin-conjugating enzyme 1)
Gene: UBE2D2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.481

Property	Details
Experiments	21143188
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0061630 - ubiquitin protein ligase activity GO:0070936 - protein K48-linked ubiquitination
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 465 Hs			1 147
+	Hs
		623204 RO52_HUMAN (1-462): 3.6e-152: 443: 40.76		UB2D1_HUMAN (1-147): 1.1e-82: 241: 89.12
+	Hs
		623249 RO52_HUMAN (1-462): 3.6e-152: 443: 40.76		UB2D2_HUMAN (1-147): 1.58e-82: 240: 100.00
+	Hs
		623219 RO52_HUMAN (1-462): 3.6e-152: 443: 40.76		UB2D3_HUMAN (1-147): 2.22e-81: 237: 97.28
+	Hs
		142704 TRI38_HUMAN (1-465): 7.31e-148: 431: 100.00		UB2D4_HUMAN (1-147): 3.4e-83: 242: 93.20
+	Hs
		1439327 TRI39_HUMAN (7-465): 3.36e-147: 431: 37.10		UB2D4_HUMAN (1-147): 3.4e-83: 242: 93.20
+	Hs
		142669 TRI38_HUMAN (1-465): 7.31e-148: 431: 100.00		UB2D1_HUMAN (1-147): 1.1e-82: 241: 89.12
+	Hs
		906790 TRI39_HUMAN (7-465): 3.36e-147: 431: 37.10		UB2D1_HUMAN (1-147): 1.1e-82: 241: 89.12
+	Hs
		982330 TRI39_HUMAN (7-465): 3.36e-147: 431: 37.10		UB2D2_HUMAN (1-147): 1.58e-82: 240: 100.00
+	Hs
		142674 TRI38_HUMAN (1-465): 7.31e-148: 431: 100.00		UB2D3_HUMAN (1-147): 2.22e-81: 237: 97.28
+	Hs
		957208 TRI39_HUMAN (7-465): 3.36e-147: 431: 37.10		UB2D3_HUMAN (1-147): 2.22e-81: 237: 97.28
+	Hs
		957138 TRI58_HUMAN (1-464): 5.6e-146: 427: 39.23		UB2D3_HUMAN (1-147): 2.22e-81: 237: 97.28
+	Hs
		623207 RO52_HUMAN (1-462): 3.6e-152: 443: 40.76		UB2E1_HUMAN (4-146): 1.76e-72: 216: 65.73
+	Hs
		1397295 TRI39_HUMAN (7-465): 3.36e-147: 431: 37.10		UB2E2_HUMAN (4-146): 1.32e-74: 222: 65.73
+	Hs
		142698 TRI38_HUMAN (1-465): 7.31e-148: 431: 100.00		UB2E2_HUMAN (4-146): 1.32e-74: 222: 65.73
+	Hs
		1381205 TRI39_HUMAN (7-465): 3.36e-147: 431: 37.10		UB2E3_HUMAN (4-146): 5.71e-74: 221: 66.43
+	Hs
		142694 TRI38_HUMAN (1-465): 7.31e-148: 431: 100.00		UB2E3_HUMAN (4-146): 5.71e-74: 221: 66.43
+	Hs
		623221 RO52_HUMAN (1-462): 3.6e-152: 443: 40.76		UBE2N_HUMAN (4-147): 1.73e-68: 205: 47.22
+	Hs
		142670 TRI38_HUMAN (1-465): 7.31e-148: 431: 100.00		UB2E1_HUMAN (4-146): 1.76e-72: 216: 65.73
+	Hs
		909393 TRI39_HUMAN (7-465): 3.36e-147: 431: 37.10		UB2E1_HUMAN (4-146): 1.76e-72: 216: 65.73
+	Hs
		957847 TRI39_HUMAN (7-465): 3.36e-147: 431: 37.10		UBE2N_HUMAN (4-147): 1.73e-68: 205: 47.22