HitPredict

Interactor 1: XPO1 (Q9TVM2)
Exportin-1 (Chromosome region maintenance 1 protein) (Protein embargoed)
Gene: emb

Interactor 2: IPO9 (Q9VGP4)
Importin-9 (Ran-binding protein 9)
Gene: IPO9

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	1.00	0.737

Property	Details
Experiments	22036573, 38944040
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	CRM1_C~IBN_N, IBN_N~Xpo1
Common GO terms	GO:0031267 - small GTPase binding
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 1063 Dm			1 1018
+	Hs
		172618 XPO1_HUMAN (1-1062): 0: 948: 70.72		XPO2_HUMAN (8-953): 9.87e-155: 485: 12.35
+	Hs
		173167 XPO1_HUMAN (1-1062): 0: 948: 70.72		TNPO1_HUMAN (3-928): 2.55e-142: 450: 12.95
+	Dm
		1457457 XPO1_DROME (1-1063): 0: 921: 100.00		Q9VSD6_DROME (15-1015): 2.75e-145: 462: 13.26
+	Hs
		172257 XPO1_HUMAN (1-1062): 0: 948: 70.72		XPO1_HUMAN (3-843): 9.14e-109: 365: 8.86
+	Hs
		172822 XPO1_HUMAN (1-1062): 0: 948: 70.72		IMB1_HUMAN (16-795): 2.35e-106: 353: 10.85
+	Sc
		722234 XPO1_YEAST (11-1058): 0: 828: 42.16		SXM1_YEAST (14-873): 3.35e-106: 355: 14.99
+	Dm
		1474996 Q9VSD6_DROME (20-875): 7.69e-94: 324: 10.48		IPO9_DROME (1-1018): 0: 644: 100.00
+	Sc
		722270 XPO1_YEAST (11-1058): 0: 828: 42.16		IMB1_YEAST (19-796): 1.26e-11: 71: 14.62
+	Hs
		164619 TNPO2_HUMAN (33-893): 1.87e-121: 396: 13.96		TNPO1_HUMAN (3-928): 2.55e-142: 450: 12.95
+	Hs
		164576 TNPO2_HUMAN (33-893): 1.87e-121: 396: 13.96		IMB1_HUMAN (16-795): 2.35e-106: 353: 10.85
+	Hs
		1134317 TNPO1_HUMAN (30-893): 1.13e-118: 388: 14.37		IMB1_HUMAN (16-795): 2.35e-106: 353: 10.85
+	Hs
		173614 TNPO3_HUMAN (22-779): 7.8e-110: 365: 13.93		XPO1_HUMAN (3-843): 9.14e-109: 365: 8.86