HitPredict

Interactor 1: TMOD3 (Q9NYL9)
Tropomodulin-3 (Ubiquitous tropomodulin) (U-Tmod)
Gene: TMOD3

Interactor 2: LRRF2 (Q9Y608)
Leucine-rich repeat flightless-interacting protein 2 (LRR FLII-interacting protein 2)
Gene: LRRFIP2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.50	0.574

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 352 Hs			1 721
+	Hs
		702068 TMOD1_HUMAN (3-348): 1.35e-127: 371: 62.14		LRRF2_HUMAN (1-721): 4.32e-103: 333: 100.00
+	Hs
		1453571 TMOD4_HUMAN (4-346): 1.34e-124: 363: 55.10		LRRF2_HUMAN (1-721): 4.32e-103: 333: 100.00
+	Hs
		1181286 TMOD3_HUMAN (1-352): 1.8e-139: 401: 100.00		LRRF1_HUMAN (280-458): 7.46e-52: 195: 56.35
+	Hs
		701992 TMOD1_HUMAN (3-348): 1.35e-127: 371: 62.14		LRRF1_HUMAN (280-458): 7.46e-52: 195: 56.35
+	Hs
		1181287 TMOD4_HUMAN (4-346): 1.34e-124: 363: 55.10		LRRF1_HUMAN (280-458): 7.46e-52: 195: 56.35
+	Dm
		235122 O46231_DROME (5-351): 1.29e-103: 310: 32.10		Q9VXN3_DROME (355-718): 2.46e-61: 212: 33.97
+	Dm
		69112 A8JRH3_DROME (5-350): 8.27e-101: 308: 31.82		Q9VXN3_DROME (355-718): 2.46e-61: 212: 33.97
+	Hs
		702018 TMOD1_HUMAN (3-348): 1.35e-127: 371: 62.14		DLG5_HUMAN (275-721): 9.23e-29: 125: 11.01
+	Hs
		1365603 TMOD3_HUMAN (1-352): 1.8e-139: 401: 100.00		MY18A_HUMAN (332-715): 3.37e-12: 72.4: 11.16
+	Hs
		773050 TMOD3_HUMAN (1-352): 1.8e-139: 401: 100.00		MYH9_HUMAN (417-721): 3.17e-09: 62.9: 13.12
+	Hs
		702024 TMOD1_HUMAN (3-348): 1.35e-127: 371: 62.14		MY18A_HUMAN (332-715): 3.37e-12: 72.4: 11.16
+	Hs
		701951 TMOD1_HUMAN (3-348): 1.35e-127: 371: 62.14		MYH9_HUMAN (417-721): 3.17e-09: 62.9: 13.12
+	Hs
		772849 CARL1_HUMAN (137-350): 4.58e-29: 120: 17.35		MYH9_HUMAN (417-721): 3.17e-09: 62.9: 13.12