HitPredict

Interactor 1: KLK15 (Q9H2R5)
Kallikrein-15 (EC 3.4.21.-) (ACO protease)
Gene: KLK15

Interactor 2: TMED5 (Q9Y3A6)
Transmembrane emp24 domain-containing protein 5 (p24 family protein gamma-2) (p24gamma2) (p28)
Gene: TMED5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.50	0.489

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 256 Hs			1 229
+	Hs
		437840 HEPS_HUMAN (4-254): 2.77e-96: 290: 30.55		TMED5_HUMAN (1-229): 9.22e-79: 237: 100.00
+	Hs
		944936 TMPS3_HUMAN (4-256): 2.48e-99: 298: 30.45		TMED7_HUMAN (28-229): 5.2e-70: 215: 31.03
+	Hs
		1105884 KLK5_HUMAN (5-256): 9.44e-97: 286: 40.55		TMED1_HUMAN (17-229): 1.71e-60: 191: 57.01
+	Mm
		399003 CFAD_MOUSE (12-256): 1.1e-45: 155: 37.40		TMED5_MOUSE (1-229): 4.29e-81: 243: 89.96
+	Mm
		92694 CFAD_MOUSE (12-256): 1.1e-45: 155: 37.40		D3YZZ5_MOUSE (31-229): 2.57e-68: 211: 31.50
+	Mm
		398554 CFAD_MOUSE (12-256): 1.1e-45: 155: 37.40		TMED3_MOUSE (30-227): 7.25e-65: 202: 30.15
+	Mm
		398423 CFAD_MOUSE (12-256): 1.1e-45: 155: 37.40		TMED1_MOUSE (23-229): 3.19e-62: 195: 56.73
+	Mm
		398766 CFAD_MOUSE (12-256): 1.1e-45: 155: 37.40		TMED4_MOUSE (17-225): 3.02e-62: 195: 20.63
+	Mm
		399202 CFAD_MOUSE (12-256): 1.1e-45: 155: 37.40		TMED2_MOUSE (34-225): 2.54e-62: 194: 24.87
+	Mm
		398904 CFAD_MOUSE (12-256): 1.1e-45: 155: 37.40		TMED9_MOUSE (32-225): 2.2e-61: 193: 21.36
+	Mm
		399042 CFAD_MOUSE (12-256): 1.1e-45: 155: 37.40		TMEDA_MOUSE (26-225): 5.58e-55: 176: 17.96