Interactor 1: HP1 (P05205)
Heterochromatin protein 1 (HP1) (Non-histone chromosomal protein C1A9 antigen)
Gene: Su(var)205

Interactor 2: SETB1 (Q32KD2)
Histone-lysine N-methyltransferase eggless (EC 2.1.1.355) (SETDB1 homolog)
Gene: egg

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.56 0.60 0.584

The method score is based on:

Property Details
Experiments 24990964, 30659116
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005700 - polytene chromosome
GO:0010629 - negative regulation of gene expression
GO:0031507 - heterochromatin formation
GO:0090309 - positive regulation of DNA methylation-dependent heterochromatin formation
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 206
Dm

1 1262
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024