Protein: TMED1
Transmembrane emp24 domain-containing protein 1 (Interleukin-1 receptor-like 1 ligand) (Putative T1/ST2 receptor-binding protein) (p24 family protein gamma-1) (Tp24) (p24gamma1)

Gene: TMED1
Organism: Homo sapiens
Interactions: 78
UniProt ID: Q13445

Gene Ontology (top 5):
GO:0005102 - signaling receptor binding
GO:0005783 - endoplasmic reticulum
GO:0005789 - endoplasmic reticulum membrane
GO:0005793 - endoplasmic reticulum-Golgi intermediate compartment
GO:0005794 - Golgi apparatus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

888859

TMEDA
Transmembrane emp24 domain-containing protein 10

5

17

High-throughput

0.925

High

1105843

TMED2
Transmembrane emp24 domain-containing protein 2

4

18

High-throughput

0.900

High

1105869

TMED9
Transmembrane emp24 domain-containing protein 9

1

17

High-throughput

0.691

High

1105860

SPP2B
Signal peptide peptidase-like 2B

3

7

High-throughput

0.662

High

1105866

CK5P3
CDK5 regulatory subunit-associated protein 3

3

5

High-throughput

0.662

High

400782

RAF1
RAF proto-oncogene serine/threonine-protein kinase

3

2

High-throughput

0.633

High

546969

FGF3
Fibroblast growth factor 3

2

7

High-throughput

0.628

High

1105867

JPH4
Junctophilin-4

2

2

High-throughput

0.628

High

1105839

TMED1
Transmembrane emp24 domain-containing protein 1

1

18

Small-scale

0.618

High

1105865

DDRGK
DDRGK domain-containing protein 1

2

5

High-throughput

0.611

High

1105845

CD226
CD226 antigen

2

4

High-throughput

0.601

High

1105873

CHST8
Carbohydrate sulfotransferase 8

3

6

High-throughput

0.593

High

711339

SHC1
SHC-transforming protein 1

2

1

High-throughput

0.571

High

186905

GPR37
Prosaposin receptor GPR37

1

1

High-throughput

0.541

High

936042

PAR2
Proteinase-activated receptor 2

1

7

High-throughput

0.541

High

1105878

LT4R2
Leukotriene B4 receptor 2

1

1

High-throughput

0.541

High

125014

KCNK1
Potassium channel subfamily K member 1

1

1

High-throughput

0.536

High

230314

CREB3
Cyclic AMP-responsive element-binding protein 3

1

1

High-throughput

0.536

High

240146

FGF17
Fibroblast growth factor 17

1

7

High-throughput

0.536

High

351894

S1PR4
Sphingosine 1-phosphate receptor 4

1

5

High-throughput

0.536

High

638189

S1PR1
Sphingosine 1-phosphate receptor 1

1

5

High-throughput

0.536

High

719781

V2R
Vasopressin V2 receptor

1

3

High-throughput

0.536

High

878023

AGRE5
Adhesion G protein-coupled receptor E5

1

4

High-throughput

0.536

High

1105861

AT2A3
Sarcoplasmic/endoplasmic reticulum calcium ATPase 3

1

7

High-throughput

0.536

High

1105875

GORS2
Golgi reassembly-stacking protein 2

1

16

High-throughput

0.536

High

1105876

NOD2
Nucleotide-binding oligomerization domain-containing protein 2

1

9

High-throughput

0.536

High

1105880

GPC5B
G-protein coupled receptor family C group 5 member B

1

3

High-throughput

0.536

High

1105882

VAPA
Vesicle-associated membrane protein-associated protein A

1

8

High-throughput

0.536

High

1105885

LIPG
Endothelial lipase

1

5

High-throughput

0.536

High

252596

TSN2
Tetraspanin-2

1

0

High-throughput

0.513

High

252862

EXOC3
Exocyst complex component 3

1

0

High-throughput

0.513

High

253837

TPST2
Protein-tyrosine sulfotransferase 2

1

0

High-throughput

0.513

High

1098891

KLRD1
Natural killer cells antigen CD94

1

0

High-throughput

0.513

High

1105847

DOXA2
Dual oxidase maturation factor 2

1

0

High-throughput

0.513

High

1105877

SAYS1
SAYSvFN domain-containing protein 1

