HitPredict

Interactor 1: NALP2 (Q9NX02)
NACHT, LRR and PYD domains-containing protein 2 (Nucleotide-binding site protein 1) (PYRIN domain and NACHT domain-containing protein 1) (PYRIN-containing APAF1-like protein 2)
Gene: NLRP2

Interactor 2: SGT1 (Q9Y2Z0)
Protein SGT1 homolog (Protein 40-6-3) (Sgt1) (Suppressor of G2 allele of SKP1 homolog)
Gene: SUGT1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.612

Property	Details
Experiments	17435760, 17420470
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 1062 Hs			1 365
+	Hs
		1399412 NLRP3_HUMAN (790-1054): 1.25e-46: 184: 34.34		SGT1_HUMAN (1-365): 5.11e-88: 271: 100.00
+	Hs
		947382 NAL12_HUMAN (852-1054): 3.87e-32: 137: 36.45		SGT1_HUMAN (1-365): 5.11e-88: 271: 100.00
+	Hs
		1490476 NOD1_HUMAN (786-1054): 3.33e-26: 118: 23.42		SGT1_HUMAN (1-365): 5.11e-88: 271: 100.00
+	Hs
		1438570 NOD2_HUMAN (844-1054): 5.39e-21: 101: 24.65		SGT1_HUMAN (1-365): 5.11e-88: 271: 100.00
+	Hs
		1398261 NALP4_HUMAN (855-1054): 1.43e-20: 100: 24.00		SGT1_HUMAN (1-365): 5.11e-88: 271: 100.00
+	Hs
		1446613 NLRC4_HUMAN (588-959): 4.66e-20: 98.6: 15.12		SGT1_HUMAN (1-365): 5.11e-88: 271: 100.00
+	Hs
		76513 NAL12_HUMAN (852-1054): 3.87e-32: 137: 36.45		B4DYC6_HUMAN (57-365): 6.48e-64: 206: 87.06
+	Hs
		76591 NOD1_HUMAN (786-1054): 3.33e-26: 118: 23.42		B4DYC6_HUMAN (57-365): 6.48e-64: 206: 87.06
+	Hs
		76518 LR74A_HUMAN (691-945): 3.91e-22: 103: 22.48		B4DYC6_HUMAN (57-365): 6.48e-64: 206: 87.06
+	Hs
		947368 NAL12_HUMAN (852-1054): 3.87e-32: 137: 36.45		Q9BPW0_HUMAN (9-249): 2.08e-39: 147: 14.69
+	Hs
		226740 NAL12_HUMAN (852-1054): 3.87e-32: 137: 36.45		SGTA_HUMAN (6-171): 3.2e-40: 146: 20.96
+	Hs
		1409578 NOD1_HUMAN (786-1054): 3.33e-26: 118: 23.42		Q9BPW0_HUMAN (9-249): 2.08e-39: 147: 14.69
+	Hs
		185394 RINI_HUMAN (756-1056): 7.29e-46: 174: 30.57		OGT1_HUMAN (51-342): 8.9e-18: 86.8: 9.12