1

0

High-throughput

0.513

High

1105879

EXOC1
Exocyst complex component 1

1

0

High-throughput

0.513

High

1031669

ILRL1
Interleukin-1 receptor-like 1

1

4

Small-scale

0.501

High

429835

JUN
Transcription factor Jun

1

3

High-throughput

0.489

High

1105853

TPGS1
Tubulin polyglutamylase complex subunit 1

1

1

High-throughput

0.489

High

1105855

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

2

High-throughput

0.489

High

1105883

IKBL1
NF-kappa-B inhibitor-like protein 1

1

1

High-throughput

0.489

High

1105884

KLK5
Kallikrein-5

1

4

High-throughput

0.489

High

1014495

SMAD3
Mothers against decapentaplegic homolog 3

1

0

High-throughput

0.486

High

133744

PDE2A
cGMP-dependent 3',5'-cyclic phosphodiesterase

1

1

High-throughput

0.479

High

218151

TGON2
Trans-Golgi network integral membrane protein 2

1

7

High-throughput

0.479

High

939921

TPTE
Putative tyrosine-protein phosphatase TPTE

1

1

High-throughput

0.479

High

1024552

VIGLN
Vigilin

1

2

High-throughput

0.479

High

1105851

TPTE2
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase TPTE2

1

1

High-throughput

0.479

High

1105859

RN149
E3 ubiquitin-protein ligase RNF149

1

7

High-throughput

0.479

High

1105871

RNF26
E3 ubiquitin-protein ligase RNF26

1

1

High-throughput

0.479

High

1105881

BFAR
Bifunctional apoptosis regulator

1

2

High-throughput

0.479

High

1105862

PLD4
5'-3' exonuclease PLD4

1

0

High-throughput

0.458

High

1105868

RNF5
E3 ubiquitin-protein ligase RNF5

1

0

High-throughput

0.458

High

916091

NKX25
Homeobox protein Nkx-2.5

1

5

High-throughput

0.457

High

211130

CTR4
Cationic amino acid transporter 4

1

17

High-throughput

0.445

High

722453

CTR1
High affinity cationic amino acid transporter 1

1

18

High-throughput

0.445

High

877663

SL9A3
Sodium/hydrogen exchanger 3

1

2

High-throughput

0.445

High

1105840

S39AE
Metal cation symporter ZIP14

1

7

High-throughput

0.445

High

1105848

MFSD5
Molybdate-anion transporter

1

7

High-throughput

0.445

High

1105850

S39A4
Zinc transporter ZIP4

1

7

High-throughput

0.445

High

1105854

NIPA1
Magnesium transporter NIPA1

1

8

High-throughput

0.445

High

1105856

ZNT8
Proton-coupled zinc antiporter SLC30A8

1

12

High-throughput

0.445

High

1105857

S39AB
Zinc transporter ZIP11

1

7

High-throughput

0.445

High

1105870

S12A9
Solute carrier family 12 member 9

1

15

High-throughput

0.445

High

1105872

MAGT1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit MAGT1

1

6

High-throughput

0.445

High

543200

UBL4A
Ubiquitin-like protein 4A

1

7

High-throughput

0.437

High

1105842

KIF14
Kinesin-like protein KIF14

1

7

High-throughput

0.437

High

1105852

TRI67
Tripartite motif-containing protein 67

1

7

High-throughput

0.437

High

1105858

FBXL6
F-box/LRR-repeat protein 6

1

2

High-throughput

0.437

High

1105874

EGLN3
Prolyl hydroxylase EGLN3

1

1

High-throughput

0.437

High

722869

SSR2
Somatostatin receptor type 2

1

0

High-throughput

0.426

High

1105844

SC23B
Protein transport protein Sec23B

1

14

Small-scale

0.408

High

1105849

NPAL3
NIPA-like protein 3

1

8

High-throughput

0.407

High

1105863

SAAL1
Protein SAAL1

1

3

High-throughput

0.407

High

1105841

IQCB1
IQ calmodulin-binding motif-containing protein 1

1

0

High-throughput

0.279

Low

1105864

SGF29
SAGA-associated factor 29

1

0

High-throughput

0.279

Low

1105846

E2F4
Transcription factor E2F4

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025